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The map label for this gene is pyrH [H]

Identifier: 194334607

GI number: 194334607

Start: 1974296

End: 1975021

Strand: Reverse

Name: pyrH [H]

Synonym: Paes_1808

Alternate gene names: 194334607

Gene position: 1975021-1974296 (Counterclockwise)

Preceding gene: 194334608

Following gene: 194334604

Centisome position: 78.59

GC content: 50.28

Gene sequence:

>726_bases
ATGCTTAAATACCGACGCATCCTACTCAAGTTAAGCGGCGAATCTCTTGCCGGAGAAGATGGTTACGGAATCAGTCCTGC
AATGCTTGATCGGTATGCAGAAGAGATTCGTCAGGTACTTGAGCTGGGCGCCGAAATCGCACTTGTGATCGGTGGAGGAA
ATATTTTTCGCGGAATGTCTGCTGCTGCCGAAAATATGGACCGGGTTCAGGCAGACCAGATGGGTATGCTTGCAACGGTG
ATCAACGCCCTTGCCCTGCAGGATGCACTTGAGCGCAAAGGGATCTTTACCCGCCTGATGAGCGCCATCAAAATGGAGCA
GGTTGCTGAGCCTTTTATACGCAGGAGGGCAATCCGTCATCTTGAAAAAGGTCGTGTCGTTATTTTCGGCGCAGGGACAG
GAAACCCCTATTTTACCACTGATACGGCAGCATCCCTTCGCGCTATCGAGATCGAGGCTGATGTTATCATCAAGGGGACG
AGGGTCGATGGCGTGTACGATTCGGATCCTGAGAAAAATCCCGCTGCCGAGATGTACAGCAATATTTCTTATCAGGATGT
GCTCACAAAAAATCTTCGTGTTATGGACCTTACCGCTATTACCCTCTGTCGGGAGAACTTGTTGCCGCTTGTTGTCATGA
ATATGAACATCGAGAACAATTTCTCCAGACTGGTTACGGGTGAAACGGTCGGAACGCTTGTCCATCGCGGTGCCGATTCT
GACTGA

Upstream 100 bases:

>100_bases
GAGCTTTGTGCTTTGCAGTGTCGAGACCATTTCGGGACGAGCGTGCTTCATGGATTGCGTTACAGAGAGAGAATTTTTCT
AAATCACCGGAGGTTCAGAT

Downstream 100 bases:

>100_bases
GCCAGGCTTCAGTTTGTCAGGAGCTCATCGAGCGTTTGTCGAATAGTCTGACTGTCGAAACCTCTGTTGACGAGGTGCGT
ATGCAGTTTTTTCCGTCGAT

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MLKYRRILLKLSGESLAGEDGYGISPAMLDRYAEEIRQVLELGAEIALVIGGGNIFRGMSAAAENMDRVQADQMGMLATV
INALALQDALERKGIFTRLMSAIKMEQVAEPFIRRRAIRHLEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGT
RVDGVYDSDPEKNPAAEMYSNISYQDVLTKNLRVMDLTAITLCRENLLPLVVMNMNIENNFSRLVTGETVGTLVHRGADS
D

Sequences:

>Translated_241_residues
MLKYRRILLKLSGESLAGEDGYGISPAMLDRYAEEIRQVLELGAEIALVIGGGNIFRGMSAAAENMDRVQADQMGMLATV
INALALQDALERKGIFTRLMSAIKMEQVAEPFIRRRAIRHLEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGT
RVDGVYDSDPEKNPAAEMYSNISYQDVLTKNLRVMDLTAITLCRENLLPLVVMNMNIENNFSRLVTGETVGTLVHRGADS
D
>Mature_241_residues
MLKYRRILLKLSGESLAGEDGYGISPAMLDRYAEEIRQVLELGAEIALVIGGGNIFRGMSAAAENMDRVQADQMGMLATV
INALALQDALERKGIFTRLMSAIKMEQVAEPFIRRRAIRHLEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGT
RVDGVYDSDPEKNPAAEMYSNISYQDVLTKNLRVMDLTAITLCRENLLPLVVMNMNIENNFSRLVTGETVGTLVHRGADS
D

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=54.5454545454545, Blast_Score=259, Evalue=1e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26499; Mature: 26499

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYRRILLKLSGESLAGEDGYGISPAMLDRYAEEIRQVLELGAEIALVIGGGNIFRGMS
CCHHHEEHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
AAAENMDRVQADQMGMLATVINALALQDALERKGIFTRLMSAIKMEQVAEPFIRRRAIRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGTRVDGVYDSDPEKNPAAEMYS
HHCCCEEEEECCCCCCCEECCCCCCEEEEEEEEEEEEEECEECCCCCCCCCCCCHHHHHH
NISYQDVLTKNLRVMDLTAITLCRENLLPLVVMNMNIENNFSRLVTGETVGTLVHRGADS
CCCHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHCCCCC
D
C
>Mature Secondary Structure
MLKYRRILLKLSGESLAGEDGYGISPAMLDRYAEEIRQVLELGAEIALVIGGGNIFRGMS
CCHHHEEHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHH
AAAENMDRVQADQMGMLATVINALALQDALERKGIFTRLMSAIKMEQVAEPFIRRRAIRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEKGRVVIFGAGTGNPYFTTDTAASLRAIEIEADVIIKGTRVDGVYDSDPEKNPAAEMYS
HHCCCEEEEECCCCCCCEECCCCCCEEEEEEEEEEEEEECEECCCCCCCCCCCCHHHHHH
NISYQDVLTKNLRVMDLTAITLCRENLLPLVVMNMNIENNFSRLVTGETVGTLVHRGADS
CCCHHHHHHCCCEEEHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCHHHHHHHHCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA