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The map label for this gene is kamA [H]

Identifier: 194333635

GI number: 194333635

Start: 879484

End: 880797

Strand: Reverse

Name: kamA [H]

Synonym: Paes_0802

Alternate gene names: 194333635

Gene position: 880797-879484 (Counterclockwise)

Preceding gene: 194333636

Following gene: 194333634

Centisome position: 35.05

GC content: 49.24

Gene sequence:

>1314_bases
ATGCCATTATCACCAACTCAGGAACAGATTATCAACTCCATTGACAACGAAGCAACATCATCACACTGGAAAGACTGGAA
GTGGCAGATGCGAAACAGCATCCGCGATCTGGACACCTTTGAAACCCTTCTCAATATTACCCTCTCCCCCGACCAGCGCA
ATGTGTTCAACGAGACGGTAAAAAAGTTTCCGATGTCCATCACGCCCTACTACCTCTCTCTGATAAACACCTCGGATATG
GAGAACGATCCGGTCTTTCGTCAAAGTGTTCCATCCCATCATGAACTTGACATCATGAAAGGCGATATGGCCGACCCTCT
TCATGAAGATCAGGACAGCCCCGCACCTTGTGTCACCCATCGATATCCGGACAGGGTGCTGCTGCTTGTCAGCAATACCT
GCCCCATGTACTGCCGCCACTGCACAAGAAAACGCAAGGTGGGAGATCAGGATACCATCCCCACAAAAACATCAATCAGC
AAAGGGATAGACTACATCCGCAGCAACCCGGCCATCAGAGATGTACTGTTGAGCGGAGGGGATCCGTTTCTGCTGCCCGA
TGACTATCTCGACTGGATTCTTGAGGAACTTCGAAAGATTGAGCATGTCGAAATCATCCGTATCGGCACACGCACGCCAG
TCGTTCTTCCCTATCGTATAACGCCTGAACTGGTTCAAATACTCAGAAAGCATCAGCCGGTATGGGTCAATACCCATTTC
AACCATTCCAGAGAGATGACCCAGTCTGCACGAAACGCACTCAGCATGCTGGCCGATGGCGGAATTCCTCTTGGCAACCA
GACTGTTCTGCTTTCAGGCATCAATGACTGCCCGAGAATCATGAAAGCGCTGGTACACCAGCTCGTAAAAAATCGAGTTC
GTCCTTACTACCTCTACCAGTGCGATCTTTCGGAAGGCTTATCGCACTTCAGAACACCCGTAGGAAAAGGCATCGAAATT
CTTGAAAGTCTTATCGGTCACACCAGCGGATTCTGTGTTCCAACGTATGTCATCGATGCTCCCGGAGGCGGCGGAAAAAT
ACCCGTCATGCCGAACTACCTGATTTCATGGTCTACCAATAAAGTAGTCCTGAGAAATTATGAAGGCGTCATTACAACCT
ATAAGGAACCGGACTCATACGAACCGACCTTCTGTGACAGAAATTGCGATTCATGCGATCTCCTGCTCAAACTCGAAGAC
GCAGATGAAACAAAAGCTATCGGTATCGAGCAGCTCCTCTCCGACCATGACCAGACCATTTCACTTGTTCCTGCCTCAAA
CGCAAGGCATTCACGCCGAAAAGCTGAACAGTAA

Upstream 100 bases:

>100_bases
GACCAATGCACGCTTTCGGAGCTTCTTGAAAAACTCGCCGGACATCTCGACATGCCAGTCGATGATCCCGGCAGCAACCC
TGAAATCAGTTACCCATCCC

Downstream 100 bases:

>100_bases
GCCATTATGAGTAGTGTTGACTATGTGATTTTCGGTATCTACCTGGCTGTAACGCTCTCCATAGGCTTCTATCATTTTCG
TCATAATAAGGGTGAAGAGG

Product: lysine 2,3-aminomutase YodO family protein

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MPLSPTQEQIINSIDNEATSSHWKDWKWQMRNSIRDLDTFETLLNITLSPDQRNVFNETVKKFPMSITPYYLSLINTSDM
ENDPVFRQSVPSHHELDIMKGDMADPLHEDQDSPAPCVTHRYPDRVLLLVSNTCPMYCRHCTRKRKVGDQDTIPTKTSIS
KGIDYIRSNPAIRDVLLSGGDPFLLPDDYLDWILEELRKIEHVEIIRIGTRTPVVLPYRITPELVQILRKHQPVWVNTHF
NHSREMTQSARNALSMLADGGIPLGNQTVLLSGINDCPRIMKALVHQLVKNRVRPYYLYQCDLSEGLSHFRTPVGKGIEI
LESLIGHTSGFCVPTYVIDAPGGGGKIPVMPNYLISWSTNKVVLRNYEGVITTYKEPDSYEPTFCDRNCDSCDLLLKLED
ADETKAIGIEQLLSDHDQTISLVPASNARHSRRKAEQ

