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The map label for this gene is invG [H]

Identifier: 194736395

GI number: 194736395

Start: 2948793

End: 2950337

Strand: Reverse

Name: invG [H]

Synonym: SeSA_A3051

Alternate gene names: 194736395

Gene position: 2950337-2948793 (Counterclockwise)

Preceding gene: 194737921

Following gene: 194737917

Centisome position: 62.65

GC content: 46.28

Gene sequence:

>1545_bases
ATGGCGCTACAGCTAAAGGAGCCTGTCATTGTTAGCAAAATGGCGGCACGAAAAAAAATTACGGGCAACTTTGAGTTTCA
CGATCCTAACGCATTACTGGAGAAGCTTTCCCTACAACTGGGGCTGATTTGGTATTTCGATGGGCAGGCTATCTATATTT
ATGACGCCAGTGAAATGCGCAATGCCGTGGTTTCTTTACGCAACGTCTCACTCAATGAGTTCAACAATTTTCTAAAACGC
TCAGGTTTATATAACAAAAATTACCCGCTACGTGGCGATAACCGTAAAGGAACATTCTATGTTTCAGGGCCACCCGTCTA
TGTTGATATGGTGGTCAACGCCGCCACCATGATGGACAAGCAAAACGATGGTATTGAGCTGGGACGCCAGAAAATAGGGG
TGATGCGTCTGAACAATACCTTCGTGGGCGATCGTACCTACAATCTGCGCGATCAGAAAATGGTTATCCCCGGTATTGCT
ACGGCGATTGAAAGGTTATTGCAGGGAGAAGAGCAACCCTTAGGTAATATTGTCAGTAGCGAACCTCCGGCGATGCCAGC
GTTTTCAGCGAATGGAGAAAAAGGTAAAGCAGCAAATTATGCCGGTGGCATGAGTCTGCAGGAAGCTTTAAAGCAAAATG
CCGCGGCGGGCAATATTAAAATCGTGGCCTATCCGGATACCAACAGTTTGTTAGTAAAAGGAACGGCTGAGCAGGTGCAT
TTTATCGAAATGCTGGTTAAAGCGCTGGATGTCGCCAAACGTCACGTAGAATTATCCCTGTGGATTGTCGATCTTAATAA
AAGCGATCTGGAGCGTTTGGGCACTTCATGGAGCGGCAGCATTACTATTGGGGACAAACTTGGCGTGTCATTAAACCAGG
CTTCAATAAGTACCCTTGATGGCAGTCGATTCATCGCCGCGGTAAATGCGTTAGAAGAGAAGAAACAGGCGACGGTGGTT
TCGCGCCCGGTATTACTGACTCAGGAAAATGTTCCCGCTATTTTTGATAACAACAGAACGTTTTACACCAAGCTGATTGG
GGAACGTAATGTGGCGCTTGAGCATGTAACATACGGAACAATGATCCGAGTGCTGCCCCGTTTTTCCGCAGATGGTCAGA
TAGAAATGTCGCTGGACATTGAAGATGGCAACGATAAGACGCCGCAATCCGATACTACCACCTCCGTAGATGCGTTACCC
GAAGTCGGGCGAACGTTAATTAGCACTATTGCGAGAGTTCCGCACGGAAAAAGTTTGCTGGTCGGGGGTTATACACGGGA
TGCAAATACCGATACTGTCCAAAGTATTCCGTTTTTAGGCAAATTACCGCTTATTGGTAGCCTGTTCCGTTATTCCAGTA
AGAATAAAAGTAATGTTGTTCGTGTATTCATGATTGAACCAAAAGAAATTGTCGACCCGTTAACGCCGGATGCCAGCGAA
TCGGTAAACAATATTCTGCAACAAAGCGGTGCCTGGAGTGGGGACGATAAGTTACAGAAATGGGTTCGTGTTTATCTGGA
TAGAGGTCAGGAGGCAATTAAATGA

Upstream 100 bases:

>100_bases
GCTTGTTCTGGTTGCACCTGGTTATTCTAGTGAAAAAATACCTGTAACGGGAAGTGGGTTTGTTGCGAAAGACGATAGCC
TGCGGACATTTTTCGATGCC

Downstream 100 bases:

>100_bases
TTCCTGGCTCAACCTCCGGTATTTCATTTTCCAGAATATTATCCCGGCAGACATCTCACCAGGATGCGACCCAGCATACT
GATGCGCAGCAGGCGGAAAT

Product: type III secretion outer membrane pore, YscC/HrcC family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKR
SGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIA
TAIERLLQGEEQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVH
FIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQASISTLDGSRFIAAVNALEEKKQATVV
SRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALP
EVGRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASE
SVNNILQQSGAWSGDDKLQKWVRVYLDRGQEAIK

Sequences:

>Translated_514_residues
MALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKR
SGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIA
TAIERLLQGEEQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVH
FIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQASISTLDGSRFIAAVNALEEKKQATVV
SRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALP
EVGRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASE
SVNNILQQSGAWSGDDKLQKWVRVYLDRGQEAIK
>Mature_513_residues
ALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSLNEFNNFLKRS
GLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIAT
AIERLLQGEEQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVHF
IEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQASISTLDGSRFIAAVNALEEKKQATVVS
RPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPE
VGRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASES
VNNILQQSGAWSGDDKLQKWVRVYLDRGQEAIK

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be necessary for the export of invasion related determinants [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=261, Percent_Identity=26.4367816091954, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 56658; Mature: 56526

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMR
CCCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHEEEEEEEECCEEEEEEEHHHHH
NAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDK
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHCC
QNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSS
CCCCHHHHHHHEEEEEECCEEECCEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCHHCC
EPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVH
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEECCHHHHH
FIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQASISTLD
HHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHCCCCCCCCEEECCCCCCEECCCEEEECC
GSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGT
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCCCEEEHHHHHH
MIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLL
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
VGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASE
EECEECCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCCHHH
SVNNILQQSGAWSGDDKLQKWVRVYLDRGQEAIK
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure 
ALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMR
CCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHEEEEEEEECCEEEEEEEHHHHH
NAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDK
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHCC
QNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSS
CCCCHHHHHHHEEEEEECCEEECCEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCHHCC
EPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVH
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEECCHHHHH
FIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDKLGVSLNQASISTLD
HHHHHHHHHHHHHHEEEEEEEEEECCHHHHHHCCCCCCCCEEECCCCCCEECCCEEEECC
GSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEHVTYGT
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEECCCCCCEEEHHHHHH
MIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIARVPHGKSLL
HHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEE
VGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVDPLTPDASE
EECEECCCCCCHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCCHHH
SVNNILQQSGAWSGDDKLQKWVRVYLDRGQEAIK
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7868245; 7997169; 11677609 [H]