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The map label for this gene is aroE [H]

Identifier: 193213291

GI number: 193213291

Start: 1803407

End: 1804297

Strand: Direct

Name: aroE [H]

Synonym: Cpar_1649

Alternate gene names: 193213291

Gene position: 1803407-1804297 (Clockwise)

Preceding gene: 193213290

Following gene: 193213292

Centisome position: 78.78

GC content: 60.27

Gene sequence:

>891_bases
GTGTCAAAACGGCAGGCAATAAAGGTTTTCGGACTCATCGGCAGGAATGTCGATTACTCGTGGTCGCCGCTGATTCACAA
CACGGCGTTTCAGGCCCTCGGACTTCCCAGCATCTATACCATCTTCAATATCGCCGCTCCGGAACTGGTGGGCAACGCCC
TCACCGGAGCTCGCGCGCTCGGCATCGCCGGGTTCAACGTCACCATTCCGTACAAGAAAACCGTCGTCCCATTCCTTGAC
GAGCTGTCACCGGAAGCGCAGGCCATCGGCGCGGTGAACACCATCGTTAACGACAATGGCCGCCTGACTGGGCACAATAC
CGACATCGCCGGATTCGCCGCGCCGCTGCTGCCGATGGCGGAGCAAATTCACGGCAAGCCGGTCTGCATCTTCGGAAATG
GCGGAGCTGCCCTCGCCGCTGTCGAGGCGTTTCGACTCCACTTCCACCCTTCGTCGGTACGGCTCATGGTTCGGAATCTC
GAAAAAGCCGAAGCGATGCTCGAAGGGTACGCACACCGCGAGCTGGTCGAGCCCTGCCTGACCGCAGAGCTTGACACGCC
GGATGGCGAACGGCTACTCGGCGAGTGCTGCGTCATCGTCAACGCAACGCCCATCGGCACAGCCGGGCGGAGTGACGCCA
TCCAAAGCGTCGTACCAGCGAGACGCAAGCTGCTGCACGAAGGCCAGATCGTCTATGATATGGTGTACAATCCGCTCGAA
ACGCCACTGCTCGCCGAAGCACGCGCAGCTGGCGCCGAGACCATTTCGGGCATCGAGATGCTCATCGGCCAGGCAGCCCG
CTCCTTCTCGATCTGGACTGGTCAGGAGATGCCCGTCGACACCGTCAGAAAAACCGTGCTCGACGAAATCGAAATCAGCG
TAAATGTCTGA

Upstream 100 bases:

>100_bases
CAAGAAGCAGCTCTTCCAGAGCACCTTCCCTGAACTTTATCAGCAGGATGCGGTGCGCAGGCTGCTCGACATTTCCTGAA
CCGAAGGTTCAACGCTCCTC

Downstream 100 bases:

>100_bases
TCCAGTGGTTTGAAAATCAGCCCTGGTGATGATATTTTACGTTTTGAATGCACGATACACCCGTCCCCAACATTAACACT
CTTTTCAATGGTACAATTTT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSKRQAIKVFGLIGRNVDYSWSPLIHNTAFQALGLPSIYTIFNIAAPELVGNALTGARALGIAGFNVTIPYKKTVVPFLD
ELSPEAQAIGAVNTIVNDNGRLTGHNTDIAGFAAPLLPMAEQIHGKPVCIFGNGGAALAAVEAFRLHFHPSSVRLMVRNL
EKAEAMLEGYAHRELVEPCLTAELDTPDGERLLGECCVIVNATPIGTAGRSDAIQSVVPARRKLLHEGQIVYDMVYNPLE
TPLLAEARAAGAETISGIEMLIGQAARSFSIWTGQEMPVDTVRKTVLDEIEISVNV

Sequences:

>Translated_296_residues
MSKRQAIKVFGLIGRNVDYSWSPLIHNTAFQALGLPSIYTIFNIAAPELVGNALTGARALGIAGFNVTIPYKKTVVPFLD
ELSPEAQAIGAVNTIVNDNGRLTGHNTDIAGFAAPLLPMAEQIHGKPVCIFGNGGAALAAVEAFRLHFHPSSVRLMVRNL
EKAEAMLEGYAHRELVEPCLTAELDTPDGERLLGECCVIVNATPIGTAGRSDAIQSVVPARRKLLHEGQIVYDMVYNPLE
TPLLAEARAAGAETISGIEMLIGQAARSFSIWTGQEMPVDTVRKTVLDEIEISVNV
>Mature_295_residues
SKRQAIKVFGLIGRNVDYSWSPLIHNTAFQALGLPSIYTIFNIAAPELVGNALTGARALGIAGFNVTIPYKKTVVPFLDE
LSPEAQAIGAVNTIVNDNGRLTGHNTDIAGFAAPLLPMAEQIHGKPVCIFGNGGAALAAVEAFRLHFHPSSVRLMVRNLE
KAEAMLEGYAHRELVEPCLTAELDTPDGERLLGECCVIVNATPIGTAGRSDAIQSVVPARRKLLHEGQIVYDMVYNPLET
PLLAEARAAGAETISGIEMLIGQAARSFSIWTGQEMPVDTVRKTVLDEIEISVNV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=288, Percent_Identity=32.6388888888889, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789675, Length=288, Percent_Identity=30.2083333333333, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=290, Percent_Identity=25.8620689655172, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893 [H]

Pfam domain/function: PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31736; Mature: 31605

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRQAIKVFGLIGRNVDYSWSPLIHNTAFQALGLPSIYTIFNIAAPELVGNALTGARAL
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHH
GIAGFNVTIPYKKTVVPFLDELSPEAQAIGAVNTIVNDNGRLTGHNTDIAGFAAPLLPMA
EEECCEEECCCHHHHHHHHHHCCCHHHHHHHHHEEECCCCEEECCCCCHHHHHHHHHHHH
EQIHGKPVCIFGNGGAALAAVEAFRLHFHPSSVRLMVRNLEKAEAMLEGYAHRELVEPCL
HHHCCCEEEEEECCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAELDTPDGERLLGECCVIVNATPIGTAGRSDAIQSVVPARRKLLHEGQIVYDMVYNPLE
HCCCCCCCHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHCCCC
TPLLAEARAAGAETISGIEMLIGQAARSFSIWTGQEMPVDTVRKTVLDEIEISVNV
CCHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHEEEEEC
>Mature Secondary Structure 
SKRQAIKVFGLIGRNVDYSWSPLIHNTAFQALGLPSIYTIFNIAAPELVGNALTGARAL
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHH
GIAGFNVTIPYKKTVVPFLDELSPEAQAIGAVNTIVNDNGRLTGHNTDIAGFAAPLLPMA
EEECCEEECCCHHHHHHHHHHCCCHHHHHHHHHEEECCCCEEECCCCCHHHHHHHHHHHH
EQIHGKPVCIFGNGGAALAAVEAFRLHFHPSSVRLMVRNLEKAEAMLEGYAHRELVEPCL
HHHCCCEEEEEECCCHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAELDTPDGERLLGECCVIVNATPIGTAGRSDAIQSVVPARRKLLHEGQIVYDMVYNPLE
HCCCCCCCHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHCCCC
TPLLAEARAAGAETISGIEMLIGQAARSFSIWTGQEMPVDTVRKTVLDEIEISVNV
CCHHHHHHHCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]