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The map label for this gene is serB [H]

Identifier: 193213509

GI number: 193213509

Start: 2058029

End: 2059252

Strand: Direct

Name: serB [H]

Synonym: Cpar_1870

Alternate gene names: 193213509

Gene position: 2058029-2059252 (Clockwise)

Preceding gene: 193213507

Following gene: 193213513

Centisome position: 89.9

GC content: 60.05

Gene sequence:

>1224_bases
ATGCGCGAACTGCTGCTCATTACCATTTCCGGCCCGGACAAGCCAGGCCTGACCTCCAAAATCACCGAAGTCCTGGCACG
CTACGACGTACCGGTGCTCGATATTGGCCAGTCGGTCATTCACAACCACCTCTCGCTCGGAATGCTCATCGAGGTGCCGA
AAGCCTCCACCTCCGCGCCGATCCTGAAAGACCTGCTCTTTACGGCGCACACGCTCGGCCTTGTGATAGAATTTTCGCCG
ATCAACACGCGCGAATACCACAAATGGGTCGGCGAACAAGGCAAGCCGCGCTATCTGCTTTCGCTGCTCGGGCGGAAAAT
TTCATCGGAACATCTCGAACGGGTCACCACGCTGGTCTCGAAGCACGGCCTCAACATCGACACCATCAACCGCCTCTCCG
GACGCCTGCCGCTCGAAGACGAGCGCGATCCGGGCCAGACCAAGGCGTGCATCGAGTTTTCGCTGAGGGGCGCGCTCAAC
GACGAAGAGCAGCTCAGGGCAGAAATGCTCGACATCACCGACAGCCTCGGAGTGGACATCGCGTTCCAGGAGGACAACAT
CTTCCGGCGCACCCGCCGCCTCGTGGTGTTCGACATGGACTCGACGCTGATTACGTCGGAGGTGATCGATGAGCTGGCGA
AAGAGGCCGGGTCGGGCGATCAGGTGGCGGCCATCACCGAGCAGGCGATGCGCGGGGAACTCGACTTCACCGAAAGCCTG
AAAATGCGGGTCGGCACGCTAAAAGGGCTGGAAGAATCGACGCTGCAAAAGGTGGCCGAGCGGCTGCAACTGACCGAAGG
CGCAGAGCACTTGTTCCACAACCTGCACCGCCTCGGCTTCAAAACCGCCATTCTCTCCGGTGGGTTCACCTACTTCGGGC
GCTACTTGCAGAAAAAGCTGAACATCGACTACGTCTTCGCCAACGAGCTGGAGATTGTGGACGGCAAGATGACTGGCAAC
GTCATTGGCCAGGTGGTCGATGGCAAACGCAAGGCGGCACTGCTGGAAGAGATCGCCACCACGGAAAACATCCGCCTCGA
ACAGACCGTCGCGGTCGGCGACGGAGCAAACGACCTCCCCATGCTCGGCAAAGCCGGACTCGGCATCGCATTCCGCGCCA
AGCCAATCGTGCGCGAAACCGCAAAGCAGGCAATCTCTACGCTCGGCCTCGACGCGATACTTTATTTGATGGGATTCCGC
GACCGCGACGCGCTGGAGGTGTAA

Upstream 100 bases:

>100_bases
CCGTGCTTCACCCGCAAACCGGGCAGAATCATAAGCCATTACAAGACAACGCCTTGCCGCTCTCCCTCCGTCGTGGAGGA
ATAACCGACACCTTCAGCAC

Downstream 100 bases:

>100_bases
GAAGCCGAATCAGGGAAAAGAAAAAATGGACGCTTATGACGTCCATTTTTTTCGTTAATCCACGTATTCCACAAAACGCT
CGAACTCCCGAGGATCGGGC

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRELLLITISGPDKPGLTSKITEVLARYDVPVLDIGQSVIHNHLSLGMLIEVPKASTSAPILKDLLFTAHTLGLVIEFSP
INTREYHKWVGEQGKPRYLLSLLGRKISSEHLERVTTLVSKHGLNIDTINRLSGRLPLEDERDPGQTKACIEFSLRGALN
DEEQLRAEMLDITDSLGVDIAFQEDNIFRRTRRLVVFDMDSTLITSEVIDELAKEAGSGDQVAAITEQAMRGELDFTESL
KMRVGTLKGLEESTLQKVAERLQLTEGAEHLFHNLHRLGFKTAILSGGFTYFGRYLQKKLNIDYVFANELEIVDGKMTGN
VIGQVVDGKRKAALLEEIATTENIRLEQTVAVGDGANDLPMLGKAGLGIAFRAKPIVRETAKQAISTLGLDAILYLMGFR
DRDALEV

