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The map label for this gene is 193213290

Identifier: 193213290

GI number: 193213290

Start: 1801988

End: 1803385

Strand: Direct

Name: 193213290

Synonym: Cpar_1648

Alternate gene names: NA

Gene position: 1801988-1803385 (Clockwise)

Preceding gene: 193213289

Following gene: 193213291

Centisome position: 78.72

GC content: 57.01

Gene sequence:

>1398_bases
ATGAGTCTGCTTGATTTTTTTGATGATGACCAGAACTATTCGGCGGAAGATTTTCCATACCGTCCGGAAGGGGATTCCGA
CCCCGATTTAATCCACGATCCCGAAGAACTGATCGACCTGATCGCCCGCCTCAACGAAGAGGGCGTGTACGATCAGTCGC
TTGTTGCAGCCCGCCGACTTGAAGAACTCGCCCCATACAATGCGGAAACCTGGTTTCACCTGGGCAACAGCCTGACGCTC
AACAGCCTGTTTGACGAAGCGCTCGAAGCGTTCCAGCACGCCATGGTGCTCAGCCCCGCAGATAGCGAAATGACCCTCAA
CCTCGCGCTGGCGTACTTCAATACCGGAAAGCTCGAAGAGGCGCTCGATGAAATCGACAGGGTCGTGACCGATTCGACCA
CCGAAAAGGAGACGCACTTCTATCGTGGGCTCATTCTCCAGCGACTCGAACGGTTCGATGAGGCCGAAGGCCATTTCAGC
CACAGCCTCAGCTTCGACCCGGAGTTCGCCGAGGCCTGGTACGAGCTGGCTTATTCGCGCGATATCCTCGGCAAGCTGGA
CGAAGCCCTCGTCGCTTACGACAAAGCCATCGATCTCGATCCGTACAACATCAACGCCTGGTACAACAAGGGCCTTGTAC
TGAGCAAGCTCAAACGCTACAGCGAAGCGCTTGAGGCTTACGACATGGCGCTGGCCATTTCGGACGATTTCAGCTCGGCA
TGGTACAACCGCGCCAATGTGCTGGCCATCACAGGCAGAATCGAAGAGGCTGCCGAAAGCTATTCGAAAACCCTTGAGAT
CGAACCGGACGAAATCAACGCGCTCTACAATCTCGGCATCGCAAGGGAAGAGCTCGAAGAGTACGAACAGGCCATCGCCT
GCTACAACCGCTGCATCGAGCTGAACCCCGAGTTCGCCGACGCCTGGTTCGCGCTCGCCTGCTGCTACGAAGCTCAGGAA
AAGTACGAAGCGTCCCTGGAGTCCATCGGCCATGCACTTTCGGAAATACCGGAAAGCCTCGACTTCCTTCTGCTCAAGGC
GGAGATCGAATACAACCTCGGTCGGCTCGACCAGTCACGCCGCACCTACGAAACCATCATCCCGCTGGAGCCGGAAAGCC
CACAGATCTGGCTCGACTATGCGATGGTGCTGCGCGAGGCCGGTGCAATGGACGACTCCATCCGCGCCCTCGAAGAGTCC
ATCTCGCTGCAACCGTTCTCGGCGGAAGCGCACTTCGAGATCGCCGCAACCTACTTCGCGATGGGCGACAATCAGAGCAC
GGTCAAGGCGCTCAGCAAAGCCTTCAAGATCGATCCTGACAAGAAGCAGCTCTTCCAGAGCACCTTCCCTGAACTTTATC
AGCAGGATGCGGTGCGCAGGCTGCTCGACATTTCCTGA

Upstream 100 bases:

>100_bases
CCATAAACGCACCTTCCGGAAAGGGCTCTTTTTTTGAAAAAAAATCTGCTATATTTTCTCGTGTGATTTTTTATGATCGT
GAAAGCTTGAAAAAGCGTGT

Downstream 100 bases:

>100_bases
ACCGAAGGTTCAACGCTCCTCGTGTCAAAACGGCAGGCAATAAAGGTTTTCGGACTCATCGGCAGGAATGTCGATTACTC
GTGGTCGCCGCTGATTCACA

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSLLDFFDDDQNYSAEDFPYRPEGDSDPDLIHDPEELIDLIARLNEEGVYDQSLVAARRLEELAPYNAETWFHLGNSLTL
NSLFDEALEAFQHAMVLSPADSEMTLNLALAYFNTGKLEEALDEIDRVVTDSTTEKETHFYRGLILQRLERFDEAEGHFS
HSLSFDPEFAEAWYELAYSRDILGKLDEALVAYDKAIDLDPYNINAWYNKGLVLSKLKRYSEALEAYDMALAISDDFSSA
WYNRANVLAITGRIEEAAESYSKTLEIEPDEINALYNLGIAREELEEYEQAIACYNRCIELNPEFADAWFALACCYEAQE
KYEASLESIGHALSEIPESLDFLLLKAEIEYNLGRLDQSRRTYETIIPLEPESPQIWLDYAMVLREAGAMDDSIRALEES
ISLQPFSAEAHFEIAATYFAMGDNQSTVKALSKAFKIDPDKKQLFQSTFPELYQQDAVRRLLDIS

Sequences:

>Translated_465_residues
MSLLDFFDDDQNYSAEDFPYRPEGDSDPDLIHDPEELIDLIARLNEEGVYDQSLVAARRLEELAPYNAETWFHLGNSLTL
NSLFDEALEAFQHAMVLSPADSEMTLNLALAYFNTGKLEEALDEIDRVVTDSTTEKETHFYRGLILQRLERFDEAEGHFS
HSLSFDPEFAEAWYELAYSRDILGKLDEALVAYDKAIDLDPYNINAWYNKGLVLSKLKRYSEALEAYDMALAISDDFSSA
WYNRANVLAITGRIEEAAESYSKTLEIEPDEINALYNLGIAREELEEYEQAIACYNRCIELNPEFADAWFALACCYEAQE
KYEASLESIGHALSEIPESLDFLLLKAEIEYNLGRLDQSRRTYETIIPLEPESPQIWLDYAMVLREAGAMDDSIRALEES
ISLQPFSAEAHFEIAATYFAMGDNQSTVKALSKAFKIDPDKKQLFQSTFPELYQQDAVRRLLDIS
>Mature_464_residues
SLLDFFDDDQNYSAEDFPYRPEGDSDPDLIHDPEELIDLIARLNEEGVYDQSLVAARRLEELAPYNAETWFHLGNSLTLN
SLFDEALEAFQHAMVLSPADSEMTLNLALAYFNTGKLEEALDEIDRVVTDSTTEKETHFYRGLILQRLERFDEAEGHFSH
SLSFDPEFAEAWYELAYSRDILGKLDEALVAYDKAIDLDPYNINAWYNKGLVLSKLKRYSEALEAYDMALAISDDFSSAW
YNRANVLAITGRIEEAAESYSKTLEIEPDEINALYNLGIAREELEEYEQAIACYNRCIELNPEFADAWFALACCYEAQEK
YEASLESIGHALSEIPESLDFLLLKAEIEYNLGRLDQSRRTYETIIPLEPESPQIWLDYAMVLREAGAMDDSIRALEESI
SLQPFSAEAHFEIAATYFAMGDNQSTVKALSKAFKIDPDKKQLFQSTFPELYQQDAVRRLLDIS

