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The map label for this gene is rsmB [H]

Identifier: 194333562

GI number: 194333562

Start: 777037

End: 778386

Strand: Reverse

Name: rsmB [H]

Synonym: Paes_0728

Alternate gene names: 194333562

Gene position: 778386-777037 (Counterclockwise)

Preceding gene: 194333565

Following gene: 194333561

Centisome position: 30.98

GC content: 51.33

Gene sequence:

>1350_bases
ATGCAAAAAAAAACGTCAATAAATGCACGAGAAATAGCACTCCTGACGCTCGTTGAATGTGAACGTGAAGAGGTCAAATC
AGAACAGGCATTACACCGCTATCTCAACAAATACAAAACAGCCCGCAATGACAGCGCCCTTGCGACAGAACTGGTTAACG
GTATCCTTCGATTCCGACAGAGCATCGACAGCATCATCACCGCGTTCTATCATCATAAGCTGAAAAAAGCCTCTCCTTTT
CTGGTCAATATTCTACGGATTGGAGTCTACCAGCTCCGATATCTTGACAGGATTCCTGATTGGGCAGCAGTCAGCCAGTG
TGTCGATCTGGCCAGAAAATACAAAGGGCAGCACATTGCACGCATAGTTAACGGAGTGTTGCGCAGTGTCGCTGCCAATC
CGCAGAAAACAGTCTCATCGCTGGAAATGCAGAACCCGCTGCAGCAGCTTGCCGCAGCAACGTCACATCCGGAATGGATG
CTTGAACGATGGATGGCGCGCTATGGTGAAGATCGTACCAGAAGGGTAACGAGCTATAACAATACCCCGCCCCTCTTCGG
ATTGCGCATCAACACCCTGAAAACAAACAAGGAAGCCATGCTGAAAGCCTTTGCTGACGCATCGGTAGAATTCATTGAAA
CCGGCTTGCCATCGTTCCTTCTGACAAAAGATTTCCACCGTACTGAACCCTTTATCACACTAGGCCTGCTCACAGTGCAG
AACCCTGTTCAGGCTCTGCCATGTCTTCTGCTTGACCCCGAAGAAGGAGAAACCGTTCTCGACATGTGCGCAGCACCAGG
AGGAAAATCAACCTTTCTGGCAGAACTGATGCATAACAGCGGAAAAGTCATTGCCGTCGATCGCTACCCCAACAAATGCC
GTACGATACGTGAGCGTGCCTCTCAGATGGCCATCTCGGTAATTACAACCATCGACAGTGATGCCAGAAACGTTCCTGCC
GGGATAAGCCCTGCAAAAATTCTCCTTGACGCCCCATGCAGCGGCACCGGCGTTCTTGCCCGGCGACCCGAATTGCGATG
GAAAATGAACCGGGAAAAAATCACGCAACTCGTCGCGCTCCAGGAAAGCCTCCTGAATCACGCGGCTACACTGCTTCCTG
CTGGAGGAGTGCTGGTCTATTCAACCTGTTCGATCGAAGAAGAGGAAAACATGCTGCAGATTGATCGTTTTCTGCAGAAA
CACCCTGAATTCATAGCAGAAAGCCATCCCCGTGGCTTGCCGGGGCCCTGCCATGAACTATCAGGACATCCTGGCGCCTA
TCTCACGCTTCCCGGCGATCACGAGGGGTTCGACGGCGGATTTGCCCAGCGATTGAGAAAACAAGCCTGA

Upstream 100 bases:

>100_bases
TATAACATATGGAAACTCACCTGGTCGGACGCCAGCCGCTGCTTAAGTGGAGTCAGTGCGTCCTGCAACGCAGGAATCAA
AGACACTCAGTATAGAACCT

Downstream 100 bases:

>100_bases
AAAGCATGACAAATCTGGAATTCCCCTACATTGACCACCTCGACAGTTTTCTCAACTACCTGACGCTTGAAAGAAACTTC
TCGGTCAATACAAGACAATC

Product: sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQKKTSINAREIALLTLVECEREEVKSEQALHRYLNKYKTARNDSALATELVNGILRFRQSIDSIITAFYHHKLKKASPF
LVNILRIGVYQLRYLDRIPDWAAVSQCVDLARKYKGQHIARIVNGVLRSVAANPQKTVSSLEMQNPLQQLAAATSHPEWM
LERWMARYGEDRTRRVTSYNNTPPLFGLRINTLKTNKEAMLKAFADASVEFIETGLPSFLLTKDFHRTEPFITLGLLTVQ
NPVQALPCLLLDPEEGETVLDMCAAPGGKSTFLAELMHNSGKVIAVDRYPNKCRTIRERASQMAISVITTIDSDARNVPA
GISPAKILLDAPCSGTGVLARRPELRWKMNREKITQLVALQESLLNHAATLLPAGGVLVYSTCSIEEEENMLQIDRFLQK
HPEFIAESHPRGLPGPCHELSGHPGAYLTLPGDHEGFDGGFAQRLRKQA

Sequences:

