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The map label for this gene is xerD [H]

Identifier: 194333561

GI number: 194333561

Start: 776117

End: 777031

Strand: Reverse

Name: xerD [H]

Synonym: Paes_0727

Alternate gene names: 194333561

Gene position: 777031-776117 (Counterclockwise)

Preceding gene: 194333562

Following gene: 194333554

Centisome position: 30.92

GC content: 48.96

Gene sequence:

>915_bases
ATGACAAATCTGGAATTCCCCTACATTGACCACCTCGACAGTTTTCTCAACTACCTGACGCTTGAAAGAAACTTCTCGGT
CAATACAAGACAATCCTATACCAACGACCTCAGCCGTTACCTGCTCTACATGCAGCAGCAGCAAAAGGCTGTCGAATCAA
TCAAACTCGATGACATCAGAGAGTTTATCCATACCCTCTCAGCAACAGGCATGGAAGCTCGCTCGATAGCAAGAAACATT
TCAGCCATACGCTCACTGCACAAATTTCTCGTAGCCGAAAAAATCGTTCAGGTCAATGAAACCAACAATCTTCGTCAGCC
GAAACCGCTCAAAGCGCTGCCGAAAGTTCTTACGCACGACGAAGCCTTCAAACTGCTTGACGCCCCTCTGGCAAAGGACT
CATCAAGCCGTTATGCTCTTCGCGATAAAGCTATACTGGAATTTCTCTACGCAACCGGGGTGAGGGTCAGCGAACTGGTC
GACGTGTGCCAGAACAACTGTTTTCTTGATGAGGGATTCATTCGCATTTTCGGCAAAGGATCAAAAGAGCGTCTGGTCCC
GATAGGCTCCTCTGCTGTCTCCTGGATCAAACGATATCTGGATGAACTTCGAATGCGCATTGCCAACGATCGATCCGCTG
ACTTTCTTTTTCTCAATGCCAGAGGAGGCAGACTGACCAGAATGACGGTGTACAATATCGTGACCCACTACAGCCTCATT
GCAGGAATAAGCAAAACTATCAGCCCACATACACTTCGCCACACGTTTGCGACTCACCTGCTGGAAGGAGGTGCTGACCT
TCGCGCTGTTCAGGAAATGCTGGGTCACAGCTCCATTCTGGCCACGCAGATCTATACCCACATCGACCGAAGCTTCCTCT
GTGAAGTCCACAAGTCCTTCCATCCAAGAGGATAA

Upstream 100 bases:

>100_bases
AACTATCAGGACATCCTGGCGCCTATCTCACGCTTCCCGGCGATCACGAGGGGTTCGACGGCGGATTTGCCCAGCGATTG
AGAAAACAAGCCTGAAAAGC

Downstream 100 bases:

>100_bases
TGAGCCTTGCCCTGTCAATTACTCTGCAAAGCGCTGAATCGTGAATCATCAGGCAGGAGCCAGATCGAAAATCTCCCCCG
GTCCGGGAATGATCACATCA

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTNLEFPYIDHLDSFLNYLTLERNFSVNTRQSYTNDLSRYLLYMQQQQKAVESIKLDDIREFIHTLSATGMEARSIARNI
SAIRSLHKFLVAEKIVQVNETNNLRQPKPLKALPKVLTHDEAFKLLDAPLAKDSSSRYALRDKAILEFLYATGVRVSELV
DVCQNNCFLDEGFIRIFGKGSKERLVPIGSSAVSWIKRYLDELRMRIANDRSADFLFLNARGGRLTRMTVYNIVTHYSLI
AGISKTISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQIYTHIDRSFLCEVHKSFHPRG

Sequences:

>Translated_304_residues
MTNLEFPYIDHLDSFLNYLTLERNFSVNTRQSYTNDLSRYLLYMQQQQKAVESIKLDDIREFIHTLSATGMEARSIARNI
SAIRSLHKFLVAEKIVQVNETNNLRQPKPLKALPKVLTHDEAFKLLDAPLAKDSSSRYALRDKAILEFLYATGVRVSELV
DVCQNNCFLDEGFIRIFGKGSKERLVPIGSSAVSWIKRYLDELRMRIANDRSADFLFLNARGGRLTRMTVYNIVTHYSLI
AGISKTISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQIYTHIDRSFLCEVHKSFHPRG
>Mature_303_residues
TNLEFPYIDHLDSFLNYLTLERNFSVNTRQSYTNDLSRYLLYMQQQQKAVESIKLDDIREFIHTLSATGMEARSIARNIS
AIRSLHKFLVAEKIVQVNETNNLRQPKPLKALPKVLTHDEAFKLLDAPLAKDSSSRYALRDKAILEFLYATGVRVSELVD
VCQNNCFLDEGFIRIFGKGSKERLVPIGSSAVSWIKRYLDELRMRIANDRSADFLFLNARGGRLTRMTVYNIVTHYSLIA
GISKTISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQIYTHIDRSFLCEVHKSFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=42.1768707482993, Blast_Score=233, Evalue=9e-63,
Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=35.3741496598639, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1790768, Length=147, Percent_Identity=34.0136054421769, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34748; Mature: 34617

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLEFPYIDHLDSFLNYLTLERNFSVNTRQSYTNDLSRYLLYMQQQQKAVESIKLDDIR
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EFIHTLSATGMEARSIARNISAIRSLHKFLVAEKIVQVNETNNLRQPKPLKALPKVLTHD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCH
EAFKLLDAPLAKDSSSRYALRDKAILEFLYATGVRVSELVDVCQNNCFLDEGFIRIFGKG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCHHEEECCC
SKERLVPIGSSAVSWIKRYLDELRMRIANDRSADFLFLNARGGRLTRMTVYNIVTHYSLI
CCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHH
AGISKTISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQIYTHIDRSFLCEVHKSF
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
HPRG
CCCC
>Mature Secondary Structure 
TNLEFPYIDHLDSFLNYLTLERNFSVNTRQSYTNDLSRYLLYMQQQQKAVESIKLDDIR
CCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EFIHTLSATGMEARSIARNISAIRSLHKFLVAEKIVQVNETNNLRQPKPLKALPKVLTHD
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCH
EAFKLLDAPLAKDSSSRYALRDKAILEFLYATGVRVSELVDVCQNNCFLDEGFIRIFGKG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCHHEEECCC
SKERLVPIGSSAVSWIKRYLDELRMRIANDRSADFLFLNARGGRLTRMTVYNIVTHYSLI
CCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHH
AGISKTISPHTLRHTFATHLLEGGADLRAVQEMLGHSSILATQIYTHIDRSFLCEVHKSF
HHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
HPRG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]