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=392, Percent_Identity=26.530612244898, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI32307150, Length=392, Percent_Identity=26.530612244898, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI224809432, Length=361, Percent_Identity=24.9307479224377, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI83415184, Length=328, Percent_Identity=23.780487804878, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI301336134, Length=328, Percent_Identity=23.780487804878, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI310131789, Length=334, Percent_Identity=22.4550898203593, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI310110582, Length=334, Percent_Identity=22.4550898203593, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI310123097, Length=334, Percent_Identity=22.4550898203593, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI22749211, Length=239, Percent_Identity=29.2887029288703, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI118766330, Length=246, Percent_Identity=24.390243902439, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI118766328, Length=246, Percent_Identity=24.390243902439, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI25952122, Length=417, Percent_Identity=22.5419664268585, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI167466177, Length=300, Percent_Identity=23, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI167466175, Length=300, Percent_Identity=23, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=386, Percent_Identity=26.9430051813472, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI115532690, Length=372, Percent_Identity=24.1935483870968, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319387, Length=280, Percent_Identity=26.0714285714286, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI17647755, Length=392, Percent_Identity=25.5102040816327, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24585827, Length=392, Percent_Identity=25.5102040816327, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24585829, Length=392, Percent_Identity=25.5102040816327, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24647123, Length=257, Percent_Identity=24.124513618677, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076610, Length=296, Percent_Identity=23.6486486486486, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920486, Length=296, Percent_Identity=23.6486486486486, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24656717, Length=219, Percent_Identity=25.5707762557078, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18110006, Length=219, Percent_Identity=25.5707762557078, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 53122; Mature: 52991

Theoretical pI: Translated: 3.97; Mature: 3.97

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLDFFDDDQNYSAEDFPYRPEGDSDPDLIHDPEELIDLIARLNEEGVYDQSLVAARRL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
EELAPYNAETWFHLGNSLTLNSLFDEALEAFQHAMVLSPADSEMTLNLALAYFNTGKLEE
HHHCCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEECCCCHHH
ALDEIDRVVTDSTTEKETHFYRGLILQRLERFDEAEGHFSHSLSFDPEFAEAWYELAYSR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
DILGKLDEALVAYDKAIDLDPYNINAWYNKGLVLSKLKRYSEALEAYDMALAISDDFSSA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCHHHH
WYNRANVLAITGRIEEAAESYSKTLEIEPDEINALYNLGIAREELEEYEQAIACYNRCIE
HHCCCCEEEEECCHHHHHHHHHHEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
LNPEFADAWFALACCYEAQEKYEASLESIGHALSEIPESLDFLLLKAEIEYNLGRLDQSR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCHHHCCHHC
RTYETIIPLEPESPQIWLDYAMVLREAGAMDDSIRALEESISLQPFSAEAHFEIAATYFA
CHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
MGDNQSTVKALSKAFKIDPDKKQLFQSTFPELYQQDAVRRLLDIS
ECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLLDFFDDDQNYSAEDFPYRPEGDSDPDLIHDPEELIDLIARLNEEGVYDQSLVAARRL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
EELAPYNAETWFHLGNSLTLNSLFDEALEAFQHAMVLSPADSEMTLNLALAYFNTGKLEE
HHHCCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEEECCCCHHH
ALDEIDRVVTDSTTEKETHFYRGLILQRLERFDEAEGHFSHSLSFDPEFAEAWYELAYSR
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
DILGKLDEALVAYDKAIDLDPYNINAWYNKGLVLSKLKRYSEALEAYDMALAISDDFSSA
HHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCHHHH
WYNRANVLAITGRIEEAAESYSKTLEIEPDEINALYNLGIAREELEEYEQAIACYNRCIE
HHCCCCEEEEECCHHHHHHHHHHEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
LNPEFADAWFALACCYEAQEKYEASLESIGHALSEIPESLDFLLLKAEIEYNLGRLDQSR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHCHHHCCHHC
RTYETIIPLEPESPQIWLDYAMVLREAGAMDDSIRALEESISLQPFSAEAHFEIAATYFA
CHHHHEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEE
MGDNQSTVKALSKAFKIDPDKKQLFQSTFPELYQQDAVRRLLDIS
ECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]