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The map label for this gene is yaeL [C]

Identifier: 194332967

GI number: 194332967

Start: 124185

End: 125546

Strand: Reverse

Name: yaeL [C]

Synonym: Paes_0120

Alternate gene names: 194332967

Gene position: 125546-124185 (Counterclockwise)

Preceding gene: 194332968

Following gene: 194332966

Centisome position: 5.0

GC content: 51.76

Gene sequence:

>1362_bases
ATGGATTTTTTGAGTACGACGTTTTATTTCATCATTGCCATTTTCATTCTTGTCACCGTGCATGAGCTCGGTCACTTTCT
GACAGCCAAGCTTTTTGGTATGCGGGTCGACAAGTTTTATATCGGCTTCGACTTCTACAACCTGCGCTTCTGGAAAAAAC
AGATCGGCGAAACAGAATACGGTATCGGCGTGTTTCCGCTCGGCGGTTATGTCAAGATCGCCGGCATGGTCGATGAAAGC
CTTGACACCGATTTTCAGGAAAAAGATCCGGAACCATGGGAGTTCCGCGCAAAACCGGTCTGGCAGCGCCTGATCGTACT
CGCCGGCGGTGTTGTTATGAACATGGTACTTGCTGCCGCGATCTTTATCGGTATGGCCTCTGTTTTCGGCGAAAGCAGGA
CATCGACCCTCAACCCCGCCTATGTAGCAAAGGGTTCGGTCTATGAGGCAATGGGCATGCAGACGGGCGACAGGTTTGTA
AGCGTCAACGGCAAACAGGTTTCCTACTGGGAAGACGTCCTTGCTCCCGAAACATTTGCCGCAGGAAGTCTGCAGTACGT
TGTCAGGCGAAACGGGACGAACATCACCATACCGGCGCCTCAGGACATTCTTACCCGCATTAATGACAGCCAGGCCCTCG
GCATCCGTCCGCTCATGCCTCCGGTCATCGACCAGGTACTTGAAAACCAGCCGGCAGCCGAAGCCGGACTGAAGCCTGGA
GCGCTCATCACGGCAATCGACGCCACACCGGTCAATGACTGGTCAGAGGTTGTCGCTCTGATTTCAGAAAACCCGGGAAA
ACAGATTACCGTCAACTGGAAATATCTCGATCCAGCCGCAGACGGCACGGTCAATGTCGACAAGATCCGTCAGTCAGGCA
TTGCCGAAAGCGCTGAGGTCATCCCGTCGGATATGGGCAGGATCGGCATCGCGCTCAAGCAGACACTATCTATCGATCAC
AGAAAACTCAACCCTGTCGAAGCGACGTTTTATGGCATCGAACAGACCTGGAAAATGACAAGTACAACAGTCATGGGATT
CGGCAAAATCCTGACCGGTAAAGAAGACTTCCGCAAATCCATGGGTGGACCGATCAAGATCGCCAGAATTGCCAACCAGA
GCGCCGAGCAGGGCATAAGCAGCTTTCTCTACTTTGTCGCACTGCTCTCGATCTCGCTCGCATTCATCAATATTCTGCCT
ATTCCGGCGCTTGACGGAGGACAATTTGTCATGAACGCAGTCGAAGGGGTCATGGGACGGGAGATCCCCATTACAATCAA
AATGCGAATACAGCAAGTCGGCATGGCACTCTTACTGACGCTCTTCATGTTCTTCATCATTAATGATATCATTAACCCTT
AA

Upstream 100 bases:

>100_bases
AACGGCTAAAGCCTTTCGACAGTTATATGAGAGAAATATCCCGAACGCTGCATAAAAAGCGGCATTCGGGATAGTTTATG
TTAGCGAAAACCGAACCACC

Downstream 100 bases:

>100_bases
CCGGACCGGAAGACACCGCCATTATTCATGCTGAATAAACTCGAATCAGCAAAAGACCACTATATCCGTCTTGAAGAACA
GCTCTCCGATCCGGACATCA

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDFLSTTFYFIIAIFILVTVHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKQIGETEYGIGVFPLGGYVKIAGMVDES
LDTDFQEKDPEPWEFRAKPVWQRLIVLAGGVVMNMVLAAAIFIGMASVFGESRTSTLNPAYVAKGSVYEAMGMQTGDRFV
SVNGKQVSYWEDVLAPETFAAGSLQYVVRRNGTNITIPAPQDILTRINDSQALGIRPLMPPVIDQVLENQPAAEAGLKPG
ALITAIDATPVNDWSEVVALISENPGKQITVNWKYLDPAADGTVNVDKIRQSGIAESAEVIPSDMGRIGIALKQTLSIDH
RKLNPVEATFYGIEQTWKMTSTTVMGFGKILTGKEDFRKSMGGPIKIARIANQSAEQGISSFLYFVALLSISLAFINILP
IPALDGGQFVMNAVEGVMGREIPITIKMRIQQVGMALLLTLFMFFIINDIINP

