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The map label for this gene is trkA [H]

Identifier: 194332955

GI number: 194332955

Start: 109389

End: 110777

Strand: Reverse

Name: trkA [H]

Synonym: Paes_0108

Alternate gene names: 194332955

Gene position: 110777-109389 (Counterclockwise)

Preceding gene: 194332956

Following gene: 194332954

Centisome position: 4.41

GC content: 52.77

Gene sequence:

>1389_bases
ATGAGCGTCAGGAATATTCTCATTATCGGCCTGGGCGGGGTCGGCCTTCACCTTGCAAGGCGTCTGGTACAGGAAGGTTA
CGGTGTCACCGTCATTGAATCGATTCAGCACCTCATCAGCGCTGCAAACGACAACCTTGACGCCAAGATTATCGACGGCA
ACGCCATGGAGCTGTCGAGCTGGAAACGGGCCCAGGCTGAAAGCATGGATCTGATGATCGCCGTCACGGACCAGGATTCC
GTCAATATGATCGCATCCATCATTGCCGATCGCTTTGGCATCCCACGAAAAATAGCCCGCGTCCGCTCACCGGAATACGG
CTATGACAATTCATTGCTCAACAAAAACGACTTCAAAATCGATCTGGTTATCCACCCCGAAGAGCTGATCGCTCGCGAGA
TAGCCCGTCTCGTGATGCGCTCGTCGGGAAACGATGTCATCGATATCGGCGAAGGGACCATGAAAGTTTGCGCCCTTCGC
GTCAATGCCGCATGCCCTATAGCAAACAGAACTATCGGTGAAATCAGATTGCTGCACAATGAATTCCCTTTCAGGGTCGT
AGCGATTGCCCGCGGCATCAACACCATCATTCCCGGAGACGACGACACTATCATGCCGAATGATCAGGTCTTCATTATGG
TCAATGGGGCTTATCTGTCCCGCCTTATGCAGCTCCTGGGAATGAAGGAACAGACCATCCAGAGGGTCATGATCGTCGGT
GGCGGCATGGTCGGCGCGCGTGTTGCCGAGCTGCTGTGCAAAACCGTCCGGATCAACCTGATTGAATCCGACCAGCAGCA
TGCCGAAGAACTCGCACTTTCGCTGAAAAATACTGATGTTCTGCATGGTGACGGCACCGATGTCAACGTTATGGTCCTCG
GCGGCCTGATGGAAATGGATATTTTCATTGCAACAACGGGCAACAACGAAACCAATATCATCAGCTGCCTCCTTGCCAAA
CATATGATGAACAGGACCAACGTCGATCCCGCAGGCAAGGAAGGAAAAACCATCGCGCTGGTCAAGAAAGAGGACTATCT
GGTGCTGGCCTCGACCATCGGACTCGATATCGCCCTGAACATGAAAATTTCTGCGGCCAACGAAATCATGAAATTTATCC
GCATAGGTGAACTGCTTTCTGTAGCTCATCTGCACGGAGTCGACGCCGAAGTCATTGAGCTGGTCGCTGCCGATCGCTCA
CCGATCACGAAAAAACGCCTTGGCAAACTCCGTTCGACGCTTCAGGACAAAGGCATCCTTGTTGCGGGCATCATCACCAA
CGGCACCTGCATCCTGACCGACGACGACACCCTTATCGAGCCCAATGAACGCGCAATTGTCGTTTCAGCAACCAGAAGCC
TGAAAGACGCGCAGCAACTCTTTCAGTAA

Upstream 100 bases:

>100_bases
TCTCCTGTCATGTTGAGATATATTTTTTTAGATTACCCTATTAATTGAAGAGACGGTATCCTGACCGTTATTTTTTTCCG
TGATTTTGGAGTTATTGCGC

Downstream 100 bases:

>100_bases
CCTCCCGTTTGAGAGAACCCTGACTGTATGAACTTTCCTGCCATTGCCAACGTTCTCGGAACGCTGCTCATGTTTATCGG
CAGCACCATGCTGATTCCTC

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSVRNILIIGLGGVGLHLARRLVQEGYGVTVIESIQHLISAANDNLDAKIIDGNAMELSSWKRAQAESMDLMIAVTDQDS
VNMIASIIADRFGIPRKIARVRSPEYGYDNSLLNKNDFKIDLVIHPEELIAREIARLVMRSSGNDVIDIGEGTMKVCALR
VNAACPIANRTIGEIRLLHNEFPFRVVAIARGINTIIPGDDDTIMPNDQVFIMVNGAYLSRLMQLLGMKEQTIQRVMIVG
GGMVGARVAELLCKTVRINLIESDQQHAEELALSLKNTDVLHGDGTDVNVMVLGGLMEMDIFIATTGNNETNIISCLLAK
HMMNRTNVDPAGKEGKTIALVKKEDYLVLASTIGLDIALNMKISAANEIMKFIRIGELLSVAHLHGVDAEVIELVAADRS
PITKKRLGKLRSTLQDKGILVAGIITNGTCILTDDDTLIEPNERAIVVSATRSLKDAQQLFQ

Sequences:

