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The map label for this gene is tsf

Identifier: 194334608

GI number: 194334608

Start: 1975195

End: 1976061

Strand: Reverse

Name: tsf

Synonym: Paes_1809

Alternate gene names: 194334608

Gene position: 1976061-1975195 (Counterclockwise)

Preceding gene: 194334609

Following gene: 194334607

Centisome position: 78.64

GC content: 50.52

Gene sequence:

>867_bases
ATGAGTCAGATATCTGCAAAAGATGTAAAAGATTTACGCGATAAAACAGGCGTCGGTATGATGGACTGCAAGAAAGCCCT
GGAGGAAACCGGGGGCGATATGCAGAAGGCCATTGAATACCTTCGCAAAAAAGGTGCTGCGCTGGCAGCAAAGCGTGCCG
GGCGCGAAGCAAGTGAAGGTATTATTGCTATCAGGATCAGCGACGACAACACCTCCGGCGTCATCATAGAACTCAATTGC
GAGACGGACTTTGTTGCTCGCGGCGACGATTTTACCGGTTTCGCTGCTGCTATTGCCGATCTGGCTCTTGAGAACGGTAT
TGCTTCAGCCGAAGCGATGATGTCGCTCAAGCTTGGCGAAGCCTATGGTAACGAGAGTGTCGAAGATTCGATCAAGACAA
TGACAGGCCGGCTTGGCGAGAAAATTGATCTCAAGCGTCTCTCTCTCCTGCAGACCTCGACTGGTATTATTGCCAGCTAC
ATCCATCCCGGATCACAGCTCGGCGCCATTGTCGAACTTGCTACCGATAAACCGGCGGAGTCAGCAGAACTGGCTCGCGA
TATCGCTATGCAGGTTGCAGCATCCTCCCCAATCGTTGTCGATCGTTCAGTCGTACCGGCTGAGAATATCGAAAAAGAGA
AAGAGATTTTCCGTCAGCAGGCACTCAGCCAGGGTAAACCAGAGCAGTTTGTTGAGAAGATCGTTACAGGAAGGCTTGAA
AAGTACTATCAGGAAGTTGTGCTTCTTGAACAGCCATTTATCAAAGACAGCAACTCCCGGGTGCAGGGAGTACTTGAAGA
ATTCGCTCGTAAGAATGGTGCTGCCGTCTCGGTGACTCGATTCGTGCGATATCAGTTAGGAGCGTAA

Upstream 100 bases:

>100_bases
AGGTGATCGAGGCAGAGGCTATGGAAGAAGCCGAAGAAAAGGCAGTGAACGAAGCCGCAGCAGAGTAAGTATATTCTATT
ATTAAACAGACAGAATTGTC

Downstream 100 bases:

>100_bases
ATATGAAAAAGCCTCGTTTTTCGAGGCTTTTTTTTTAGCACGATTCTTCTTGTTGTGTCATACCTCGCTGCTAGAGCTTT
GTGCTTTGCAGTGTCGAGAC

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSQISAKDVKDLRDKTGVGMMDCKKALEETGGDMQKAIEYLRKKGAALAAKRAGREASEGIIAIRISDDNTSGVIIELNC
ETDFVARGDDFTGFAAAIADLALENGIASAEAMMSLKLGEAYGNESVEDSIKTMTGRLGEKIDLKRLSLLQTSTGIIASY
IHPGSQLGAIVELATDKPAESAELARDIAMQVAASSPIVVDRSVVPAENIEKEKEIFRQQALSQGKPEQFVEKIVTGRLE
KYYQEVVLLEQPFIKDSNSRVQGVLEEFARKNGAAVSVTRFVRYQLGA

Sequences:

>Translated_288_residues
MSQISAKDVKDLRDKTGVGMMDCKKALEETGGDMQKAIEYLRKKGAALAAKRAGREASEGIIAIRISDDNTSGVIIELNC
ETDFVARGDDFTGFAAAIADLALENGIASAEAMMSLKLGEAYGNESVEDSIKTMTGRLGEKIDLKRLSLLQTSTGIIASY
IHPGSQLGAIVELATDKPAESAELARDIAMQVAASSPIVVDRSVVPAENIEKEKEIFRQQALSQGKPEQFVEKIVTGRLE
KYYQEVVLLEQPFIKDSNSRVQGVLEEFARKNGAAVSVTRFVRYQLGA
>Mature_287_residues
SQISAKDVKDLRDKTGVGMMDCKKALEETGGDMQKAIEYLRKKGAALAAKRAGREASEGIIAIRISDDNTSGVIIELNCE
TDFVARGDDFTGFAAAIADLALENGIASAEAMMSLKLGEAYGNESVEDSIKTMTGRLGEKIDLKRLSLLQTSTGIIASYI
HPGSQLGAIVELATDKPAESAELARDIAMQVAASSPIVVDRSVVPAENIEKEKEIFRQQALSQGKPEQFVEKIVTGRLEK
YYQEVVLLEQPFIKDSNSRVQGVLEEFARKNGAAVSVTRFVRYQLGA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=219, Percent_Identity=30.5936073059361, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI291084500, Length=239, Percent_Identity=29.2887029288703, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI291084498, Length=92, Percent_Identity=43.4782608695652, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI291084502, Length=84, Percent_Identity=46.4285714285714, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786366, Length=287, Percent_Identity=37.9790940766551, Blast_Score=180, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI17561440, Length=310, Percent_Identity=26.7741935483871, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19921466, Length=244, Percent_Identity=27.8688524590164, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_PROA2 (B4S429)

Other databases:

- EMBL:   CP001108
- RefSeq:   YP_002016468.1
- ProteinModelPortal:   B4S429
- SMR:   B4S429
- GeneID:   6460278
- GenomeReviews:   CP001108_GR
- KEGG:   paa:Paes_1809
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31165; Mature: 31034

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQISAKDVKDLRDKTGVGMMDCKKALEETGGDMQKAIEYLRKKGAALAAKRAGREASEG
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCC
IIAIRISDDNTSGVIIELNCETDFVARGDDFTGFAAAIADLALENGIASAEAMMSLKLGE
EEEEEEECCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AYGNESVEDSIKTMTGRLGEKIDLKRLSLLQTSTGIIASYIHPGSQLGAIVELATDKPAE
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCH
SAELARDIAMQVAASSPIVVDRSVVPAENIEKEKEIFRQQALSQGKPEQFVEKIVTGRLE
HHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KYYQEVVLLEQPFIKDSNSRVQGVLEEFARKNGAAVSVTRFVRYQLGA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCC
>Mature Secondary Structure 
SQISAKDVKDLRDKTGVGMMDCKKALEETGGDMQKAIEYLRKKGAALAAKRAGREASEG
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCC
IIAIRISDDNTSGVIIELNCETDFVARGDDFTGFAAAIADLALENGIASAEAMMSLKLGE
EEEEEEECCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
AYGNESVEDSIKTMTGRLGEKIDLKRLSLLQTSTGIIASYIHPGSQLGAIVELATDKPAE
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCH
SAELARDIAMQVAASSPIVVDRSVVPAENIEKEKEIFRQQALSQGKPEQFVEKIVTGRLE
HHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KYYQEVVLLEQPFIKDSNSRVQGVLEEFARKNGAAVSVTRFVRYQLGA
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA