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The map label for this gene is ptrB [H]

Identifier: 194735292

GI number: 194735292

Start: 1950368

End: 1952419

Strand: Reverse

Name: ptrB [H]

Synonym: SeSA_A2033

Alternate gene names: 194735292

Gene position: 1952419-1950368 (Counterclockwise)

Preceding gene: 194737643

Following gene: 194737914

Centisome position: 41.46

GC content: 51.17

Gene sequence:

>2052_bases
ATGTTGCCAAAAGCCAATCGAATTCCCTATGCCATGACCGTACATGGCGATACGCGCATTGATAATTATTACTGGCTGCG
AGATGACACTCGCTCGCAGCCGGAAGTCCTTGATTACCTGCATCAGGAAAATGAGTATGGCCGGAAGGTCATGTCCTCTC
AGCAGGCGTTACAGGACCGCATTCTAAAAGAAATTATCGATCGTATCCCGCCCAGAGAAGTTTCCGCTCCGTATGTGAAA
AACGGCTATCGCTACCGTTATATCTATGAACCCGGCTGCGAATATGCCATCTATCAACGACAATCGGCGTTAAGCGAAGA
GTGGGATGTGTGGGAAACCTTGCTCGATGCGAACCAGCGGGCCGCGCACAGCGAATTTTATACGCTCGGTGGACTTGCCA
TTACGCCGGATAATACCATTATGGCGCTGGCAGAAGATTATTTATCCCGTCGTCAGTATGGGTTGCGTTTTCGTAACCTC
GAAAGCGGTAACTGGTATCCGGAACTGCTGGATAACGTTGCGCCTGAATTTGTCTGGGCCAATGATTCCCTGACCCTTTA
CTATGTGCGTAAGCATAAGAAGACGCTGCTGCCCTATCAGGTTTGGCGGCACACGATTGGCACTCCGTCATCGCAAGATG
AACTGGTATATGAAGAGAAAGACGATACCTTTTATGTCAGCCTGCATAAAACCACTTCGCAGCATTATGTGGTGATTCAT
CTTGCCAGCGCCACCACTAGCGAAGTGCTGTTACTTGACGCGGAACTGGCCGATGCCGAGCCGTTTTCATTCTTACCGCG
CCGCAAAGACCACGAATATAGTCTCGATCACTATCAACATAAGTTTTACCTGCGTTCTAACCGGAACGGTAAAAACTTTG
GGTTGTACCGTACCCGCGTGCGCAATGAAAACGCCTGGGAAGAGCTGATCCCTCCGCGCGAGCATATTATGCTGGAAGGG
TTTACCCTGTTTACCGACTGGTTAGTGGTCGAAGAGCGTCAACGGGGGCTTACCAGCCTGCGGCAAATTAACCGTAAAAC
CCGTGAAGTGATAGGCATTGCCTTTGACGATCCGGCTTACGTGACGTGGCTTGCCTATAATCCCGAACCTGAGACCTCCC
GGCTGCGTTACGGCTATTCTTCAATGACGACGCCAGATACCTTGTTTGAACTGGATATGGATACCGGAGAACGACGGGTA
CTTAAACAGACGGAAGTGCCTGGGTTTGATTCTGGCTGTTATCAGAGCGAACACCTGTGGATCACCGCGCGCGACGGCGT
CGAAGTGCCGGTATCGCTGGTTTATCATCAGAAGTATTTTCGTAAAGGGCAAAATCCGCTTCTGGTTTACGGCTACGGAT
CTTACGGTTCCAGTATTGACGCCGACTTCAGCAGCAGCCGACTGAGCTTGCTGGATCGTGGCTTTGTTTACGCAATCGTA
CACGTTCGCGGCGGCGGTGAGCTGGGGCAGCAGTGGTATGAAGATGGCAAGTTCCTCAAAAAGCGGAATACTTTTAATGA
TTATCTTGATGCCTGCGATGCCTTATTAAAACTGGGTTACGGTTCGCCGTCGCTGTGTTACGGGATGGGCGGGAGCGCGG
GCGGAATGTTAATGGGCGTCGCTATCAACGAACGCCCCGAGCTTTTCCACGGCGTTATTGCCCAGGTACCCTTTGTTGAT
GTATTAACCACGATGCTGGATGAGTCGATCCCACTAACGACAGGAGAGTTTGAAGAGTGGGGGAACCCGCAGGATATTGA
GTATTATGACTATATGAAAAGCTATAGTCCTTATGACAATGTCAAAGCGCAGGACTATCCGCACCTGCTGGTGACGACAG
GATTGCACGATTCCCAGGTGCAATACTGGGAACCGGCGAAGTGGGTGGCAAAATTACGCGAGCTAAAAACGGACCAACGT
CTGCTGCTGTTATGTACGGATATGGACTCCGGGCACGGTGGTAAGTCGGGGCGGTTTAAATCCTACGAAGGCGTCGCGCT
GGAGTTCGCCTTTTTAATCGGCCTGGCGCAGGGAACCTTACATAGCGCATAG

