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The map label for this gene is kch [C]

Identifier: 194332964

GI number: 194332964

Start: 121211

End: 122248

Strand: Reverse

Name: kch [C]

Synonym: Paes_0117

Alternate gene names: 194332964

Gene position: 122248-121211 (Counterclockwise)

Preceding gene: 194332965

Following gene: 194332963

Centisome position: 4.86

GC content: 52.79

Gene sequence:

>1038_bases
TTGGCAAAGGACACCCAACAGTTCATCACGCTTCGCCGCTTTTCGATATCCATCGTCAGCGTGGTCCTGCTCATCTGGGC
CGGAACAACCGGATATATGATCATCGAACACATGACTCCGGTTGATGCCCTCTATATGACCGTCATCACGCTCAGTACGG
TCGGGTTCAGCGAAATCCACACGCTGTCGGAAAGCGGACGCATCTTCACCTTAGCTTTGATTATCGGCGGAACCAGTTTA
TTTTTCTTTACGTTAAGCAATGTCGCTGTCTTCTTTTTGTCAGGCGAATGGCGATCTCACTGGGAACTTCAACGAAATAT
CCGCATGCTCCGCAAGCTCAACGACCACTTCATTATCTGCGGCTACGGGCGCCTCGGGACCAATGTCGCAACAGAACTGC
AGGAAAAGGGCATCCCCTTCGTCATCATCGATACGACCATCGAAAAAATTCTTCTGGCAAGGGACCTCGGCTACGTCGCC
CTCAAGGGAAACGCCGCTGACGAAACCGTTCTGAAAGACGCCGGTCTGGATAAAGCCAGGGGCCTGATCGCCGCAGCCAA
TACCGATGCTGAAAATGTTTTTATCGTCCTCACAGCAAGAACCCTCAAACCCGGCCTGCATATTGTAGCCCGCGCAGACT
GCGAAGAGTCGGAAAACAAACTGCTCAGAGCGGGAGCTGAACGCGTCGTACTGCTCTATAAATCCGCAGGCAGAAAAATG
GCGAACCTTCTCATCGACCCCGGCCTGGAAGAGTACCTCGACGAACTCAACGACGCAAAAAACCTCGACCTCACCATGTC
GCAGTTCTCTGTCAGCGAGAGTTCTTCGCTCTGTGGCCTCTCGTTCAGGCAAGCCGACATCTACAATCGCTTCCGGGTCA
ACATTATCGGCTACAAGCTGCCCGGAGGAGAGATCCATACAAGCCCTATACCTGCCGAGGTCATCCAGAAAAACGGCATC
CTGATTGCTATCGGCAAACCTTCGGACATCGACGCACTCAAACAGTTCGCCGCAGGAGAAGAGGTAAAGACAGGTTGA

Upstream 100 bases:

>100_bases
GATAAAATGTTCAAAAGCATTTCTAAAGACTTCCGCCCGATTCAACAGGCCTGAAGCCGACCGACGGGAATCCCCGATAA
CCAAACATCATCACGCTTCA

Downstream 100 bases:

>100_bases
TTTGCTGAACTGTTGAAAACTCAACCGCAAAACTGAAAAAAACCATGGACTTTTACGATCTCGTTTCGAGTCGCTCAAGC
CTCAGAAGCTTCATCAAAGA

Product: TrkA-N domain-containing protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: MjK1 [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MAKDTQQFITLRRFSISIVSVVLLIWAGTTGYMIIEHMTPVDALYMTVITLSTVGFSEIHTLSESGRIFTLALIIGGTSL
FFFTLSNVAVFFLSGEWRSHWELQRNIRMLRKLNDHFIICGYGRLGTNVATELQEKGIPFVIIDTTIEKILLARDLGYVA
LKGNAADETVLKDAGLDKARGLIAAANTDAENVFIVLTARTLKPGLHIVARADCEESENKLLRAGAERVVLLYKSAGRKM
ANLLIDPGLEEYLDELNDAKNLDLTMSQFSVSESSSLCGLSFRQADIYNRFRVNIIGYKLPGGEIHTSPIPAEVIQKNGI
LIAIGKPSDIDALKQFAAGEEVKTG

Sequences:

>Translated_345_residues
MAKDTQQFITLRRFSISIVSVVLLIWAGTTGYMIIEHMTPVDALYMTVITLSTVGFSEIHTLSESGRIFTLALIIGGTSL
FFFTLSNVAVFFLSGEWRSHWELQRNIRMLRKLNDHFIICGYGRLGTNVATELQEKGIPFVIIDTTIEKILLARDLGYVA
LKGNAADETVLKDAGLDKARGLIAAANTDAENVFIVLTARTLKPGLHIVARADCEESENKLLRAGAERVVLLYKSAGRKM
ANLLIDPGLEEYLDELNDAKNLDLTMSQFSVSESSSLCGLSFRQADIYNRFRVNIIGYKLPGGEIHTSPIPAEVIQKNGI
LIAIGKPSDIDALKQFAAGEEVKTG
>Mature_344_residues
AKDTQQFITLRRFSISIVSVVLLIWAGTTGYMIIEHMTPVDALYMTVITLSTVGFSEIHTLSESGRIFTLALIIGGTSLF
FFTLSNVAVFFLSGEWRSHWELQRNIRMLRKLNDHFIICGYGRLGTNVATELQEKGIPFVIIDTTIEKILLARDLGYVAL
KGNAADETVLKDAGLDKARGLIAAANTDAENVFIVLTARTLKPGLHIVARADCEESENKLLRAGAERVVLLYKSAGRKMA
NLLIDPGLEEYLDELNDAKNLDLTMSQFSVSESSSLCGLSFRQADIYNRFRVNIIGYKLPGGEIHTSPIPAEVIQKNGIL
IAIGKPSDIDALKQFAAGEEVKTG

Specific function: Potassium channel protein. Seems to conduct potassium at low membrane potentials [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=215, Percent_Identity=30.2325581395349, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786685, Length=133, Percent_Identity=33.0827067669173, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003280
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 37957; Mature: 37826

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDTQQFITLRRFSISIVSVVLLIWAGTTGYMIIEHMTPVDALYMTVITLSTVGFSEIH
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHH
TLSESGRIFTLALIIGGTSLFFFTLSNVAVFFLSGEWRSHWELQRNIRMLRKLNDHFIIC
HHCCCCCEEEEEEECCCCHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
GYGRLGTNVATELQEKGIPFVIIDTTIEKILLARDLGYVALKGNAADETVLKDAGLDKAR
ECCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCHHC
GLIAAANTDAENVFIVLTARTLKPGLHIVARADCEESENKLLRAGAERVVLLYKSAGRKM
CEEEEECCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCHHH
ANLLIDPGLEEYLDELNDAKNLDLTMSQFSVSESSSLCGLSFRQADIYNRFRVNIIGYKL
HHHHCCCCHHHHHHHHCCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHCCEEEEEEEEEEC
PGGEIHTSPIPAEVIQKNGILIAIGKPSDIDALKQFAAGEEVKTG
CCCCEECCCCCHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKDTQQFITLRRFSISIVSVVLLIWAGTTGYMIIEHMTPVDALYMTVITLSTVGFSEIH
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHH
TLSESGRIFTLALIIGGTSLFFFTLSNVAVFFLSGEWRSHWELQRNIRMLRKLNDHFIIC
HHCCCCCEEEEEEECCCCHHEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEE
GYGRLGTNVATELQEKGIPFVIIDTTIEKILLARDLGYVALKGNAADETVLKDAGLDKAR
ECCCCCCHHHHHHHHCCCCEEEECHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCHHC
GLIAAANTDAENVFIVLTARTLKPGLHIVARADCEESENKLLRAGAERVVLLYKSAGRKM
CEEEEECCCCCCEEEEEEEECCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCHHH
ANLLIDPGLEEYLDELNDAKNLDLTMSQFSVSESSSLCGLSFRQADIYNRFRVNIIGYKL
HHHHCCCCHHHHHHHHCCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHCCEEEEEEEEEEC
PGGEIHTSPIPAEVIQKNGILIAIGKPSDIDALKQFAAGEEVKTG
CCCCEECCCCCHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]