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The map label for this gene is waaA [H]

Identifier: 194333554

GI number: 194333554

Start: 767507

End: 768781

Strand: Reverse

Name: waaA [H]

Synonym: Paes_0720

Alternate gene names: 194333554

Gene position: 768781-767507 (Counterclockwise)

Preceding gene: 194333561

Following gene: 194333553

Centisome position: 30.59

GC content: 50.51

Gene sequence:

>1275_bases
ATGAGTGTTCTTGTTATCCTGTATTCCATATTCTTCCCCTTTCTGACGGGAGCCGCACGCCTTGCCGCACTCGGTTCACC
GAAAATCAGGACATATTTTACGTTGCGTAAAGATCTTATAGCGCAGATAGAACAAAAACTCTACGCCCATCAGTGCCCTT
CATTCTGCGTGTGGGTTCATGCTGCATCCGTCGGTGAATTTGAACAGGCAAGACCGGTTATCGAACGGCTGAAGCAACAA
GACCCTGCGTGCAGTATCGTCATCTCATTCCAGTCCCCTTCCGGCTACAATATCCGTAAAGATTACCCGCAAGCCGACGC
GGTTTTCTATCACCCTGTTGATTCACCGGGCAATGCCCGAAAGCTGGTAAAACTGCTCAAACCCGATATCGTCATGATCA
TGCGCTATGATTTCTGGCTCAACCACCTGCTTGCAGCCAGGAAATACGGCGCAAAACTGATTCTGGTCGGCGCAGTCCTG
CAGGACCATTCAATCTATTTCAAACCCCTCGTCAACAGATTCTATCGGCAAGTGTTTCAGCTTTTCGATCAAATCTGTAC
AGTCACGGAAAACGACCGCCAAAAATTTGCACGCACCTTCGGCACCAACAAAGCGCTCACCGCCGGAGATCCGCGCTTCG
ACCAGGTATGGAACCGAAGCCGTAACAGGAAAGAACAGCAGAAGCTCAAGTCGCTCTACAGAGGAAAAACGGTTCTGGTT
GCAGGCAGCACCTGGGCAAAAGACGAGGAAATACTGCTTACCGCATACCTGCAGGCTCATGACAATCTGAGCCTTATCAT
GGTGCCGCATGAAACAGACGCGAACAACATCCATCGAATCGAAACAGATCTCCTCTCACACGACATCGACTACCATCTTC
TGACGAAACTGCCGGAGGACTTCTCCCCCGCATCGGTTCTTGTCGTCGATGCAATCGGTTTGCTTGTCGAACTCTATGCA
CTTGCCGACATTGCCTATGTGGGAGGTGGATTCGGAATCAATGTACACAACACACTTGAACCTGCGGTCTACGGCATCCC
CGTCCTGTTCGGCCCGAATCATCACAATTCGCCTGAGGCCGAAGCGCTTATAGCACTCAAAGGCGCAACAGAAATCCGCA
ACGAATCTGAACTTGAACAGGCAATCAGGCATTTGCTTTCCGATACAGAACAACGAAAAAAGCAGGGAGAAATAGCCGGC
AGGTACGTCAGTGAAAGACTTGGCGCAACAGAGACCATCACCCGGATGATCATGGAACTGGCAAGAGCGTCTTAA

Upstream 100 bases:

>100_bases
CGGCAAAACGAAACAAAGCCTTTTCTGCACAATTTTTTTACTGCTTGATATTTCCGCATTTTGGTCATAGCTTCACCTCT
CAAACCATGGTTATGATCCG

Downstream 100 bases:

>100_bases
CAGCTTATTTCTTATATTTGCCCAATTGATTACCACCAACAAGATTTAAAACGTCACCACTCATGCTTGCAAGAATTCAA
ACGCTCTATCTTGTCATCGC

Product: Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSVLVILYSIFFPFLTGAARLAALGSPKIRTYFTLRKDLIAQIEQKLYAHQCPSFCVWVHAASVGEFEQARPVIERLKQQ
DPACSIVISFQSPSGYNIRKDYPQADAVFYHPVDSPGNARKLVKLLKPDIVMIMRYDFWLNHLLAARKYGAKLILVGAVL
QDHSIYFKPLVNRFYRQVFQLFDQICTVTENDRQKFARTFGTNKALTAGDPRFDQVWNRSRNRKEQQKLKSLYRGKTVLV
AGSTWAKDEEILLTAYLQAHDNLSLIMVPHETDANNIHRIETDLLSHDIDYHLLTKLPEDFSPASVLVVDAIGLLVELYA
LADIAYVGGGFGINVHNTLEPAVYGIPVLFGPNHHNSPEAEALIALKGATEIRNESELEQAIRHLLSDTEQRKKQGEIAG
RYVSERLGATETITRMIMELARAS

