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The map label for this gene is trkH [H]

Identifier: 194332954

GI number: 194332954

Start: 107904

End: 109361

Strand: Reverse

Name: trkH [H]

Synonym: Paes_0107

Alternate gene names: 194332954

Gene position: 109361-107904 (Counterclockwise)

Preceding gene: 194332955

Following gene: 194332951

Centisome position: 4.35

GC content: 52.61

Gene sequence:

>1458_bases
ATGAACTTTCCTGCCATTGCCAACGTTCTCGGAACGCTGCTCATGTTTATCGGCAGCACCATGCTGATTCCTCTGGCATG
CGCCCTCATCTATAACGAAGGGGATGCGTTGTCTTTCATGCTTGCGATGATGATCACTATCGGGCTGGCCTTTCCTCTTT
GGTGGTTTTTTCGCCGACAGCGCAACCTGACGATCCGCGACGGATTCTTTATCGTCTCGGTTGGCTGGATCCTGGTATCG
GCCGTCTCGTCACTGCCCTTTATGATCCACGGTTCCATCCCGTCATTTACCGATGCGTTCTTCGAAATGATGTCGGGCTA
TACAACCACCGGAGCAACCATTCTCAATGATGTTGAAGCACTCCCGCACGGACTGCTCTTCTGGCGCAGTATGACACACC
TGATCGGAGGCATGGGGTTCATCATGGTCACCATCATTATCCTGCCGCTCCTGGGCATCGGCGGCATGCAGCTTTACAAG
GCGGAAGCCGACCCCGGACAGGTCATCACGGGAGAAAAATTTCTTCCCCGCGTCAAAGAGGCCGCCATATGGCTCTGGGC
TATCTACCTCGCACTCATCCTCATACAATCGCTGCTCATGTGGGTCGCAGGCATGCCCCTTTTTGACTCGCTCTGCCACG
CTTTCGGCACCGTATCGACATCGGGCTACTCCACAAAAAACAGTAGTATCGGCTACTTCAACAACGCATGGATCGACTGG
ATCACCACAATCTTCATGCTTCTCGGGGGTATGACGTTCATGCTCCATTACCAGATCATCAAACGGGACTGGGAACCGGT
CAAACAGAATACGGAATTTCGATGGTATGGGGGATTCGTCCTCTTTTTCTGTCTCGTGACGACACTGCTGCTTTTTGCCT
CGCCACAGTACGACAACATTTTCGACTCAGCACGTTTCGCCACATTCCAGATCGTCTCCATCCTGACCACAACCGGCTTT
ACCACGACGGATTACGAAGTATGGCCGCAGGCTGCGCAAATGTTCATCCTGATCGTCTGCTTTATCGGCGCCTGTGCCGG
ATCGACCACAAGCGGCATCAAGATTGTGCACTATGAAATCATCAGTAAATACCTCTATGCCACAGGGAAAAAACTCATGC
AGCCCATGGCGGTGGTCCCGGTCAGAATCAATGGACGCATTGCCGAACAACCGGTCATAACCCTGGCGGTCAGCTATTTT
ATCATCAACATCTTCATGGTCTTCATCGGTGCCGCTGTCCTGACGATCTGCGACGACATGGACCTCTTCAGCTCGATGAC
CGCAGTCATCGCAACCCTGTTCAATATCGGACCTGGTTTCGGTGATGTCGGCCCGACACACACCTTTGCGCATATATCGG
AGATCGGCAAGTGGTTTTTATCCTTCAACATGCTTACCGGCCGCCTCGAAATGTTCTCCGTGCTGGTCATGTTCTATCCG
TCATTCTGGAAAGGGTGA

Upstream 100 bases:

>100_bases
CGAGCCCAATGAACGCGCAATTGTCGTTTCAGCAACCAGAAGCCTGAAAGACGCGCAGCAACTCTTTCAGTAACCTCCCG
TTTGAGAGAACCCTGACTGT

Downstream 100 bases:

>100_bases
TCCCGCTTTGCGCATCACGATGACCGGAACCGCCTGACAAGCCCTTCATACGTCCTGTCGAGATTGAACAGAAGATTCAG
AAGAACGGCGAGAATGGTCG

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNFPAIANVLGTLLMFIGSTMLIPLACALIYNEGDALSFMLAMMITIGLAFPLWWFFRRQRNLTIRDGFFIVSVGWILVS
AVSSLPFMIHGSIPSFTDAFFEMMSGYTTTGATILNDVEALPHGLLFWRSMTHLIGGMGFIMVTIIILPLLGIGGMQLYK
AEADPGQVITGEKFLPRVKEAAIWLWAIYLALILIQSLLMWVAGMPLFDSLCHAFGTVSTSGYSTKNSSIGYFNNAWIDW
ITTIFMLLGGMTFMLHYQIIKRDWEPVKQNTEFRWYGGFVLFFCLVTTLLLFASPQYDNIFDSARFATFQIVSILTTTGF
TTTDYEVWPQAAQMFILIVCFIGACAGSTTSGIKIVHYEIISKYLYATGKKLMQPMAVVPVRINGRIAEQPVITLAVSYF
IINIFMVFIGAAVLTICDDMDLFSSMTAVIATLFNIGPGFGDVGPTHTFAHISEIGKWFLSFNMLTGRLEMFSVLVMFYP
SFWKG