Sequences:

>Translated_407_residues
MRELLLITISGPDKPGLTSKITEVLARYDVPVLDIGQSVIHNHLSLGMLIEVPKASTSAPILKDLLFTAHTLGLVIEFSP
INTREYHKWVGEQGKPRYLLSLLGRKISSEHLERVTTLVSKHGLNIDTINRLSGRLPLEDERDPGQTKACIEFSLRGALN
DEEQLRAEMLDITDSLGVDIAFQEDNIFRRTRRLVVFDMDSTLITSEVIDELAKEAGSGDQVAAITEQAMRGELDFTESL
KMRVGTLKGLEESTLQKVAERLQLTEGAEHLFHNLHRLGFKTAILSGGFTYFGRYLQKKLNIDYVFANELEIVDGKMTGN
VIGQVVDGKRKAALLEEIATTENIRLEQTVAVGDGANDLPMLGKAGLGIAFRAKPIVRETAKQAISTLGLDAILYLMGFR
DRDALEV
>Mature_407_residues
MRELLLITISGPDKPGLTSKITEVLARYDVPVLDIGQSVIHNHLSLGMLIEVPKASTSAPILKDLLFTAHTLGLVIEFSP
INTREYHKWVGEQGKPRYLLSLLGRKISSEHLERVTTLVSKHGLNIDTINRLSGRLPLEDERDPGQTKACIEFSLRGALN
DEEQLRAEMLDITDSLGVDIAFQEDNIFRRTRRLVVFDMDSTLITSEVIDELAKEAGSGDQVAAITEQAMRGELDFTESL
KMRVGTLKGLEESTLQKVAERLQLTEGAEHLFHNLHRLGFKTAILSGGFTYFGRYLQKKLNIDYVFANELEIVDGKMTGN
VIGQVVDGKRKAALLEEIATTENIRLEQTVAVGDGANDLPMLGKAGLGIAFRAKPIVRETAKQAISTLGLDAILYLMGFR
DRDALEV

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=202, Percent_Identity=32.6732673267327, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1790849, Length=196, Percent_Identity=58.1632653061224, Blast_Score=215, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI115534454, Length=222, Percent_Identity=31.5315315315315, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534456, Length=222, Percent_Identity=31.5315315315315, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=243, Percent_Identity=41.9753086419753, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24661601, Length=199, Percent_Identity=30.1507537688442, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 45048; Mature: 45048

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELLLITISGPDKPGLTSKITEVLARYDVPVLDIGQSVIHNHLSLGMLIEVPKASTSAP
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCHHHHHHHHCCCEEEEECCCCCCCH
ILKDLLFTAHTLGLVIEFSPINTREYHKWVGEQGKPRYLLSLLGRKISSEHLERVTTLVS
HHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KHGLNIDTINRLSGRLPLEDERDPGQTKACIEFSLRGALNDEEQLRAEMLDITDSLGVDI
HCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCEE
AFQEDNIFRRTRRLVVFDMDSTLITSEVIDELAKEAGSGDQVAAITEQAMRGELDFTESL
EECCCHHHHHHCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
KMRVGTLKGLEESTLQKVAERLQLTEGAEHLFHNLHRLGFKTAILSGGFTYFGRYLQKKL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
NIDYVFANELEIVDGKMTGNVIGQVVDGKRKAALLEEIATTENIRLEQTVAVGDGANDLP
CEEEEEECCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
MLGKAGLGIAFRAKPIVRETAKQAISTLGLDAILYLMGFRDRDALEV
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRELLLITISGPDKPGLTSKITEVLARYDVPVLDIGQSVIHNHLSLGMLIEVPKASTSAP
CCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHCHHHHHHHHCCCEEEEECCCCCCCH
ILKDLLFTAHTLGLVIEFSPINTREYHKWVGEQGKPRYLLSLLGRKISSEHLERVTTLVS
HHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KHGLNIDTINRLSGRLPLEDERDPGQTKACIEFSLRGALNDEEQLRAEMLDITDSLGVDI
HCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCEE
AFQEDNIFRRTRRLVVFDMDSTLITSEVIDELAKEAGSGDQVAAITEQAMRGELDFTESL
EECCCHHHHHHCEEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHH
KMRVGTLKGLEESTLQKVAERLQLTEGAEHLFHNLHRLGFKTAILSGGFTYFGRYLQKKL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHC
NIDYVFANELEIVDGKMTGNVIGQVVDGKRKAALLEEIATTENIRLEQTVAVGDGANDLP
CEEEEEECCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
MLGKAGLGIAFRAKPIVRETAKQAISTLGLDAILYLMGFRDRDALEV
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA