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The map label for this gene is ykcC [H]

Identifier: 193213104

GI number: 193213104

Start: 1595525

End: 1596481

Strand: Direct

Name: ykcC [H]

Synonym: Cpar_1459

Alternate gene names: 193213104

Gene position: 1595525-1596481 (Clockwise)

Preceding gene: 193213103

Following gene: 193213105

Centisome position: 69.7

GC content: 48.07

Gene sequence:

>957_bases
ATGAATGAGAGCGGTAAAAAGATGATCAGCCTGGTCTCTCCTTGTTTCAATGAAGAGGAGAATGTCGAGGAACTCTACCG
GCAGCTCACTGCCGTCATGGCTGGCATGGAAGGGTACGACTACGAATTCATTCTGATCGACAATGCCTCGACGGATTCGA
CGGTGCAGAAAATCAAGAGGATCGCCGCGCAGGACAAGCGGGTGAAGTTGATTGTCAATTCGAGAAATTTCGGTCATATC
CGCTCTCCGTATCATGCGATACTTCAAAGCAGCGGAGATGCCTGTATCGTGATGGCGTCAGATCTCCAAGACCCGCCAGA
CATGATTCCGGAACTCATAAAGAAATGGGAAGAGGGTGCGCAAATCGTAGCGGCTGTCAAAAAAGAGAGCAAGGAAAGCA
AGTTGATGTTCGGCATTCGAAAGCTGTATTACGGTCTGCTCAAATCCGTATCGGATGTGAATATCATCCAGAACTATACC
GGTTTCGGCTTGTATGACCGAAAGATCATAGAGATTCTGAAGAACATTCCAGACCCTTATCCGTTTTTCAGAGGCATTAT
TGCTGAAGTCGGGTTCAGGGTTGAGCGGATTACCTATACCCAGCCGAGACGAGCGCGAGGTATTACCAAGAACAACTTTT
TTACCCTGTACGATATCGGGATTCTGGGTATCATCAGTAATTCCAAAGTCCCGTTACGACTTGCGACGTTTTCCGGCTTT
GTGCTTTCGTTTTTGAGCTTTCTGGTCGGGATCGGCTATCTTGTTGGCAAGCTCATCTTCTGGGACAATTTTCAGGCAGG
CATCGCGCCGCTACTTATCGGTAATTTCTTTTTCTTCGGCCTGATGCTGTTTTTTATCGGCATTCTTGGGGAATACGTGG
GGGCAATTTACACTCAGGTTCTTGCGAGACCGCGGGTGTACGAATCCGAGCGGATCAATTTTGACCAGACAGAGTGA

Upstream 100 bases:

>100_bases
TTCGATCTGGATCGCGCAGTTTCTTATTATTGCCGTTACAGCGCTGATTTCTTTTTTTGGACACCGAGGCTTTACCTTCA
AACGATAACCATGTTTTGTT

Downstream 100 bases:

>100_bases
GTTTATTTATGCGCGCCTCTCCTCGGCTTCCGATAATACTGCCGACCTATAACAGCAGCGTATTTCATGAAAAAAACTTG
CTGAACACGCTTTTCTGAAG

Product: family 2 glycosyl transferase

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNESGKKMISLVSPCFNEEENVEELYRQLTAVMAGMEGYDYEFILIDNASTDSTVQKIKRIAAQDKRVKLIVNSRNFGHI
RSPYHAILQSSGDACIVMASDLQDPPDMIPELIKKWEEGAQIVAAVKKESKESKLMFGIRKLYYGLLKSVSDVNIIQNYT
GFGLYDRKIIEILKNIPDPYPFFRGIIAEVGFRVERITYTQPRRARGITKNNFFTLYDIGILGIISNSKVPLRLATFSGF
VLSFLSFLVGIGYLVGKLIFWDNFQAGIAPLLIGNFFFFGLMLFFIGILGEYVGAIYTQVLARPRVYESERINFDQTE

Sequences:

>Translated_318_residues
MNESGKKMISLVSPCFNEEENVEELYRQLTAVMAGMEGYDYEFILIDNASTDSTVQKIKRIAAQDKRVKLIVNSRNFGHI
RSPYHAILQSSGDACIVMASDLQDPPDMIPELIKKWEEGAQIVAAVKKESKESKLMFGIRKLYYGLLKSVSDVNIIQNYT
GFGLYDRKIIEILKNIPDPYPFFRGIIAEVGFRVERITYTQPRRARGITKNNFFTLYDIGILGIISNSKVPLRLATFSGF
VLSFLSFLVGIGYLVGKLIFWDNFQAGIAPLLIGNFFFFGLMLFFIGILGEYVGAIYTQVLARPRVYESERINFDQTE
>Mature_318_residues
MNESGKKMISLVSPCFNEEENVEELYRQLTAVMAGMEGYDYEFILIDNASTDSTVQKIKRIAAQDKRVKLIVNSRNFGHI
RSPYHAILQSSGDACIVMASDLQDPPDMIPELIKKWEEGAQIVAAVKKESKESKLMFGIRKLYYGLLKSVSDVNIIQNYT
GFGLYDRKIIEILKNIPDPYPFFRGIIAEVGFRVERITYTQPRRARGITKNNFFTLYDIGILGIISNSKVPLRLATFSGF
VLSFLSFLVGIGYLVGKLIFWDNFQAGIAPLLIGNFFFFGLMLFFIGILGEYVGAIYTQVLARPRVYESERINFDQTE

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788692, Length=298, Percent_Identity=33.2214765100671, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788588, Length=314, Percent_Identity=26.4331210191083, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 36108; Mature: 36108

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESGKKMISLVSPCFNEEENVEELYRQLTAVMAGMEGYDYEFILIDNASTDSTVQKIKR
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
IAAQDKRVKLIVNSRNFGHIRSPYHAILQSSGDACIVMASDLQDPPDMIPELIKKWEEGA
HHHCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
QIVAAVKKESKESKLMFGIRKLYYGLLKSVSDVNIIQNYTGFGLYDRKIIEILKNIPDPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PFFRGIIAEVGFRVERITYTQPRRARGITKNNFFTLYDIGILGIISNSKVPLRLATFSGF
HHHHHHHHHHCCHHEEEECCCCHHHCCCCCCCCEEEEEHHEEEEECCCCCCEEEHHHHHH
VLSFLSFLVGIGYLVGKLIFWDNFQAGIAPLLIGNFFFFGLMLFFIGILGEYVGAIYTQV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARPRVYESERINFDQTE
HHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNESGKKMISLVSPCFNEEENVEELYRQLTAVMAGMEGYDYEFILIDNASTDSTVQKIKR
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHH
IAAQDKRVKLIVNSRNFGHIRSPYHAILQSSGDACIVMASDLQDPPDMIPELIKKWEEGA
HHHCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
QIVAAVKKESKESKLMFGIRKLYYGLLKSVSDVNIIQNYTGFGLYDRKIIEILKNIPDPY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PFFRGIIAEVGFRVERITYTQPRRARGITKNNFFTLYDIGILGIISNSKVPLRLATFSGF
HHHHHHHHHHCCHHEEEECCCCHHHCCCCCCCCEEEEEHHEEEEECCCCCCEEEHHHHHH
VLSFLSFLVGIGYLVGKLIFWDNFQAGIAPLLIGNFFFFGLMLFFIGILGEYVGAIYTQV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARPRVYESERINFDQTE
HHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]