Sequences:

>Translated_485_residues
MNFPAIANVLGTLLMFIGSTMLIPLACALIYNEGDALSFMLAMMITIGLAFPLWWFFRRQRNLTIRDGFFIVSVGWILVS
AVSSLPFMIHGSIPSFTDAFFEMMSGYTTTGATILNDVEALPHGLLFWRSMTHLIGGMGFIMVTIIILPLLGIGGMQLYK
AEADPGQVITGEKFLPRVKEAAIWLWAIYLALILIQSLLMWVAGMPLFDSLCHAFGTVSTSGYSTKNSSIGYFNNAWIDW
ITTIFMLLGGMTFMLHYQIIKRDWEPVKQNTEFRWYGGFVLFFCLVTTLLLFASPQYDNIFDSARFATFQIVSILTTTGF
TTTDYEVWPQAAQMFILIVCFIGACAGSTTSGIKIVHYEIISKYLYATGKKLMQPMAVVPVRINGRIAEQPVITLAVSYF
IINIFMVFIGAAVLTICDDMDLFSSMTAVIATLFNIGPGFGDVGPTHTFAHISEIGKWFLSFNMLTGRLEMFSVLVMFYP
SFWKG
>Mature_485_residues
MNFPAIANVLGTLLMFIGSTMLIPLACALIYNEGDALSFMLAMMITIGLAFPLWWFFRRQRNLTIRDGFFIVSVGWILVS
AVSSLPFMIHGSIPSFTDAFFEMMSGYTTTGATILNDVEALPHGLLFWRSMTHLIGGMGFIMVTIIILPLLGIGGMQLYK
AEADPGQVITGEKFLPRVKEAAIWLWAIYLALILIQSLLMWVAGMPLFDSLCHAFGTVSTSGYSTKNSSIGYFNNAWIDW
ITTIFMLLGGMTFMLHYQIIKRDWEPVKQNTEFRWYGGFVLFFCLVTTLLLFASPQYDNIFDSARFATFQIVSILTTTGF
TTTDYEVWPQAAQMFILIVCFIGACAGSTTSGIKIVHYEIISKYLYATGKKLMQPMAVVPVRINGRIAEQPVITLAVSYF
IINIFMVFIGAAVLTICDDMDLFSSMTAVIATLFNIGPGFGDVGPTHTFAHISEIGKWFLSFNMLTGRLEMFSVLVMFYP
SFWKG

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=488, Percent_Identity=38.7295081967213, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1787626, Length=485, Percent_Identity=34.2268041237113, Blast_Score=255, Evalue=4e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 54170; Mature: 54170

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPAIANVLGTLLMFIGSTMLIPLACALIYNEGDALSFMLAMMITIGLAFPLWWFFRRQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RNLTIRDGFFIVSVGWILVSAVSSLPFMIHGSIPSFTDAFFEMMSGYTTTGATILNDVEA
CCCEEECCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
LPHGLLFWRSMTHLIGGMGFIMVTIIILPLLGIGGMQLYKAEADPGQVITGEKFLPRVKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCHHHHHHHHH
AAIWLWAIYLALILIQSLLMWVAGMPLFDSLCHAFGTVSTSGYSTKNSSIGYFNNAWIDW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
ITTIFMLLGGMTFMLHYQIIKRDWEPVKQNTEFRWYGGFVLFFCLVTTLLLFASPQYDNI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHH
FDSARFATFQIVSILTTTGFTTTDYEVWPQAAQMFILIVCFIGACAGSTTSGIKIVHYEI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
ISKYLYATGKKLMQPMAVVPVRINGRIAEQPVITLAVSYFIINIFMVFIGAAVLTICDDM
HHHHHHHHHHHHHCCHHEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLFSSMTAVIATLFNIGPGFGDVGPTHTFAHISEIGKWFLSFNMLTGRLEMFSVLVMFYP
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFWKG
HHCCC
>Mature Secondary Structure
MNFPAIANVLGTLLMFIGSTMLIPLACALIYNEGDALSFMLAMMITIGLAFPLWWFFRRQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RNLTIRDGFFIVSVGWILVSAVSSLPFMIHGSIPSFTDAFFEMMSGYTTTGATILNDVEA
CCCEEECCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
LPHGLLFWRSMTHLIGGMGFIMVTIIILPLLGIGGMQLYKAEADPGQVITGEKFLPRVKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCHHHHHHHHH
AAIWLWAIYLALILIQSLLMWVAGMPLFDSLCHAFGTVSTSGYSTKNSSIGYFNNAWIDW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
ITTIFMLLGGMTFMLHYQIIKRDWEPVKQNTEFRWYGGFVLFFCLVTTLLLFASPQYDNI
HHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCHH
FDSARFATFQIVSILTTTGFTTTDYEVWPQAAQMFILIVCFIGACAGSTTSGIKIVHYEI
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
ISKYLYATGKKLMQPMAVVPVRINGRIAEQPVITLAVSYFIINIFMVFIGAAVLTICDDM
HHHHHHHHHHHHHCCHHEEEEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
DLFSSMTAVIATLFNIGPGFGDVGPTHTFAHISEIGKWFLSFNMLTGRLEMFSVLVMFYP
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFWKG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]