Sequences:

>Translated_453_residues
MDFLSTTFYFIIAIFILVTVHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKQIGETEYGIGVFPLGGYVKIAGMVDES
LDTDFQEKDPEPWEFRAKPVWQRLIVLAGGVVMNMVLAAAIFIGMASVFGESRTSTLNPAYVAKGSVYEAMGMQTGDRFV
SVNGKQVSYWEDVLAPETFAAGSLQYVVRRNGTNITIPAPQDILTRINDSQALGIRPLMPPVIDQVLENQPAAEAGLKPG
ALITAIDATPVNDWSEVVALISENPGKQITVNWKYLDPAADGTVNVDKIRQSGIAESAEVIPSDMGRIGIALKQTLSIDH
RKLNPVEATFYGIEQTWKMTSTTVMGFGKILTGKEDFRKSMGGPIKIARIANQSAEQGISSFLYFVALLSISLAFINILP
IPALDGGQFVMNAVEGVMGREIPITIKMRIQQVGMALLLTLFMFFIINDIINP
>Mature_453_residues
MDFLSTTFYFIIAIFILVTVHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKQIGETEYGIGVFPLGGYVKIAGMVDES
LDTDFQEKDPEPWEFRAKPVWQRLIVLAGGVVMNMVLAAAIFIGMASVFGESRTSTLNPAYVAKGSVYEAMGMQTGDRFV
SVNGKQVSYWEDVLAPETFAAGSLQYVVRRNGTNITIPAPQDILTRINDSQALGIRPLMPPVIDQVLENQPAAEAGLKPG
ALITAIDATPVNDWSEVVALISENPGKQITVNWKYLDPAADGTVNVDKIRQSGIAESAEVIPSDMGRIGIALKQTLSIDH
RKLNPVEATFYGIEQTWKMTSTTVMGFGKILTGKEDFRKSMGGPIKIARIANQSAEQGISSFLYFVALLSISLAFINILP
IPALDGGQFVMNAVEGVMGREIPITIKMRIQQVGMALLLTLFMFFIINDIINP

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=461, Percent_Identity=30.8026030368764, Blast_Score=169, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49890; Mature: 49890

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLSTTFYFIIAIFILVTVHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKQIGETEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHCCCCCC
GIGVFPLGGYVKIAGMVDESLDTDFQEKDPEPWEFRAKPVWQRLIVLAGGVVMNMVLAAA
CEEEEECCCEEEEEEHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IFIGMASVFGESRTSTLNPAYVAKGSVYEAMGMQTGDRFVSVNGKQVSYWEDVLAPETFA
HHHHHHHHHCCCCCCCCCCHHEECCCHHHHHCCCCCCEEEEECCCEEHHHHHHCCCCCCC
AGSLQYVVRRNGTNITIPAPQDILTRINDSQALGIRPLMPPVIDQVLENQPAAEAGLKPG
CCCEEEEEEECCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCC
ALITAIDATPVNDWSEVVALISENPGKQITVNWKYLDPAADGTVNVDKIRQSGIAESAEV
CEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCHHHHHHCCCCHHHHH
IPSDMGRIGIALKQTLSIDHRKLNPVEATFYGIEQTWKMTSTTVMGFGKILTGKEDFRKS
CHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHH
MGGPIKIARIANQSAEQGISSFLYFVALLSISLAFINILPIPALDGGQFVMNAVEGVMGR
CCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
EIPITIKMRIQQVGMALLLTLFMFFIINDIINP
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFLSTTFYFIIAIFILVTVHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKQIGETEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHCCCCCC
GIGVFPLGGYVKIAGMVDESLDTDFQEKDPEPWEFRAKPVWQRLIVLAGGVVMNMVLAAA
CEEEEECCCEEEEEEHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IFIGMASVFGESRTSTLNPAYVAKGSVYEAMGMQTGDRFVSVNGKQVSYWEDVLAPETFA
HHHHHHHHHCCCCCCCCCCHHEECCCHHHHHCCCCCCEEEEECCCEEHHHHHHCCCCCCC
AGSLQYVVRRNGTNITIPAPQDILTRINDSQALGIRPLMPPVIDQVLENQPAAEAGLKPG
CCCEEEEEEECCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHHCCCCC
ALITAIDATPVNDWSEVVALISENPGKQITVNWKYLDPAADGTVNVDKIRQSGIAESAEV
CEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCHHHHHHCCCCHHHHH
IPSDMGRIGIALKQTLSIDHRKLNPVEATFYGIEQTWKMTSTTVMGFGKILTGKEDFRKS
CHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHH
MGGPIKIARIANQSAEQGISSFLYFVALLSISLAFINILPIPALDGGQFVMNAVEGVMGR
CCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
EIPITIKMRIQQVGMALLLTLFMFFIINDIINP
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]