>Translated_462_residues
MSVRNILIIGLGGVGLHLARRLVQEGYGVTVIESIQHLISAANDNLDAKIIDGNAMELSSWKRAQAESMDLMIAVTDQDS
VNMIASIIADRFGIPRKIARVRSPEYGYDNSLLNKNDFKIDLVIHPEELIAREIARLVMRSSGNDVIDIGEGTMKVCALR
VNAACPIANRTIGEIRLLHNEFPFRVVAIARGINTIIPGDDDTIMPNDQVFIMVNGAYLSRLMQLLGMKEQTIQRVMIVG
GGMVGARVAELLCKTVRINLIESDQQHAEELALSLKNTDVLHGDGTDVNVMVLGGLMEMDIFIATTGNNETNIISCLLAK
HMMNRTNVDPAGKEGKTIALVKKEDYLVLASTIGLDIALNMKISAANEIMKFIRIGELLSVAHLHGVDAEVIELVAADRS
PITKKRLGKLRSTLQDKGILVAGIITNGTCILTDDDTLIEPNERAIVVSATRSLKDAQQLFQ
>Mature_461_residues
SVRNILIIGLGGVGLHLARRLVQEGYGVTVIESIQHLISAANDNLDAKIIDGNAMELSSWKRAQAESMDLMIAVTDQDSV
NMIASIIADRFGIPRKIARVRSPEYGYDNSLLNKNDFKIDLVIHPEELIAREIARLVMRSSGNDVIDIGEGTMKVCALRV
NAACPIANRTIGEIRLLHNEFPFRVVAIARGINTIIPGDDDTIMPNDQVFIMVNGAYLSRLMQLLGMKEQTIQRVMIVGG
GMVGARVAELLCKTVRINLIESDQQHAEELALSLKNTDVLHGDGTDVNVMVLGGLMEMDIFIATTGNNETNIISCLLAKH
MMNRTNVDPAGKEGKTIALVKKEDYLVLASTIGLDIALNMKISAANEIMKFIRIGELLSVAHLHGVDAEVIELVAADRSP
ITKKRLGKLRSTLQDKGILVAGIITNGTCILTDDDTLIEPNERAIVVSATRSLKDAQQLFQ

Specific function: Part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Peripherally bound to the inner side of the inner membrane via the trkG and trkH proteins (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=463, Percent_Identity=28.9416846652268, Blast_Score=198, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50418; Mature: 50286

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRNILIIGLGGVGLHLARRLVQEGYGVTVIESIQHLISAANDNLDAKIIDGNAMELSS
CCCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEHHH
WKRAQAESMDLMIAVTDQDSVNMIASIIADRFGIPRKIARVRSPEYGYDNSLLNKNDFKI
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCEE
DLVIHPEELIAREIARLVMRSSGNDVIDIGEGTMKVCALRVNAACPIANRTIGEIRLLHN
EEEECCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCCCCCCHHHEEEECC
EFPFRVVAIARGINTIIPGDDDTIMPNDQVFIMVNGAYLSRLMQLLGMKEQTIQRVMIVG
CCCEEEEEECCCCCEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHEEEEEC
GGMVGARVAELLCKTVRINLIESDQQHAEELALSLKNTDVLHGDGTDVNVMVLGGLMEMD
CCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCEEEECCCCCEEEEEECCEEEEE
IFIATTGNNETNIISCLLAKHMMNRTNVDPAGKEGKTIALVKKEDYLVLASTIGLDIALN
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCEEEEEE
MKISAANEIMKFIRIGELLSVAHLHGVDAEVIELVAADRSPITKKRLGKLRSTLQDKGIL
EEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEE
VAGIITNGTCILTDDDTLIEPNERAIVVSATRSLKDAQQLFQ
EEEEEECCEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHC
>Mature Secondary Structure 
SVRNILIIGLGGVGLHLARRLVQEGYGVTVIESIQHLISAANDNLDAKIIDGNAMELSS
CCCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCEEHHH
WKRAQAESMDLMIAVTDQDSVNMIASIIADRFGIPRKIARVRSPEYGYDNSLLNKNDFKI
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCEE
DLVIHPEELIAREIARLVMRSSGNDVIDIGEGTMKVCALRVNAACPIANRTIGEIRLLHN
EEEECCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEECCCCCCCCCCHHHEEEECC
EFPFRVVAIARGINTIIPGDDDTIMPNDQVFIMVNGAYLSRLMQLLGMKEQTIQRVMIVG
CCCEEEEEECCCCCEECCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHEEEEEC
GGMVGARVAELLCKTVRINLIESDQQHAEELALSLKNTDVLHGDGTDVNVMVLGGLMEMD
CCHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCEEEECCCCCEEEEEECCEEEEE
IFIATTGNNETNIISCLLAKHMMNRTNVDPAGKEGKTIALVKKEDYLVLASTIGLDIALN
EEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEEECCEEEEEE
MKISAANEIMKFIRIGELLSVAHLHGVDAEVIELVAADRSPITKKRLGKLRSTLQDKGIL
EEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCEE
VAGIITNGTCILTDDDTLIEPNERAIVVSATRSLKDAQQLFQ
EEEEEECCEEEEECCCCEECCCCCEEEEEEHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]