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The map label for this gene is spaK

Identifier: 194735438

GI number: 194735438

Start: 2945165

End: 2945572

Strand: Reverse

Name: spaK

Synonym: SeSA_A3048

Alternate gene names: 194735438

Gene position: 2945572-2945165 (Counterclockwise)

Preceding gene: 194736186

Following gene: 194735197

Centisome position: 62.55

GC content: 44.61

Gene sequence:

>408_bases
ATGCAACATTTGGATATCGCTGAATTAGTTCGTTCCGCACTGGAAGTAAGTGGTTGCGATCCTTCACTCATCGGAGGAAT
AGATAGCCATTCAACAATTGTTCTGGATTTATTTGCATTGCCAAGTATCTGTATCAGCGTCAAGGACGATGATGTATGGA
TCTGGGCGCAATTGGGTGCTGACAGCATGGTGGTATTACAACAGCGGGCTTATGAAATCTTAATGACCATAATGGAAGGA
TGCCATTTTGCCCGCGGCGGGCAATTACTACTGGGGGAGCAGAATGGGGAGCTAACGCTTAAAGCCTTAGTGCATCCGGA
TTTTTTATCTGACGGTGAAAAGTTCTCTACTGCCTTGAATGGGTTTTACAACTATCTGGAAGTTTTTAGTCGGTCGCTAA
TGAGATGA

Upstream 100 bases:

>100_bases
GTTTTCCGGATCTGGAGGTTTTATCTTTCGGTGAGATAGCAGATAGCAAGTCAGTGAATGTTATAAAAACAATATAAGGG
CTTAATTAAGGAAAAGATCT

Downstream 100 bases:

>100_bases
AAACACCTCGTTTACTGCAATATCTGGCCTACCCACAAAAAATAACCGGCCCAATTATTGAGGCGGAATTGCGCGATGTA
GCCATTGGCGAACTGTGTGA

Product: surface presentation of antigens protein SpaK

Products: NA

Alternate protein names: Invasion protein invB

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSICISVKDDDVWIWAQLGADSMVVLQQRAYEILMTIMEG
CHFARGGQLLLGEQNGELTLKALVHPDFLSDGEKFSTALNGFYNYLEVFSRSLMR

Sequences:

>Translated_135_residues
MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSICISVKDDDVWIWAQLGADSMVVLQQRAYEILMTIMEG
CHFARGGQLLLGEQNGELTLKALVHPDFLSDGEKFSTALNGFYNYLEVFSRSLMR
>Mature_135_residues
MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSICISVKDDDVWIWAQLGADSMVVLQQRAYEILMTIMEG
CHFARGGQLLLGEQNGELTLKALVHPDFLSDGEKFSTALNGFYNYLEVFSRSLMR

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spaK family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPAK_SALTI (P0A1N1)

Other databases:

- EMBL:   AL627276
- EMBL:   AE014613
- RefSeq:   NP_457289.1
- RefSeq:   NP_806498.1
- ProteinModelPortal:   P0A1N1
- SMR:   P0A1N1
- PRIDE:   P0A1N1
- GeneID:   1068860
- GeneID:   1249324
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2797
- KEGG:   sty:STY3018
- HOGENOM:   HBG391032
- OMA:   HSTIALD
- ProtClustDB:   PRK15336
- BioCyc:   SENT209261:T2797-MONOMER
- BioCyc:   SENT220341:STY3018-MONOMER
- GO:   GO:0009405
- InterPro:   IPR003065
- PRINTS:   PR01305

Pfam domain/function: PF03519 Invas_SpaK

EC number: NA

Molecular weight: Translated: 14919; Mature: 14919

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSICISVKDDDVWIWAQLGA
CCCCCHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCC
DSMVVLQQRAYEILMTIMEGCHFARGGQLLLGEQNGELTLKALVHPDFLSDGEKFSTALN
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCHHCCCHHHHHHHH
GFYNYLEVFSRSLMR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSICISVKDDDVWIWAQLGA
CCCCCHHHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEECCC
DSMVVLQQRAYEILMTIMEGCHFARGGQLLLGEQNGELTLKALVHPDFLSDGEKFSTALN
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCHHCCCHHHHHHHH
GFYNYLEVFSRSLMR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504