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The map label for this gene is lspA

Identifier: 193213292

GI number: 193213292

Start: 1804385

End: 1804867

Strand: Direct

Name: lspA

Synonym: Cpar_1650

Alternate gene names: 193213292

Gene position: 1804385-1804867 (Clockwise)

Preceding gene: 193213291

Following gene: 193213293

Centisome position: 78.82

GC content: 49.48

Gene sequence:

>483_bases
ATGGTACAATTTTACCTCCTGACGTTGGTATTCATCGTCGTCGATCGCTTCGCAAAACTATTTGCGATCAACGTACTAAG
AGACCTCCCCAACGGGATCGTGCTCGTACCGGACTGGTTCAAACTTATGTACGCCGAAAACCTTGGCATTGCTTTCGGGT
TGCGATTACTACCGCCCGAAGGCATTCTGCTGTTAGCCCTCGCTATCTCCGCTGGGCTAACTTGGTATGTCTGGATATCG
CAAAACCGCAGCCCGTTGTTCATCTTAACCTTCGCGCTCATCCTGGGCGGAGGTCTCGGCAACCTCATTGACCGCTTAAT
ATTCGGCCATGTTGTTGACTTCATCTATTTCGATATTTACCAAGGAACACTTTTCGGCAAATACGTATCGCTCTGGCCGA
TCTTCAACATCGCCGATGCGTGCATCACCATCGGCGCGTGCCTGCTGTTTTTCTTTCACGATAAGATTTTCAACCCGCGA
TAA

Upstream 100 bases:

>100_bases
CGTAAATGTCTGATCCAGTGGTTTGAAAATCAGCCCTGGTGATGATATTTTACGTTTTGAATGCACGATACACCCGTCCC
CAACATTAACACTCTTTTCA

Downstream 100 bases:

>100_bases
CCATGACGTCGTCCTCCCTGGCCGACATCCACTGCCACCTCTCGTTCCCGGAGTTCGACGAAGACCGCGAGCAGGTGATC
GAGCGGCTCCGGGAGGCGGG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MVQFYLLTLVFIVVDRFAKLFAINVLRDLPNGIVLVPDWFKLMYAENLGIAFGLRLLPPEGILLLALAISAGLTWYVWIS
QNRSPLFILTFALILGGGLGNLIDRLIFGHVVDFIYFDIYQGTLFGKYVSLWPIFNIADACITIGACLLFFFHDKIFNPR

Sequences:

>Translated_160_residues
MVQFYLLTLVFIVVDRFAKLFAINVLRDLPNGIVLVPDWFKLMYAENLGIAFGLRLLPPEGILLLALAISAGLTWYVWIS
QNRSPLFILTFALILGGGLGNLIDRLIFGHVVDFIYFDIYQGTLFGKYVSLWPIFNIADACITIGACLLFFFHDKIFNPR
>Mature_160_residues
MVQFYLLTLVFIVVDRFAKLFAINVLRDLPNGIVLVPDWFKLMYAENLGIAFGLRLLPPEGILLLALAISAGLTWYVWIS
QNRSPLFILTFALILGGGLGNLIDRLIFGHVVDFIYFDIYQGTLFGKYVSLWPIFNIADACITIGACLLFFFHDKIFNPR

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LSPA_CHLP8 (B3QQ42)

Other databases:

- EMBL:   CP001099
- RefSeq:   YP_001999245.1
- MEROPS:   A08.001
- GeneID:   6420591
- GenomeReviews:   CP001099_GR
- KEGG:   cpc:Cpar_1650
- HOGENOM:   HBG724422
- OMA:   ADACITI
- ProtClustDB:   PRK14787
- GO:   GO:0006508
- HAMAP:   MF_00161
- InterPro:   IPR001872
- PRINTS:   PR00781
- TIGRFAMs:   TIGR00077

Pfam domain/function: PF01252 Peptidase_A8

EC number: =3.4.23.36

Molecular weight: Translated: 18152; Mature: 18152

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00855 SPASE_II

Important sites: ACT_SITE 104-104 ACT_SITE 139-139

Signals:

None

Transmembrane regions:

HASH(0x1d7556e8)-; HASH(0x1d3450e8)-; HASH(0x1df9d1e4)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQFYLLTLVFIVVDRFAKLFAINVLRDLPNGIVLVPDWFKLMYAENLGIAFGLRLLPPE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCEEEEEECCCC
GILLLALAISAGLTWYVWISQNRSPLFILTFALILGGGLGNLIDRLIFGHVVDFIYFDIY
CHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QGTLFGKYVSLWPIFNIADACITIGACLLFFFHDKIFNPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MVQFYLLTLVFIVVDRFAKLFAINVLRDLPNGIVLVPDWFKLMYAENLGIAFGLRLLPPE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCEEEEEECCCC
GILLLALAISAGLTWYVWISQNRSPLFILTFALILGGGLGNLIDRLIFGHVVDFIYFDIY
CHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QGTLFGKYVSLWPIFNIADACITIGACLLFFFHDKIFNPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA