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The map label for this gene is znuA [H]

Identifier: 194734060

GI number: 194734060

Start: 1964978

End: 1965922

Strand: Reverse

Name: znuA [H]

Synonym: SeSA_A2045

Alternate gene names: 194734060

Gene position: 1965922-1964978 (Counterclockwise)

Preceding gene: 194735485

Following gene: 194734531

Centisome position: 41.75

GC content: 50.58

Gene sequence:

>945_bases
ATGTTACAGAAAAATACGCTTCTTTTCGCAGCATTATCCGCCGCGCTTTGGGGGAGTGCAACCCAGGCTGCCGACGCCGC
CGTTGTCGCTTCGCTTAAACCGCTTGGGTTTATCGCTTCCGCCATTGCTGATGGCGTTACGGATACGCAAGTATTACTTC
CGGATGGGGCATCCGAGCATGATTATTCATTGCGTCCATCAGACGTAAAACGCTTACAGGGCGCGGACTTAGTCGTCTGG
GTTGGCCCGGAAATGGAAGCCTTTATGGAGAAGTCGGTCAGGAATATTCCTGATAATAAGCAGGTTACCATTGCACAACT
TGCCGATGTAAAACCGTTACTCATGAAGGGCGCGGATGATGATGAGGATGAACATGCGCATACGGGCGCCGATGAGGAAA
AAGGTGACGTACATCACCATCATGGCGAATATAACATGCATCTTTGGCTCTCCCCAGAGATAGCGCGGGCTACAGCGGTT
GCAATCCATGAAAAATTAGTGGAACTTATGCCGCAAAGTCGAGCCAAACTCGACGCCAACCTGAAGGATTTTGAGGCACA
ATTAGCCGCAACCGATAAACAGGTCGGTAACGAGCTCGCGCCGCTCAAGGGGAAAGGGTATTTCGTTTTTCATGACGCCT
ACGGTTACTACGAAAAACACTACGGACTCACCCCACTCGGTCACTTTACCGTGAACCCTGAGATACAACCTGGCGCGCAG
CGTTTACATGAAATAAGAACACAGTTGGTTGAGCAAAAAGCAACCTGCGTTTTTGCTGAGCCACAATTCAGGCCAGCGGT
CGTGGAAGCCGTGGCGAGAGGGACATCCGTTCGAATGGGAACACTGGACCCCCTCGGGACGAACATTAAACTGGGTAAAA
CAAGCTATTCAGCGTTTTTAAGCCAATTAGCCAACCAGTATGCGAGCTGCCTGAAAGGAGATTAA

Upstream 100 bases:

>100_bases
CCAGTGAAACTAAACTTGTCATGTTAATTTTAGGCTTGCAGAAGTGATAGAATGTTATAATATCACATTTCACACATTCA
TTACGATGATTAGTCGCATT

Downstream 100 bases:

>100_bases
CGAGGAAGTGAATACGTGCAACAGATAGCCCGCTCTGTCGCCCTGGCATTTAATAATCTGCCCCGACCCCACCGCGTTAT
GCTGGGGTCACTTACCGTTC

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIADGVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVW
VGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKGADDDEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAV
AIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQ
RLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD

Sequences:

>Translated_314_residues
MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIADGVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVW
VGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKGADDDEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAV
AIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQ
RLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD
>Mature_314_residues
MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIADGVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVW
VGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKGADDDEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAV
AIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQ
RLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=314, Percent_Identity=86.9426751592357, Blast_Score=526, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 34194; Mature: 34194

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIADGVTDTQVLLPDGASEH
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCCCCC
DYSLRPSDVKRLQGADLVVWVGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKGADD
CCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEHHHHHCCCHHHHCCCCC
DEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAVAIHEKLVELMPQSRAKLDAN
CCCHHCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCC
LKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQ
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCEEECCCCCHHHH
RLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFL
HHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCEEECCHHHHHHH
SQLANQYASCLKGD
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIADGVTDTQVLLPDGASEH
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEECCCCCCC
DYSLRPSDVKRLQGADLVVWVGPEMEAFMEKSVRNIPDNKQVTIAQLADVKPLLMKGADD
CCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCEEHHHHHCCCHHHHCCCCC
DEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAVAIHEKLVELMPQSRAKLDAN
CCCHHCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHCCC
LKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYEKHYGLTPLGHFTVNPEIQPGAQ
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCEEECCCCCHHHH
RLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTSVRMGTLDPLGTNIKLGKTSYSAFL
HHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEECCCCCCCCCEEECCHHHHHHH
SQLANQYASCLKGD
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 9600841; 9680209 [H]