Sequences:

>Translated_437_residues
MPLSPTQEQIINSIDNEATSSHWKDWKWQMRNSIRDLDTFETLLNITLSPDQRNVFNETVKKFPMSITPYYLSLINTSDM
ENDPVFRQSVPSHHELDIMKGDMADPLHEDQDSPAPCVTHRYPDRVLLLVSNTCPMYCRHCTRKRKVGDQDTIPTKTSIS
KGIDYIRSNPAIRDVLLSGGDPFLLPDDYLDWILEELRKIEHVEIIRIGTRTPVVLPYRITPELVQILRKHQPVWVNTHF
NHSREMTQSARNALSMLADGGIPLGNQTVLLSGINDCPRIMKALVHQLVKNRVRPYYLYQCDLSEGLSHFRTPVGKGIEI
LESLIGHTSGFCVPTYVIDAPGGGGKIPVMPNYLISWSTNKVVLRNYEGVITTYKEPDSYEPTFCDRNCDSCDLLLKLED
ADETKAIGIEQLLSDHDQTISLVPASNARHSRRKAEQ
>Mature_436_residues
PLSPTQEQIINSIDNEATSSHWKDWKWQMRNSIRDLDTFETLLNITLSPDQRNVFNETVKKFPMSITPYYLSLINTSDME
NDPVFRQSVPSHHELDIMKGDMADPLHEDQDSPAPCVTHRYPDRVLLLVSNTCPMYCRHCTRKRKVGDQDTIPTKTSISK
GIDYIRSNPAIRDVLLSGGDPFLLPDDYLDWILEELRKIEHVEIIRIGTRTPVVLPYRITPELVQILRKHQPVWVNTHFN
HSREMTQSARNALSMLADGGIPLGNQTVLLSGINDCPRIMKALVHQLVKNRVRPYYLYQCDLSEGLSHFRTPVGKGIEIL
ESLIGHTSGFCVPTYVIDAPGGGGKIPVMPNYLISWSTNKVVLRNYEGVITTYKEPDSYEPTFCDRNCDSCDLLLKLEDA
DETKAIGIEQLLSDHDQTISLVPASNARHSRRKAEQ

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=328, Percent_Identity=31.7073170731707, Blast_Score=177, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 49720; Mature: 49589

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSPTQEQIINSIDNEATSSHWKDWKWQMRNSIRDLDTFETLLNITLSPDQRNVFNETV
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHH
KKFPMSITPYYLSLINTSDMENDPVFRQSVPSHHELDIMKGDMADPLHEDQDSPAPCVTH
HHCCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
RYPDRVLLLVSNTCPMYCRHCTRKRKVGDQDTIPTKTSISKGIDYIRSNPAIRDVLLSGG
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
DPFLLPDDYLDWILEELRKIEHVEIIRIGTRTPVVLPYRITPELVQILRKHQPVWVNTHF
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHHHHCCCEEEECCC
NHSREMTQSARNALSMLADGGIPLGNQTVLLSGINDCPRIMKALVHQLVKNRVRPYYLYQ
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
CDLSEGLSHFRTPVGKGIEILESLIGHTSGFCVPTYVIDAPGGGGKIPVMPNYLISWSTN
CCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCC
KVVLRNYEGVITTYKEPDSYEPTFCDRNCDSCDLLLKLEDADETKAIGIEQLLSDHDQTI
EEEEECCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEE
SLVPASNARHSRRKAEQ
EEEECCCCHHHHHCCCC
>Mature Secondary Structure 
PLSPTQEQIINSIDNEATSSHWKDWKWQMRNSIRDLDTFETLLNITLSPDQRNVFNETV
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHH
KKFPMSITPYYLSLINTSDMENDPVFRQSVPSHHELDIMKGDMADPLHEDQDSPAPCVTH
HHCCCCCCHHHHHHHCCCCCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
RYPDRVLLLVSNTCPMYCRHCTRKRKVGDQDTIPTKTSISKGIDYIRSNPAIRDVLLSGG
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCC
DPFLLPDDYLDWILEELRKIEHVEIIRIGTRTPVVLPYRITPELVQILRKHQPVWVNTHF
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCHHHHHHHHHCCCEEEECCC
NHSREMTQSARNALSMLADGGIPLGNQTVLLSGINDCPRIMKALVHQLVKNRVRPYYLYQ
CCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEE
CDLSEGLSHFRTPVGKGIEILESLIGHTSGFCVPTYVIDAPGGGGKIPVMPNYLISWSTN
CCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEECCC
KVVLRNYEGVITTYKEPDSYEPTFCDRNCDSCDLLLKLEDADETKAIGIEQLLSDHDQTI
EEEEECCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEE
SLVPASNARHSRRKAEQ
EEEECCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]