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The map label for this gene is aadA [H]

Identifier: 194734256

GI number: 194734256

Start: 1313180

End: 1314049

Strand: Direct

Name: aadA [H]

Synonym: SeSA_A1354

Alternate gene names: 194734256

Gene position: 1313180-1314049 (Clockwise)

Preceding gene: 194734627

Following gene: 194737756

Centisome position: 27.89

GC content: 53.56

Gene sequence:

>870_bases
ATGAATAGCGAGCTTTTTTTCTGCCGTTATGCCATATTTCTGGCAATCAATATAAAAAATACCTGCGCCCCCGGAGCGAT
GATGACGCTGTCCATACCGCCCTCGATTCAATGCCAAACGGAAGCGGCATGTCGCCTGATTACTCGTGTCACAGGCGATA
CGTTGCGTGCTATTCATTTATATGGTTCCGCTGTCGCGGGCGGTCTGAAGCCAAACAGCGACATTGATCTGCTGGTGACA
ATATGCCAGCCGCTGACGGAGACCCAACGCGCAACGCTGATGCAGGAATTGCTGGCGCTTTCATCGCCGCCGGGGGCGTC
GGCAGAAAAACGCGCTCTGGAGGTCACTGTCGTGCTTTATTCGCAGCTGGTTCCCTGGTGTTTTCCACCTTCCAGGGAAA
TGCAATTTGGCGAGTGGCTAAGAGAGGACATTTGTCAGGGGATTTATGAACCAGCGCAGCAGGACTGGGACATTGTGTTA
CTGATAACCCAAATTCTGGAAACCAGTATACCGCTAAAGGGCGAACGCGCGGAACGGCTGTTCACGCCAGCCCCTGCGGC
GCAGTTGCTGAAGGCCTTGCGTTATCCCCTCGACCTTTGGCAATCCACGGCAGATGTGCAGGGAGATGAGTATCATATCG
TTTTAACCCTGGCGCGTATCTGGTACACCCTTTCTACCGGGAGATTTACCTCTAAGGATGCGGCGGCTGACTGGCTGTTA
CCTCAGTTGCCGGAAGATTATGCTGCCACGTTGCGTGCGGCGCAGCGTGAATATTTAGGTCTGGAGCAGCAGGACTGGCA
TATTTTGCTGCCTGCGGTCGTACGCTTTGTGGATTTTGCGAAAACGCACATCCCCACGCAGTTCACATAA

Upstream 100 bases:

>100_bases
GGAAAACTGGCCTACCTATTATCCTTATCAGTTAAAGGCGAATGAGGTCGTTGACGAAATGCTACATCATTAAGTCTGAT
TGCAATGTTAAAAGCTCGCT

Downstream 100 bases:

>100_bases
GATGCCCCAGGACGTCTGTCAGGTTGCGCAAACGGCGTTCCTCAACTACTACTTAATAGGTTCTCATCGCTGAAGTAAGC
AGATGATCTTATGCGGGCCA

Product: aminoglycoside resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNSELFFCRYAIFLAINIKNTCAPGAMMTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVT
ICQPLTETQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDIVL
LITQILETSIPLKGERAERLFTPAPAAQLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLL
PQLPEDYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKTHIPTQFT

Sequences:

>Translated_289_residues
MNSELFFCRYAIFLAINIKNTCAPGAMMTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVT
ICQPLTETQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDIVL
LITQILETSIPLKGERAERLFTPAPAAQLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLL
PQLPEDYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKTHIPTQFT
>Mature_289_residues
MNSELFFCRYAIFLAINIKNTCAPGAMMTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGGLKPNSDIDLLVT
ICQPLTETQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDIVL
LITQILETSIPLKGERAERLFTPAPAAQLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLL
PQLPEDYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKTHIPTQFT

Specific function: Mediates bacterial resistance to the antibiotics streptomycin and spectomycin [H]

COG id: COG1708

COG function: function code R; Predicted nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002934 [H]

Pfam domain/function: PF01909 NTP_transf_2 [H]

EC number: =2.7.7.47 [H]

Molecular weight: Translated: 32412; Mature: 32412

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSELFFCRYAIFLAINIKNTCAPGAMMTLSIPPSIQCQTEAACRLITRVTGDTLRAIHL
CCCCHHHHEEEEEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHH
YGSAVAGGLKPNSDIDLLVTICQPLTETQRATLMQELLALSSPPGASAEKRALEVTVVLY
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDIVLLITQILETSIPLKGERAERL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHH
FTPAPAAQLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLL
CCCCCHHHHHHHHHCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHC
PQLPEDYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKTHIPTQFT
CCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNSELFFCRYAIFLAINIKNTCAPGAMMTLSIPPSIQCQTEAACRLITRVTGDTLRAIHL
CCCCHHHHEEEEEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHH
YGSAVAGGLKPNSDIDLLVTICQPLTETQRATLMQELLALSSPPGASAEKRALEVTVVLY
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SQLVPWCFPPSREMQFGEWLREDICQGIYEPAQQDWDIVLLITQILETSIPLKGERAERL
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHH
FTPAPAAQLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLL
CCCCCHHHHHHHHHCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHHHHC
PQLPEDYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKTHIPTQFT
CCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3054482; 2997737; 2986186; 3037494; 2821509; 2823258; 2188588 [H]