Upstream 100 bases:

>100_bases
TCTCAGGCGCTTACCGAGGTGAGCGACCGGGACTACCATGCTACGCCGCTGTGTTTGCCGCGTGATATATAACAAATATT
AACGCAAAAGAAAAAACGAC

Downstream 100 bases:

>100_bases
ACGCGCGCGCCCGCAACGGCTTGTGAGCGTCTCGGGTTATTGTGGTGTTCCATTGCTGCGTTGCTCGTCAGCCTGAACAT
CTTCCAGGTAGTGTTTAAGC

Product: protease 2

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MLPKANRIPYAMTVHGDTRIDNYYWLRDDTRSQPEVLDYLHQENEYGRKVMSSQQALQDRILKEIIDRIPPREVSAPYVK
NGYRYRYIYEPGCEYAIYQRQSALSEEWDVWETLLDANQRAAHSEFYTLGGLAITPDNTIMALAEDYLSRRQYGLRFRNL
ESGNWYPELLDNVAPEFVWANDSLTLYYVRKHKKTLLPYQVWRHTIGTPSSQDELVYEEKDDTFYVSLHKTTSQHYVVIH
LASATTSEVLLLDAELADAEPFSFLPRRKDHEYSLDHYQHKFYLRSNRNGKNFGLYRTRVRNENAWEELIPPREHIMLEG
FTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYVTWLAYNPEPETSRLRYGYSSMTTPDTLFELDMDTGERRV
LKQTEVPGFDSGCYQSEHLWITARDGVEVPVSLVYHQKYFRKGQNPLLVYGYGSYGSSIDADFSSSRLSLLDRGFVYAIV
HVRGGGELGQQWYEDGKFLKKRNTFNDYLDACDALLKLGYGSPSLCYGMGGSAGGMLMGVAINERPELFHGVIAQVPFVD
VLTTMLDESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDNVKAQDYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDQR
LLLLCTDMDSGHGGKSGRFKSYEGVALEFAFLIGLAQGTLHSA

Sequences:

>Translated_683_residues
MLPKANRIPYAMTVHGDTRIDNYYWLRDDTRSQPEVLDYLHQENEYGRKVMSSQQALQDRILKEIIDRIPPREVSAPYVK
NGYRYRYIYEPGCEYAIYQRQSALSEEWDVWETLLDANQRAAHSEFYTLGGLAITPDNTIMALAEDYLSRRQYGLRFRNL
ESGNWYPELLDNVAPEFVWANDSLTLYYVRKHKKTLLPYQVWRHTIGTPSSQDELVYEEKDDTFYVSLHKTTSQHYVVIH
LASATTSEVLLLDAELADAEPFSFLPRRKDHEYSLDHYQHKFYLRSNRNGKNFGLYRTRVRNENAWEELIPPREHIMLEG
FTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYVTWLAYNPEPETSRLRYGYSSMTTPDTLFELDMDTGERRV
LKQTEVPGFDSGCYQSEHLWITARDGVEVPVSLVYHQKYFRKGQNPLLVYGYGSYGSSIDADFSSSRLSLLDRGFVYAIV
HVRGGGELGQQWYEDGKFLKKRNTFNDYLDACDALLKLGYGSPSLCYGMGGSAGGMLMGVAINERPELFHGVIAQVPFVD
VLTTMLDESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDNVKAQDYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDQR
LLLLCTDMDSGHGGKSGRFKSYEGVALEFAFLIGLAQGTLHSA
>Mature_683_residues
MLPKANRIPYAMTVHGDTRIDNYYWLRDDTRSQPEVLDYLHQENEYGRKVMSSQQALQDRILKEIIDRIPPREVSAPYVK
NGYRYRYIYEPGCEYAIYQRQSALSEEWDVWETLLDANQRAAHSEFYTLGGLAITPDNTIMALAEDYLSRRQYGLRFRNL
ESGNWYPELLDNVAPEFVWANDSLTLYYVRKHKKTLLPYQVWRHTIGTPSSQDELVYEEKDDTFYVSLHKTTSQHYVVIH
LASATTSEVLLLDAELADAEPFSFLPRRKDHEYSLDHYQHKFYLRSNRNGKNFGLYRTRVRNENAWEELIPPREHIMLEG
FTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYVTWLAYNPEPETSRLRYGYSSMTTPDTLFELDMDTGERRV
LKQTEVPGFDSGCYQSEHLWITARDGVEVPVSLVYHQKYFRKGQNPLLVYGYGSYGSSIDADFSSSRLSLLDRGFVYAIV
HVRGGGELGQQWYEDGKFLKKRNTFNDYLDACDALLKLGYGSPSLCYGMGGSAGGMLMGVAINERPELFHGVIAQVPFVD
VLTTMLDESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDNVKAQDYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDQR
LLLLCTDMDSGHGGKSGRFKSYEGVALEFAFLIGLAQGTLHSA

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=694, Percent_Identity=24.9279538904899, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI284172420, Length=472, Percent_Identity=30.0847457627119, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI284172413, Length=472, Percent_Identity=30.0847457627119, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI70778815, Length=472, Percent_Identity=30.0847457627119, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI284172438, Length=472, Percent_Identity=30.0847457627119, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI284172431, Length=472, Percent_Identity=30.0847457627119, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI108860686, Length=218, Percent_Identity=41.2844036697248, Blast_Score=153, Evalue=7e-37,
Organism=Homo sapiens, GI108860692, Length=215, Percent_Identity=41.3953488372093, Blast_Score=152, Evalue=9e-37,
Organism=Escherichia coli, GI1788150, Length=680, Percent_Identity=89.5588235294118, Blast_Score=1288, Evalue=0.0,
Organism=Drosophila melanogaster, GI24583414, Length=697, Percent_Identity=23.6728837876614, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI221510989, Length=697, Percent_Identity=23.9598278335725, Blast_Score=152, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 78960; Mature: 78960

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPKANRIPYAMTVHGDTRIDNYYWLRDDTRSQPEVLDYLHQENEYGRKVMSSQQALQDR
CCCCCCCCCEEEEECCCCEECCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILKEIIDRIPPREVSAPYVKNGYRYRYIYEPGCEYAIYQRQSALSEEWDVWETLLDANQR
HHHHHHHHCCCCCCCCCHHHCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCH
AAHSEFYTLGGLAITPDNTIMALAEDYLSRRQYGLRFRNLESGNWYPELLDNVAPEFVWA
HHHCCEEEECCEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCEEEE
NDSLTLYYVRKHKKTLLPYQVWRHTIGTPSSQDELVYEEKDDTFYVSLHKTTSQHYVVIH
CCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEE
LASATTSEVLLLDAELADAEPFSFLPRRKDHEYSLDHYQHKFYLRSNRNGKNFGLYRTRV
EECCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCHHEEEEEEEECCCCCCCCEEEEEE
RNENAWEELIPPREHIMLEGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAY
CCCCCHHHHCCCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCE
VTWLAYNPEPETSRLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFDSGCYQSEHLW
EEEEEECCCCCCHHEEECCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCEEE
ITARDGVEVPVSLVYHQKYFRKGQNPLLVYGYGSYGSSIDADFSSSRLSLLDRGFVYAIV
EEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEE
HVRGGGELGQQWYEDGKFLKKRNTFNDYLDACDALLKLGYGSPSLCYGMGGSAGGMLMGV
EEECCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEE
AINERPELFHGVIAQVPFVDVLTTMLDESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDN
EECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHCCCCCCC
VKAQDYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDQRLLLLCTDMDSGHGGKSGRFK
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCC
SYEGVALEFAFLIGLAQGTLHSA
CCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLPKANRIPYAMTVHGDTRIDNYYWLRDDTRSQPEVLDYLHQENEYGRKVMSSQQALQDR
CCCCCCCCCEEEEECCCCEECCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
ILKEIIDRIPPREVSAPYVKNGYRYRYIYEPGCEYAIYQRQSALSEEWDVWETLLDANQR
HHHHHHHHCCCCCCCCCHHHCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCH
AAHSEFYTLGGLAITPDNTIMALAEDYLSRRQYGLRFRNLESGNWYPELLDNVAPEFVWA
HHHCCEEEECCEEECCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHCCCCCEEEE
NDSLTLYYVRKHKKTLLPYQVWRHTIGTPSSQDELVYEEKDDTFYVSLHKTTSQHYVVIH
CCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEE
LASATTSEVLLLDAELADAEPFSFLPRRKDHEYSLDHYQHKFYLRSNRNGKNFGLYRTRV
EECCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCHHEEEEEEEECCCCCCCCEEEEEE
RNENAWEELIPPREHIMLEGFTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAY
CCCCCHHHHCCCHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCE
VTWLAYNPEPETSRLRYGYSSMTTPDTLFELDMDTGERRVLKQTEVPGFDSGCYQSEHLW
EEEEEECCCCCCHHEEECCCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCEEE
ITARDGVEVPVSLVYHQKYFRKGQNPLLVYGYGSYGSSIDADFSSSRLSLLDRGFVYAIV
EEECCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEE
HVRGGGELGQQWYEDGKFLKKRNTFNDYLDACDALLKLGYGSPSLCYGMGGSAGGMLMGV
EEECCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEE
AINERPELFHGVIAQVPFVDVLTTMLDESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDN
EECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHCCCCCCC
VKAQDYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDQRLLLLCTDMDSGHGGKSGRFK
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCC
SYEGVALEFAFLIGLAQGTLHSA
CCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]