>Translated_449_residues
MQKKTSINAREIALLTLVECEREEVKSEQALHRYLNKYKTARNDSALATELVNGILRFRQSIDSIITAFYHHKLKKASPF
LVNILRIGVYQLRYLDRIPDWAAVSQCVDLARKYKGQHIARIVNGVLRSVAANPQKTVSSLEMQNPLQQLAAATSHPEWM
LERWMARYGEDRTRRVTSYNNTPPLFGLRINTLKTNKEAMLKAFADASVEFIETGLPSFLLTKDFHRTEPFITLGLLTVQ
NPVQALPCLLLDPEEGETVLDMCAAPGGKSTFLAELMHNSGKVIAVDRYPNKCRTIRERASQMAISVITTIDSDARNVPA
GISPAKILLDAPCSGTGVLARRPELRWKMNREKITQLVALQESLLNHAATLLPAGGVLVYSTCSIEEEENMLQIDRFLQK
HPEFIAESHPRGLPGPCHELSGHPGAYLTLPGDHEGFDGGFAQRLRKQA
>Mature_449_residues
MQKKTSINAREIALLTLVECEREEVKSEQALHRYLNKYKTARNDSALATELVNGILRFRQSIDSIITAFYHHKLKKASPF
LVNILRIGVYQLRYLDRIPDWAAVSQCVDLARKYKGQHIARIVNGVLRSVAANPQKTVSSLEMQNPLQQLAAATSHPEWM
LERWMARYGEDRTRRVTSYNNTPPLFGLRINTLKTNKEAMLKAFADASVEFIETGLPSFLLTKDFHRTEPFITLGLLTVQ
NPVQALPCLLLDPEEGETVLDMCAAPGGKSTFLAELMHNSGKVIAVDRYPNKCRTIRERASQMAISVITTIDSDARNVPA
GISPAKILLDAPCSGTGVLARRPELRWKMNREKITQLVALQESLLNHAATLLPAGGVLVYSTCSIEEEENMLQIDRFLQK
HPEFIAESHPRGLPGPCHELSGHPGAYLTLPGDHEGFDGGFAQRLRKQA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=308, Percent_Identity=31.4935064935065, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI76150623, Length=308, Percent_Identity=31.4935064935065, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI32698918, Length=180, Percent_Identity=38.8888888888889, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI8922322, Length=247, Percent_Identity=29.1497975708502, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI270288818, Length=247, Percent_Identity=29.1497975708502, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI270288816, Length=247, Percent_Identity=29.1497975708502, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI23199998, Length=247, Percent_Identity=29.1497975708502, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI301336155, Length=183, Percent_Identity=31.6939890710383, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI39995082, Length=183, Percent_Identity=31.6939890710383, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI11545785, Length=229, Percent_Identity=30.1310043668122, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI2367212, Length=417, Percent_Identity=31.89448441247, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87081985, Length=278, Percent_Identity=29.8561151079137, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17536757, Length=288, Percent_Identity=29.1666666666667, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71998419, Length=167, Percent_Identity=37.7245508982036, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115534021, Length=167, Percent_Identity=37.7245508982036, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25143471, Length=184, Percent_Identity=34.2391304347826, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=226, Percent_Identity=33.1858407079646, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6319447, Length=208, Percent_Identity=30.2884615384615, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI22024126, Length=227, Percent_Identity=32.5991189427313, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24668781, Length=213, Percent_Identity=34.2723004694836, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI21356513, Length=213, Percent_Identity=34.2723004694836, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI21355201, Length=209, Percent_Identity=30.622009569378, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21356579, Length=193, Percent_Identity=31.0880829015544, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50199; Mature: 50199

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKTSINAREIALLTLVECEREEVKSEQALHRYLNKYKTARNDSALATELVNGILRFRQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SIDSIITAFYHHKLKKASPFLVNILRIGVYQLRYLDRIPDWAAVSQCVDLARKYKGQHIA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
RIVNGVLRSVAANPQKTVSSLEMQNPLQQLAAATSHPEWMLERWMARYGEDRTRRVTSYN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCC
NTPPLFGLRINTLKTNKEAMLKAFADASVEFIETGLPSFLLTKDFHRTEPFITLGLLTVQ
CCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHCCCCEEEEHHHHHC
NPVQALPCLLLDPEEGETVLDMCAAPGGKSTFLAELMHNSGKVIAVDRYPNKCRTIRERA
CHHHHCCEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
SQMAISVITTIDSDARNVPAGISPAKILLDAPCSGTGVLARRPELRWKMNREKITQLVAL
HHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHH
QESLLNHAATLLPAGGVLVYSTCSIEEEENMLQIDRFLQKHPEFIAESHPRGLPGPCHEL
HHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCHHHHHCCCCCCCCCCHHHC
SGHPGAYLTLPGDHEGFDGGFAQRLRKQA
CCCCCEEEECCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MQKKTSINAREIALLTLVECEREEVKSEQALHRYLNKYKTARNDSALATELVNGILRFRQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SIDSIITAFYHHKLKKASPFLVNILRIGVYQLRYLDRIPDWAAVSQCVDLARKYKGQHIA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
RIVNGVLRSVAANPQKTVSSLEMQNPLQQLAAATSHPEWMLERWMARYGEDRTRRVTSYN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCC
NTPPLFGLRINTLKTNKEAMLKAFADASVEFIETGLPSFLLTKDFHRTEPFITLGLLTVQ
CCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHCCCCEEEEHHHHHC
NPVQALPCLLLDPEEGETVLDMCAAPGGKSTFLAELMHNSGKVIAVDRYPNKCRTIRERA
CHHHHCCEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
SQMAISVITTIDSDARNVPAGISPAKILLDAPCSGTGVLARRPELRWKMNREKITQLVAL
HHHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCCCCCCCCCCCCHHHHCCHHHHHHHHHH
QESLLNHAATLLPAGGVLVYSTCSIEEEENMLQIDRFLQKHPEFIAESHPRGLPGPCHEL
HHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCHHHHHCCCCCCCCCCHHHC
SGHPGAYLTLPGDHEGFDGGFAQRLRKQA
CCCCCEEEECCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]