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The map label for this gene is trpB-1 [H]

Identifier: 194333507

GI number: 194333507

Start: 715039

End: 716241

Strand: Reverse

Name: trpB-1 [H]

Synonym: Paes_0673

Alternate gene names: 194333507

Gene position: 716241-715039 (Counterclockwise)

Preceding gene: 194333509

Following gene: 194333505

Centisome position: 28.5

GC content: 53.95

Gene sequence:

>1203_bases
ATGACACAACACCCATATTCTGCTCCTGACGCATCCGGCCATTTCGGAACCTACGGAGGCAAATTCATACCCGAAACGCT
TGTAAAAAACGCTGCCGACCTGGAAAAAGAATACCAGAAAGCAAGACAGGACGACCAGTTCTGGCATGAGTACAACACCC
TGCTGAGCCAGTATGTCGGTCGCGCTACCCCGCTCTACCATGCTGAAAACCTATCGAAGAAAACAGGCGGTGCAAAAATC
TTCCTCAAACGAGAAGATCTCTGCCACACCGGAGCGCATAAAATCAACAACGCACTCGGCCAGGCTCTGCTCGCTCGCAG
AATGGGGAAAAAGAGAATAATAGCTGAAACAGGAGCAGGTCAGCATGGGGTCGCGACCGCGACGGTCTGCGCCCTCTTCA
ACCTGGACTGCATCGTCTACATGGGCCAGGAGGACATGAAACGCCAGGCGCCCAACGTCGCAAGAATGAAACTGCTCGGC
GCCGACGTCAGACCCGTTACCAACGGCAGCCGCACCCTCAAAGATGCAACAAGCCAAGCCATCAGGGACTGGATCAACAA
CCCCGAAGAAACGTTCTACATCATCGGTTCAGTCGTCGGCATGCACCCCTACCCGATGATGGTCAGGGATTTTCAGTCGA
TTATCGGAAAAGAGACAAAACAGCAGATACTCCAGCAGACCGGCAAACTTCCTGACGTCATTGCCGCCTGTGTCGGCGGA
GGAAGCAACGCGATCGGCATGTTCTACGAATTTCTCCCCGACGCCCGCCAGATAGAACTTGTGGGGGTCGAAGCTGCCGG
AGAAGGCCTCACCGGACTGAATGCCGCATCCCTCACCCTTGGAAAAACAGGAGTGCTCCACGGAGCAATGATGAAAATTC
TTCAGGATAATTACGGACAAATCAGCGAAGCTCACTCAATTTCTGCAGGTCTTGATTACCCCGGCGTAGGACCGGAACAC
TGCCATCTGCAGGATCTCGGACTGGTCACCTATACCTCGGCAACAGACCAGGAAGCCCTCGCAGCACTGCAAACACTTGC
AAAAACCGAAGGCATCATCTGCGCCCTCGAATCAGCCCACGCCATCCATTACGGCATCACCAGAGCCGCGAAAATGACCC
CAGACCAGACCATCATCGTCAATCTGTCAGGCAGAGGAGACAAAGACATGGAAACGATCATGCGAGAAATCCGTCTGGAC
TGA

Upstream 100 bases:

>100_bases
GAAATTTGGTTTTTGAGGGGAGTGTATCGATAAAATGACAAATATATTATTTTAATGTACGCATGCATCTTCTTTTTCCC
TGTAAATCTTGTCCGTTTTT

Downstream 100 bases:

>100_bases
TTTTTTTCAAAAACTTTTAACAAAAATTTGGTTAAAAACACTAAAAGCCATATAATAGGACACTCTCAAGCGGGAATAGC
TCAGCTGGTAGAGCACAACC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQHPYSAPDASGHFGTYGGKFIPETLVKNAADLEKEYQKARQDDQFWHEYNTLLSQYVGRATPLYHAENLSKKTGGAKI
FLKREDLCHTGAHKINNALGQALLARRMGKKRIIAETGAGQHGVATATVCALFNLDCIVYMGQEDMKRQAPNVARMKLLG
ADVRPVTNGSRTLKDATSQAIRDWINNPEETFYIIGSVVGMHPYPMMVRDFQSIIGKETKQQILQQTGKLPDVIAACVGG
GSNAIGMFYEFLPDARQIELVGVEAAGEGLTGLNAASLTLGKTGVLHGAMMKILQDNYGQISEAHSISAGLDYPGVGPEH
CHLQDLGLVTYTSATDQEALAALQTLAKTEGIICALESAHAIHYGITRAAKMTPDQTIIVNLSGRGDKDMETIMREIRLD

