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The map label for this gene is recG [H]

Identifier: 194735749

GI number: 194735749

Start: 3822043

End: 3824124

Strand: Direct

Name: recG [H]

Synonym: SeSA_A3952

Alternate gene names: 194735749

Gene position: 3822043-3824124 (Clockwise)

Preceding gene: 194735347

Following gene: 194734456

Centisome position: 81.16

GC content: 58.74

Gene sequence:

>2082_bases
ATGTCAGGCCGCTTGTTAGACGCTGTTCCGCTCAATTCCCTGACAGGCGTCGGCGCAGCGCAAAGCAGTAAACTGGCGAA
AATTGGCCTGCACACCGTGCAGGACCTCCTGCTCCACCTCCCTCTGCGTTACGAAGACCGCACCCATCTCTACCCCATTG
GCGAACTGCTGCCTGGCATCTACGCCACCGTTGAAGGTGAAGTGCTGAACTGCAATATCACTTTCGGCGGTCGTCGGATG
ATGACCTGCCAGATTAGCGACGGTTCCGGCATTCTTACCATGCGCTTTTTCAATTTTAACGCGGCGATGAAAAACAGCCT
GGCGACGGGACGGCGTGTGCTGGCCTACGGGGAAGCGAAGCGCGGCAAGTATGGCGCAGAGATGATCCATCCGGAATATC
GCCTGCAGGGCGATCTCAGCACGCCGGAACTTCAGGAAACGCTCACCCCCGTCTATCCGACCACCGAGGGCGTGAAGCAA
GCGACACTGCGCAAGCTTACCGATCAGGCGCTGGAGCTGCTCGACACCTGCGCCATTGCCGAACTACTGCCGCCGGAACT
GGCGCAGGGTATGATGAGCCTGCCGGAGGCGCTACGTACCTTGCATCGCCCGCCGCCGACACTCCAGCTCGCCGATTTAG
AAACCGGTAAACACCCGGCGCAGCGGCGGCTTATTCTTGAAGAGCTACTGGCGCATAACCTCAGTATGCTGGCACTTCGC
GCAGGCGCGCAGCGCTACCACGCTCAGCCGCTAAGTACCAACAACATATTGAAAGACAATCTGCTGGCGTCGTTGCCGTT
TAAACCCACCAGCGCGCAGGCGCGGGTGGTAGCAGAGATCGAACGTGATATGGCTCTGGATGTGCCGATGATGCGTCTGG
TTCAGGGCGACGTCGGCTCAGGGAAAACGCTGGTTGCGGCGCTTGCCGCCTTGCGCGCTATTGCCCACGGTAAGCAGGTG
GCGCTGATGGCGCCGACCGAATTGCTGGCTGAACAGCACGCAAATAATTTCCGCAACTGGTTCGAACCGTTGGGCGTTGA
AGTGGGTTGGCTGGCAGGTAAGCAAAAAGGTAAAGCGCGTCAGGCGCAGCAAGAGGCTATTGCCAGCGGTCAGGTGCAGA
TGATTGTCGGCACCCACGCTATCTTTCAGGAACAGGTGCAGTTTAACGGGCTGGCGCTGGTGATCATCGACGAACAGCAC
CGCTTTGGCGTCCACCAGCGTCTGGCGCTGTGGGAAAAAGGCCAGCAGCAGGGCTTTCACCCACATCAGTTGATTATGAC
CGCAACGCCCATTCCGCGCACCCTGGCGATGACTGCCTACGCCGATCTCGATACCTCGGTGATTGACGAGCTACCGCCGG
GCCGTACCCCTGTCACTACCGTTGCGATTCCGGATACCCGTCGCCATGAAATCATTGATCGTGTGCGCAACGCCTGCACA
ACCGAAGGCCGTCAGGCCTACTGGGTCTGTACGCTGATTGAAGAGTCCGACCTGCTGGAAGCGCAGGCGGCGGAAGCCAC
CTGGGAGGAGCTCAAGCTGGCGCTGCCGGAGTTGAATATTGGCCTGGTACACGGCCGCATGAAGCCCGCCGAAAAACAGG
CGGTGATGCAGGCCTTTAAGCAGGGTGAACTGCATCTGCTGGTCGCCACTACGGTGATTGAGGTGGGGGTCGATGTTCCT
AACGCCAGCCTGATGATTATTGAAAACCCGGAGCGGCTGGGCCTGGCGCAGTTACACCAGCTCAGAGGGCGCGTTGGCCG
TGGCGCGGTCGCATCGCACTGCGTGCTGCTCTATAAATCGCCGCTGTCGAAAACGGCGCAGAAGCGTTTACAGGTATTGC
GCGACAGCAACGACGGCTTTGTGATTGCACAAAAAGATTTAGAGATTCGCGGCCCGGGGGAATTACTGGGCACGCGCCAG
ACGGGTAACGCCGAATTTAAAGTAGCTGATTTGCTGCGCGATCAAGCCATGATCCCCGAAGTTCAGCGTATTGCCCGTCA
TATTCACGAACGTTATCCGCAGCAGGCACAAGCGCTGATTGAGCGCTGGATGCCGGAAACCGAACGTTATTCCAACGCCT
AA

Upstream 100 bases:

>100_bases
CTAAACGTAAAGGTCTGCCTTATCCTCGCGTCAATCAGCAGGGCGAAATCGACGCCGATGCTGACTGGTGGGCGACGATG
CAGGCGGCAGGGTAATCACC

Downstream 100 bases:

>100_bases
TGAGCACGGCGGCTTTAATGCCGCCGTACAAACTATTATTGCGCGAAAATCGGTAACAGCAGGTACAGCTTGATTACCAA
CGCATTAACGATATCGATAA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MSGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIGELLPGIYATVEGEVLNCNITFGGRRM
MTCQISDGSGILTMRFFNFNAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQ
ATLRKLTDQALELLDTCAIAELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKHPAQRRLILEELLAHNLSMLALR
AGAQRYHAQPLSTNNILKDNLLASLPFKPTSAQARVVAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHANNFRNWFEPLGVEVGWLAGKQKGKARQAQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQH
RFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRHEIIDRVRNACT
TEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGELHLLVATTVIEVGVDVP
NASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQ
TGNAEFKVADLLRDQAMIPEVQRIARHIHERYPQQAQALIERWMPETERYSNA

Sequences:

>Translated_693_residues
MSGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIGELLPGIYATVEGEVLNCNITFGGRRM
MTCQISDGSGILTMRFFNFNAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQ
ATLRKLTDQALELLDTCAIAELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKHPAQRRLILEELLAHNLSMLALR
AGAQRYHAQPLSTNNILKDNLLASLPFKPTSAQARVVAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHANNFRNWFEPLGVEVGWLAGKQKGKARQAQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQH
RFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRHEIIDRVRNACT
TEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGELHLLVATTVIEVGVDVP
NASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQ
TGNAEFKVADLLRDQAMIPEVQRIARHIHERYPQQAQALIERWMPETERYSNA
>Mature_692_residues
SGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIGELLPGIYATVEGEVLNCNITFGGRRMM
TCQISDGSGILTMRFFNFNAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQA
TLRKLTDQALELLDTCAIAELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKHPAQRRLILEELLAHNLSMLALRA
GAQRYHAQPLSTNNILKDNLLASLPFKPTSAQARVVAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVA
LMAPTELLAEQHANNFRNWFEPLGVEVGWLAGKQKGKARQAQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQHR
FGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRHEIIDRVRNACTT
EGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGELHLLVATTVIEVGVDVPN
ASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQT
GNAEFKVADLLRDQAMIPEVQRIARHIHERYPQQAQALIERWMPETERYSNA

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=94.2279942279942, Blast_Score=1322, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=390, Percent_Identity=39.2307692307692, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76583; Mature: 76451

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIGELLPGI
CCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHCCCC
YATVEGEVLNCNITFGGRRMMTCQISDGSGILTMRFFNFNAAMKNSLATGRRVLAYGEAK
EEEECCEEEEEEEEECCCEEEEEEECCCCCEEEEEEEECCHHHHHHHHCCCEEEEECCCC
RGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQATLRKLTDQALELLDTCAIA
CCCCCHHHCCCCCEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKHPAQRRLILEELLAHNLSMLALR
HHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHH
AGAQRYHAQPLSTNNILKDNLLASLPFKPTSAQARVVAEIERDMALDVPMMRLVQGDVGS
HHHHHHCCCCCCCCCCHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCC
GKTLVAALAALRAIAHGKQVALMAPTELLAEQHANNFRNWFEPLGVEVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
QAQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQHRFGVHQRLALWEKGQQQGFH
HHHHHHHHCCCEEEEECHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHCCCC
PHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRHEIIDRVRNACT
CCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHC
TEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFK
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
QGELHLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKS
CCCEEEEEEHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCHHHHHHHHEECC
PLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPE
HHHHHHHHHHHHHHCCCCCEEEEECCCEECCCHHHCCCCCCCCCCCHHHHHHHHHHCCHH
VQRIARHIHERYPQQAQALIERWMPETERYSNA
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHCCCC
>Mature Secondary Structure 
SGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRYEDRTHLYPIGELLPGI
CCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHCCCC
YATVEGEVLNCNITFGGRRMMTCQISDGSGILTMRFFNFNAAMKNSLATGRRVLAYGEAK
EEEECCEEEEEEEEECCCEEEEEEECCCCCEEEEEEEECCHHHHHHHHCCCEEEEECCCC
RGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQATLRKLTDQALELLDTCAIA
CCCCCHHHCCCCCEECCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKHPAQRRLILEELLAHNLSMLALR
HHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHH
AGAQRYHAQPLSTNNILKDNLLASLPFKPTSAQARVVAEIERDMALDVPMMRLVQGDVGS
HHHHHHCCCCCCCCCCHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCC
GKTLVAALAALRAIAHGKQVALMAPTELLAEQHANNFRNWFEPLGVEVGWLAGKQKGKAR
CHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHH
QAQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQHRFGVHQRLALWEKGQQQGFH
HHHHHHHHCCCEEEEECHHHHHHHHHHHCCEEEEEECCCHHCCHHHHHHHHHHHHHCCCC
PHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRHEIIDRVRNACT
CCEEEEECCCCCHHHHHHHHHCCCHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHC
TEGRQAYWVCTLIEESDLLEAQAAEATWEELKLALPELNIGLVHGRMKPAEKQAVMQAFK
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
QGELHLLVATTVIEVGVDVPNASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKS
CCCEEEEEEHHHHHHCCCCCCCEEEEEECCHHCCHHHHHHHHHCCCCCHHHHHHHHEECC
PLSKTAQKRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPE
HHHHHHHHHHHHHHCCCCCEEEEECCCEECCCHHHCCCCCCCCCCCHHHHHHHHHHCCHH
VQRIARHIHERYPQQAQALIERWMPETERYSNA
HHHHHHHHHHHCCHHHHHHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]