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The map label for this gene is ruvB [H]

Identifier: 194735485

GI number: 194735485

Start: 1967617

End: 1968627

Strand: Reverse

Name: ruvB [H]

Synonym: SeSA_A2048

Alternate gene names: 194735485

Gene position: 1968627-1967617 (Counterclockwise)

Preceding gene: 194736016

Following gene: 194734060

Centisome position: 41.8

GC content: 57.37

Gene sequence:

>1011_bases
ATGATAGAAGCAGATCGCCTGATTTCAGCAGGCGCCACGATCGCAGAAGACGTCGCCGATCGCGCCATTCGCCCGAAGTT
ATTGGCGGAATATGTCGGCCAACCGCAGGTGCGCTCCCAGATGGAGATTTTTATTCAGGCGGCAAAACGGCGTGGCGACG
CATTAGATCACTTGCTGATTTTCGGCCCGCCAGGGTTAGGTAAAACGACTCTGGCGAATATCGTTGCCAATGAAATGGGC
GTCAATCTCCGCACCACGTCCGGCCCGGTGCTGGAAAAAGCAGGCGATCTGGCGGCTATGCTCACCAATCTTGAACCGCA
TGATGTGCTGTTTATTGATGAGATTCACCGGCTTTCACCGGTGGTGGAAGAAGTACTCTATCCGGCGATGGAAGATTACC
AGTTGGATATTATGATTGGCGAAGGGCCTGCTGCACGTTCAATTAAAATCGATCTGCCGCCGTTTACGCTCATTGGCGCG
ACGACGCGCGCCGGGTCGTTAACGTCCCCGCTACGCGACCGTTTTGGTATTGTGCAGCGCCTGGAGTTCTACCAGGTGCC
CGATCTGCAGCACATCGTCGGGCGCAGCGCAAGGCACATGGGGCTTGAGATGAGCGATGACGGCGCGCTGGAAGTGGCGC
GTCGGGCGCGCGGTACGCCGCGTATAGCCAACCGCCTGCTCAGACGTGTGCGTGATTTCGCCGAGGTGAAGCATGACGGG
GCTATTTCAGCGGAAATTGCCGCACAGGCGCTGGATATGCTGAACGTCGATGCGGAAGGGTTTGACTATATGGATCGCAA
GCTGCTGCTGGCGGTTATTGATAAATTCTTCGGTGGACCGGTCGGCCTGGATAACCTGGCGGCGGCGATTGGCGAAGAGC
GTGAAACCATTGAGGATGTGCTGGAGCCGTATCTGATTCAGCAAGGCTTTTTGCAGCGCACGCCGCGTGGGCGTATGGCA
ACGGTGCGCGCCTGGAACCATTTCGGGATCACGCCGCCAGAGATGCCTTAG

Upstream 100 bases:

>100_bases
CGCAAGAAGCCAGTCGGATGGTAAGCAAGATCGCCCGTCCGGATGCAAGCAGTGAAACACTGATTCGCGACGCGTTACGC
GCCGCGTTATGAGGTAAAGG

Downstream 100 bases:

>100_bases
CGCCTGAAGTCGCTGCGCTCATCAGACCTGGGCGATTTTGTAGGCCCGGTAAGCGCAGCGCCACCGGGCAACACACGCTT
AGCTTGCCTGCTTTTTCATC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDG
AISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMA
TVRAWNHFGITPPEMP

Sequences:

>Translated_336_residues
MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDG
AISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMA
TVRAWNHFGITPPEMP
>Mature_336_residues
MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDG
AISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMA
TVRAWNHFGITPPEMP

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=336, Percent_Identity=96.4285714285714, Blast_Score=650, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37019; Mature: 37019

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLI
CCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQR
HHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHH
LEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDG
HHHHCCCCHHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDV
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLI
CCCHHHHHHCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEE
FGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSP
ECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHH
VVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQR
HHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHH
LEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDG
HHHHCCCCHHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDV
CHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHH
LEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA