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The map label for this gene is gmr [H]

Identifier: 194734043

GI number: 194734043

Start: 1773928

End: 1775910

Strand: Direct

Name: gmr [H]

Synonym: SeSA_A1831

Alternate gene names: 194734043

Gene position: 1773928-1775910 (Clockwise)

Preceding gene: 194737209

Following gene: 194738074

Centisome position: 37.67

GC content: 50.48

Gene sequence:

>1983_bases
ATGATGAAACAGATTCAGGAACAAACGGCGCTAAGTCCCCTTCACTCTCACTGGCGTCTGGCTGATAACCGCAACGTGCT
GTATCTCTCCCCGACAGGTGAAACGGATGCAGAAAAAACGGTTGAGCTATCGCCGGAACAAGCCGGGCGTATCCGGGAAA
TAACGGCGATTACGTCCAGTCTGCTGATAACGTTGTTGATAGAAAAACAGGTTACCGCTGTGCACCTGGTAGGCCGTAAG
ATTAATAACCGTGAATGGGCTGGCAGCCTGGCAACCTGGCCTGATACGCCTGCCGTCTCGCCAACGCAGGCGCAGGAGCT
CTCTTTTGCCGAGCAAATCGTATCAGAAGCCAACTCAGTCATTGCGATACTGGATAGTCGGGGAAAAATCTGTCGATTTA
ATCGGTTATGCGAAGAGTACACGGGCTTAAAAGAGCAAGATGTAATTGGTCAAAGCGTCTTTAAATTATTTATGAGTCGC
CGGGAGGCGGTTGCCTCCCGGCACTACATTGAGAATTTTTTTCGCAATGGCAATGCCTATGAAATCGAACGCTGGATAAA
GACCCGTAAAGGCCAACGCCTGTTCTTATTTCGTAATAAATTCGTCCATAACGGCAGCGGAAAAAACGAAATTTTCCTGA
TCTGCGCAGGCACGGATATCACCGAAGAAAGGCGGGCTCAGGAGCGTTTACGCATACTGGCGAATACAGACACCGTCACC
GGCCTGCCCAATCGCAATGCTATTCATGAATTTATTAATCATGCTATTGCCTCGGCTGGCGAGTCGCAAGTGGGTATCGT
TTATCTCGATCTGGATAATTTCAAGAAAATTAATGACGCCTATGGGCATATGTTTGGCGATCAGCTCTTACAGGCCGTTT
CGCTGGCGCTGTTGAGTTGTCTGGAGGAAGATCAATTGCTGGCCAGACTGGGGGGAGATGAATTCATTGTTCTCGCTGCC
CATACGTCTCAGGCCGCGCTGGAAGCAGTAGCCTCACGAATCCTTACCCGTCTGCGGCAACCGTTTCGTATTGGACTCAT
TGAAGTTTACACGGGATGCGCCATTGGCATTTCGTTGGCCCCCCGGCACGGACAGGACAGCGAAAGTCTCATTCGCACTG
CCGACACCGCAATGTATAACGCCAAAGAAGGCGGCCGCGGTCAGTTCTGCGTTTTTTCGCCGGAAATGAATCAGCGCGTA
TTTGACTATCACTGGCTGGATACAAACCTGCGAAAAGCGCTGGAAAACGACCAGTTACTTATTCACTATCAGCCCAAAAT
TACCTGGCGCGGCGAAGTACGTAGCCTGGAAGCGCTGGTACGCTGGCAATCGCCGGAACGCGGATTAATTCCGCCGCTGG
AGTTCATCTCATACGCCGAAGAGTCAGGACTCATCGTCCCGCTGGGCCGCTGGGTGATTCTGGATGTGGTTCGCCAGATT
GCGAAATGGCGCGATAAAGGGATTAACTTGCGCGTAGCCGTTAACTTTTCGGCGCGACAACTGGCCGACCAGACGCTTTT
TACTGCGCTTAAACAGGCTTTGTACGATCTGAATTTTGAGTATTGCCCGATCGATGTCGAGCTAACGGAAAGCTGCCTGA
TCGAAAACGACACGCTGGCGCTATCGGTTATCCAGCAATTTAGTCAGCTCGGCGCCCAGATTCATCTGGATGATTTTGGC
ACCGGGTATTCTTCGCTTTCTCAACTCGCCCGGTTCCCTATTGATGCCGTTAAACTGGATCAGGCTTTCGTCAGAGATAT
CCATAAGCAACCGCTGTCGCAATCTCTGGTTAGGGCGATTGTCGCGGTGGCTCAGGCGCTAAATTTACAAGTGATTGCCG
AAGGTGTAGAAAATGCTAAAGAAGATGCCTTCCTGACAAAAAACGGCGTCAATGAACGACAGGGCTTTTTATTCGCCAAA
CCTATGCCCGCCGTTTCTTTTGAACGCTGGTACAAACGTTATCAGACGAAAAAAATGCGTTAA

Upstream 100 bases:

>100_bases
AATACATAGATAAAACAATACGTTCAGCCATAATTACCCTTATTTATAACATGGCTAACCTTTCTTTTCGGGCACCTGGC
GCTTAAATGGGATGGTATGC

Downstream 100 bases:

>100_bases
TGGCGACGATAATAGGGAGAACAGCCTGTGCAGACAGGCATAGCCCTATTTTTCCCTTCTCTTTTCAGATTAATTTCTGC
ATCATGAATTGAAACCTTTT

Product: RNase II stability modulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MMKQIQEQTALSPLHSHWRLADNRNVLYLSPTGETDAEKTVELSPEQAGRIREITAITSSLLITLLIEKQVTAVHLVGRK
INNREWAGSLATWPDTPAVSPTQAQELSFAEQIVSEANSVIAILDSRGKICRFNRLCEEYTGLKEQDVIGQSVFKLFMSR
REAVASRHYIENFFRNGNAYEIERWIKTRKGQRLFLFRNKFVHNGSGKNEIFLICAGTDITEERRAQERLRILANTDTVT
GLPNRNAIHEFINHAIASAGESQVGIVYLDLDNFKKINDAYGHMFGDQLLQAVSLALLSCLEEDQLLARLGGDEFIVLAA
HTSQAALEAVASRILTRLRQPFRIGLIEVYTGCAIGISLAPRHGQDSESLIRTADTAMYNAKEGGRGQFCVFSPEMNQRV
FDYHWLDTNLRKALENDQLLIHYQPKITWRGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVILDVVRQI
AKWRDKGINLRVAVNFSARQLADQTLFTALKQALYDLNFEYCPIDVELTESCLIENDTLALSVIQQFSQLGAQIHLDDFG
TGYSSLSQLARFPIDAVKLDQAFVRDIHKQPLSQSLVRAIVAVAQALNLQVIAEGVENAKEDAFLTKNGVNERQGFLFAK
PMPAVSFERWYKRYQTKKMR

Sequences:

>Translated_660_residues
MMKQIQEQTALSPLHSHWRLADNRNVLYLSPTGETDAEKTVELSPEQAGRIREITAITSSLLITLLIEKQVTAVHLVGRK
INNREWAGSLATWPDTPAVSPTQAQELSFAEQIVSEANSVIAILDSRGKICRFNRLCEEYTGLKEQDVIGQSVFKLFMSR
REAVASRHYIENFFRNGNAYEIERWIKTRKGQRLFLFRNKFVHNGSGKNEIFLICAGTDITEERRAQERLRILANTDTVT
GLPNRNAIHEFINHAIASAGESQVGIVYLDLDNFKKINDAYGHMFGDQLLQAVSLALLSCLEEDQLLARLGGDEFIVLAA
HTSQAALEAVASRILTRLRQPFRIGLIEVYTGCAIGISLAPRHGQDSESLIRTADTAMYNAKEGGRGQFCVFSPEMNQRV
FDYHWLDTNLRKALENDQLLIHYQPKITWRGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVILDVVRQI
AKWRDKGINLRVAVNFSARQLADQTLFTALKQALYDLNFEYCPIDVELTESCLIENDTLALSVIQQFSQLGAQIHLDDFG
TGYSSLSQLARFPIDAVKLDQAFVRDIHKQPLSQSLVRAIVAVAQALNLQVIAEGVENAKEDAFLTKNGVNERQGFLFAK
PMPAVSFERWYKRYQTKKMR
>Mature_660_residues
MMKQIQEQTALSPLHSHWRLADNRNVLYLSPTGETDAEKTVELSPEQAGRIREITAITSSLLITLLIEKQVTAVHLVGRK
INNREWAGSLATWPDTPAVSPTQAQELSFAEQIVSEANSVIAILDSRGKICRFNRLCEEYTGLKEQDVIGQSVFKLFMSR
REAVASRHYIENFFRNGNAYEIERWIKTRKGQRLFLFRNKFVHNGSGKNEIFLICAGTDITEERRAQERLRILANTDTVT
GLPNRNAIHEFINHAIASAGESQVGIVYLDLDNFKKINDAYGHMFGDQLLQAVSLALLSCLEEDQLLARLGGDEFIVLAA
HTSQAALEAVASRILTRLRQPFRIGLIEVYTGCAIGISLAPRHGQDSESLIRTADTAMYNAKEGGRGQFCVFSPEMNQRV
FDYHWLDTNLRKALENDQLLIHYQPKITWRGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVILDVVRQI
AKWRDKGINLRVAVNFSARQLADQTLFTALKQALYDLNFEYCPIDVELTESCLIENDTLALSVIQQFSQLGAQIHLDDFG
TGYSSLSQLARFPIDAVKLDQAFVRDIHKQPLSQSLVRAIVAVAQALNLQVIAEGVENAKEDAFLTKNGVNERQGFLFAK
PMPAVSFERWYKRYQTKKMR