Sequences:

>Translated_424_residues
MSVLVILYSIFFPFLTGAARLAALGSPKIRTYFTLRKDLIAQIEQKLYAHQCPSFCVWVHAASVGEFEQARPVIERLKQQ
DPACSIVISFQSPSGYNIRKDYPQADAVFYHPVDSPGNARKLVKLLKPDIVMIMRYDFWLNHLLAARKYGAKLILVGAVL
QDHSIYFKPLVNRFYRQVFQLFDQICTVTENDRQKFARTFGTNKALTAGDPRFDQVWNRSRNRKEQQKLKSLYRGKTVLV
AGSTWAKDEEILLTAYLQAHDNLSLIMVPHETDANNIHRIETDLLSHDIDYHLLTKLPEDFSPASVLVVDAIGLLVELYA
LADIAYVGGGFGINVHNTLEPAVYGIPVLFGPNHHNSPEAEALIALKGATEIRNESELEQAIRHLLSDTEQRKKQGEIAG
RYVSERLGATETITRMIMELARAS
>Mature_423_residues
SVLVILYSIFFPFLTGAARLAALGSPKIRTYFTLRKDLIAQIEQKLYAHQCPSFCVWVHAASVGEFEQARPVIERLKQQD
PACSIVISFQSPSGYNIRKDYPQADAVFYHPVDSPGNARKLVKLLKPDIVMIMRYDFWLNHLLAARKYGAKLILVGAVLQ
DHSIYFKPLVNRFYRQVFQLFDQICTVTENDRQKFARTFGTNKALTAGDPRFDQVWNRSRNRKEQQKLKSLYRGKTVLVA
GSTWAKDEEILLTAYLQAHDNLSLIMVPHETDANNIHRIETDLLSHDIDYHLLTKLPEDFSPASVLVVDAIGLLVELYAL
ADIAYVGGGFGINVHNTLEPAVYGIPVLFGPNHHNSPEAEALIALKGATEIRNESELEQAIRHLLSDTEQRKKQGEIAGR
YVSERLGATETITRMIMELARAS

Specific function: Transfers three 3-deoxy-D-mono octulonic acid (KDO) individually from CMP-KDO to a tetraacyldisaccharide 1,4'- bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=382, Percent_Identity=25.6544502617801, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 47910; Mature: 47778

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVILYSIFFPFLTGAARLAALGSPKIRTYFTLRKDLIAQIEQKLYAHQCPSFCVWVH
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
AASVGEFEQARPVIERLKQQDPACSIVISFQSPSGYNIRKDYPQADAVFYHPVDSPGNAR
CCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHH
KLVKLLKPDIVMIMRYDFWLNHLLAARKYGAKLILVGAVLQDHSIYFKPLVNRFYRQVFQ
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHH
LFDQICTVTENDRQKFARTFGTNKALTAGDPRFDQVWNRSRNRKEQQKLKSLYRGKTVLV
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEE
AGSTWAKDEEILLTAYLQAHDNLSLIMVPHETDANNIHRIETDLLSHDIDYHLLTKLPED
ECCCCCCCCCEEEEEEHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHCCCC
FSPASVLVVDAIGLLVELYALADIAYVGGGFGINVHNTLEPAVYGIPVLFGPNHHNSPEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHCEEEEECCCCCCCCCH
EALIALKGATEIRNESELEQAIRHLLSDTEQRKKQGEIAGRYVSERLGATETITRMIMEL
HEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ARAS
HHCC
>Mature Secondary Structure 
SVLVILYSIFFPFLTGAARLAALGSPKIRTYFTLRKDLIAQIEQKLYAHQCPSFCVWVH
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
AASVGEFEQARPVIERLKQQDPACSIVISFQSPSGYNIRKDYPQADAVFYHPVDSPGNAR
CCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHH
KLVKLLKPDIVMIMRYDFWLNHLLAARKYGAKLILVGAVLQDHSIYFKPLVNRFYRQVFQ
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHH
LFDQICTVTENDRQKFARTFGTNKALTAGDPRFDQVWNRSRNRKEQQKLKSLYRGKTVLV
HHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEE
AGSTWAKDEEILLTAYLQAHDNLSLIMVPHETDANNIHRIETDLLSHDIDYHLLTKLPED
ECCCCCCCCCEEEEEEHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHCCCC
FSPASVLVVDAIGLLVELYALADIAYVGGGFGINVHNTLEPAVYGIPVLFGPNHHNSPEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHCEEEEECCCCCCCCCH
EALIALKGATEIRNESELEQAIRHLLSDTEQRKKQGEIAGRYVSERLGATETITRMIMEL
HEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ARAS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]