Sequences:

>Translated_400_residues
MTQHPYSAPDASGHFGTYGGKFIPETLVKNAADLEKEYQKARQDDQFWHEYNTLLSQYVGRATPLYHAENLSKKTGGAKI
FLKREDLCHTGAHKINNALGQALLARRMGKKRIIAETGAGQHGVATATVCALFNLDCIVYMGQEDMKRQAPNVARMKLLG
ADVRPVTNGSRTLKDATSQAIRDWINNPEETFYIIGSVVGMHPYPMMVRDFQSIIGKETKQQILQQTGKLPDVIAACVGG
GSNAIGMFYEFLPDARQIELVGVEAAGEGLTGLNAASLTLGKTGVLHGAMMKILQDNYGQISEAHSISAGLDYPGVGPEH
CHLQDLGLVTYTSATDQEALAALQTLAKTEGIICALESAHAIHYGITRAAKMTPDQTIIVNLSGRGDKDMETIMREIRLD
>Mature_399_residues
TQHPYSAPDASGHFGTYGGKFIPETLVKNAADLEKEYQKARQDDQFWHEYNTLLSQYVGRATPLYHAENLSKKTGGAKIF
LKREDLCHTGAHKINNALGQALLARRMGKKRIIAETGAGQHGVATATVCALFNLDCIVYMGQEDMKRQAPNVARMKLLGA
DVRPVTNGSRTLKDATSQAIRDWINNPEETFYIIGSVVGMHPYPMMVRDFQSIIGKETKQQILQQTGKLPDVIAACVGGG
SNAIGMFYEFLPDARQIELVGVEAAGEGLTGLNAASLTLGKTGVLHGAMMKILQDNYGQISEAHSISAGLDYPGVGPEHC
HLQDLGLVTYTSATDQEALAALQTLAKTEGIICALESAHAIHYGITRAAKMTPDQTIIVNLSGRGDKDMETIMREIRLD

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=383, Percent_Identity=50.6527415143603, Blast_Score=388, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321412, Length=381, Percent_Identity=53.5433070866142, Blast_Score=427, Evalue=1e-120,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43459; Mature: 43328

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQHPYSAPDASGHFGTYGGKFIPETLVKNAADLEKEYQKARQDDQFWHEYNTLLSQYVG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RATPLYHAENLSKKTGGAKIFLKREDLCHTGAHKINNALGQALLARRMGKKRIIAETGAG
CCCCCHHHHHCHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
QHGVATATVCALFNLDCIVYMGQEDMKRQAPNVARMKLLGADVRPVTNGSRTLKDATSQA
CCCHHHHHHHHHHCCCEEEEECCHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IRDWINNPEETFYIIGSVVGMHPYPMMVRDFQSIIGKETKQQILQQTGKLPDVIAACVGG
HHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCC
GSNAIGMFYEFLPDARQIELVGVEAAGEGLTGLNAASLTLGKTGVLHGAMMKILQDNYGQ
CCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHEECCCHHHHHHHHHHHHHHCCCC
ISEAHSISAGLDYPGVGPEHCHLQDLGLVTYTSATDQEALAALQTLAKTEGIICALESAH
HHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCC
AIHYGITRAAKMTPDQTIIVNLSGRGDKDMETIMREIRLD
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TQHPYSAPDASGHFGTYGGKFIPETLVKNAADLEKEYQKARQDDQFWHEYNTLLSQYVG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RATPLYHAENLSKKTGGAKIFLKREDLCHTGAHKINNALGQALLARRMGKKRIIAETGAG
CCCCCHHHHHCHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
QHGVATATVCALFNLDCIVYMGQEDMKRQAPNVARMKLLGADVRPVTNGSRTLKDATSQA
CCCHHHHHHHHHHCCCEEEEECCHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
IRDWINNPEETFYIIGSVVGMHPYPMMVRDFQSIIGKETKQQILQQTGKLPDVIAACVGG
HHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHCC
GSNAIGMFYEFLPDARQIELVGVEAAGEGLTGLNAASLTLGKTGVLHGAMMKILQDNYGQ
CCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHEECCCHHHHHHHHHHHHHHCCCC
ISEAHSISAGLDYPGVGPEHCHLQDLGLVTYTSATDQEALAALQTLAKTEGIICALESAH
HHHHHHCCCCCCCCCCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCC
AIHYGITRAAKMTPDQTIIVNLSGRGDKDMETIMREIRLD
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]