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=657, Percent_Identity=79.2998477929985, Blast_Score=1088, Evalue=0.0,
Organism=Escherichia coli, GI87081921, Length=434, Percent_Identity=34.1013824884793, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI226510982, Length=423, Percent_Identity=31.2056737588652, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=32.2709163346614, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=30.2788844621514, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87081743, Length=246, Percent_Identity=30.8943089430894, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081845, Length=237, Percent_Identity=33.7552742616034, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1788849, Length=433, Percent_Identity=27.2517321016166, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081980, Length=269, Percent_Identity=30.4832713754647, Blast_Score=119, Evalue=9e-28,
Organism=Escherichia coli, GI1787055, Length=299, Percent_Identity=30.7692307692308, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786507, Length=251, Percent_Identity=31.0756972111554, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=426, Percent_Identity=26.7605633802817, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI1788381, Length=551, Percent_Identity=24.6823956442831, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87081977, Length=177, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081881, Length=202, Percent_Identity=31.1881188118812, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=32.7160493827161, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787816, Length=174, Percent_Identity=33.9080459770115, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787410, Length=117, Percent_Identity=34.1880341880342, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=30.5389221556886, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788956, Length=150, Percent_Identity=32, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 74623; Mature: 74623

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKQIQEQTALSPLHSHWRLADNRNVLYLSPTGETDAEKTVELSPEQAGRIREITAITSS
CCHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCCEEECCHHHCCCHHHHHHHHHH
LLITLLIEKQVTAVHLVGRKINNREWAGSLATWPDTPAVSPTQAQELSFAEQIVSEANSV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
IAILDSRGKICRFNRLCEEYTGLKEQDVIGQSVFKLFMSRREAVASRHYIENFFRNGNAY
EEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EIERWIKTRKGQRLFLFRNKFVHNGSGKNEIFLICAGTDITEERRAQERLRILANTDTVT
HHHHHHHHCCCCEEEEEEHHHEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
GLPNRNAIHEFINHAIASAGESQVGIVYLDLDNFKKINDAYGHMFGDQLLQAVSLALLSC
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEDQLLARLGGDEFIVLAAHTSQAALEAVASRILTRLRQPFRIGLIEVYTGCAIGISLA
HHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCCEEEEEEC
PRHGQDSESLIRTADTAMYNAKEGGRGQFCVFSPEMNQRVFDYHWLDTNLRKALENDQLL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEECCHHHHHHHCCCCEE
IHYQPKITWRGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVILDVVRQI
EEECCCEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHH
AKWRDKGINLRVAVNFSARQLADQTLFTALKQALYDLNFEYCPIDVELTESCLIENDTLA
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEHHHHHCCCCHHH
LSVIQQFSQLGAQIHLDDFGTGYSSLSQLARFPIDAVKLDQAFVRDIHKQPLSQSLVRAI
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
VAVAQALNLQVIAEGVENAKEDAFLTKNGVNERQGFLFAKPMPAVSFERWYKRYQTKKMR
HHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MMKQIQEQTALSPLHSHWRLADNRNVLYLSPTGETDAEKTVELSPEQAGRIREITAITSS
CCHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCCCCCCEEECCHHHCCCHHHHHHHHHH
LLITLLIEKQVTAVHLVGRKINNREWAGSLATWPDTPAVSPTQAQELSFAEQIVSEANSV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCE
IAILDSRGKICRFNRLCEEYTGLKEQDVIGQSVFKLFMSRREAVASRHYIENFFRNGNAY
EEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EIERWIKTRKGQRLFLFRNKFVHNGSGKNEIFLICAGTDITEERRAQERLRILANTDTVT
HHHHHHHHCCCCEEEEEEHHHEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCC
GLPNRNAIHEFINHAIASAGESQVGIVYLDLDNFKKINDAYGHMFGDQLLQAVSLALLSC
CCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEDQLLARLGGDEFIVLAAHTSQAALEAVASRILTRLRQPFRIGLIEVYTGCAIGISLA
HHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHCCHHHHHCCCEEEEEEC
PRHGQDSESLIRTADTAMYNAKEGGRGQFCVFSPEMNQRVFDYHWLDTNLRKALENDQLL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCEEEEEECCHHHHHHHCCCCEE
IHYQPKITWRGEVRSLEALVRWQSPERGLIPPLEFISYAEESGLIVPLGRWVILDVVRQI
EEECCCEEECCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHHH
AKWRDKGINLRVAVNFSARQLADQTLFTALKQALYDLNFEYCPIDVELTESCLIENDTLA
HHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEHHHHHCCCCHHH
LSVIQQFSQLGAQIHLDDFGTGYSSLSQLARFPIDAVKLDQAFVRDIHKQPLSQSLVRAI
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHH
VAVAQALNLQVIAEGVENAKEDAFLTKNGVNERQGFLFAKPMPAVSFERWYKRYQTKKMR
HHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]