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The map label for this gene is rfbF [H]

Identifier: 193213093

GI number: 193213093

Start: 1584462

End: 1585238

Strand: Direct

Name: rfbF [H]

Synonym: Cpar_1448

Alternate gene names: 193213093

Gene position: 1584462-1585238 (Clockwise)

Preceding gene: 193213087

Following gene: 193213094

Centisome position: 69.21

GC content: 49.16

Gene sequence:

>777_bases
ATGAAAGCTGTTATTCTTGCAGGTGGTCTCGGCACCCGCATCTCCGAAGAGACTCACCTGAAGCCAAAACCGATGATTGA
AATCGGTGGCAAGCCGATTCTATGGCACATCATGAAAATTTATTCGGCTTACGGCGTTCACGACTTCATCATCTGCTGCG
GTTACAAGGGTTACCTGATAAAAGAGTATTTCGCCAACTACTTTCTGCACATGTCGGACATCACGTTCGACATGGAGCAT
AACGAGATGCAGGTCCATCATCATAAAGCCGAGCCCTGGCGCGTCACCCTGATCGATACTGGCGAACACACAATGACAGG
TGGCCGTCTCAAGAGAGTGCAAGACTATGTGAAAGACGAGAAGGAGGTCTTTTTTACCTATGGAGATGGTGTTAGCAATA
TCAACATAGATAAATTGCTTGCTTTTCACCGTTCCAAGGGAGTAAAGGCTACTCTTACGGCAACCATGCCTGCTTCCGGT
CGCTTTGGCGTGCTCGACATCGATAAGAACCACAAGGTTCATACCTTTAAGGAAAAGCCCAGAACCGATGGAGCAATGAT
TAATGGCGGCTTTTTCGTTCTCTCGCCTGAGGTGATCGATTATATTGAAGGTGATCACACCTCATGGGAACGGGAACCTC
TGGAGCGTCTTGCTGGAGAAGGTGAGCTTGCCGCTTATGCCCATCATGGGTTCTGGCAGCCAATGGATACCCTGCGTGAC
AAGGTAATGCTCGAAGAACTCTGGAAAACGGGCGCCGCTCCATGGAAGCTCTGGTAA

Upstream 100 bases:

>100_bases
ATGCAATAGATCTGAAAACTCTAATTTAGCCATTCCAGCTACGGGCATATAAGCAGATTTACGATTTACAACGAAGTCTT
TAGGCGTAAAACAAACTATC

Downstream 100 bases:

>100_bases
AGTGGTAATGGCGGATGAGACGATGCTGAACAACTTATTTTGGGCCGGTAAAAAAGTTCTTGTAACCGGGCACAGCGGTT
TCAAGGGCTCCTGGCTTGTT

Product: glucose-1-phosphate cytidylyltransferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MKAVILAGGLGTRISEETHLKPKPMIEIGGKPILWHIMKIYSAYGVHDFIICCGYKGYLIKEYFANYFLHMSDITFDMEH
NEMQVHHHKAEPWRVTLIDTGEHTMTGGRLKRVQDYVKDEKEVFFTYGDGVSNINIDKLLAFHRSKGVKATLTATMPASG
RFGVLDIDKNHKVHTFKEKPRTDGAMINGGFFVLSPEVIDYIEGDHTSWEREPLERLAGEGELAAYAHHGFWQPMDTLRD
KVMLEELWKTGAAPWKLW

Sequences:

>Translated_258_residues
MKAVILAGGLGTRISEETHLKPKPMIEIGGKPILWHIMKIYSAYGVHDFIICCGYKGYLIKEYFANYFLHMSDITFDMEH
NEMQVHHHKAEPWRVTLIDTGEHTMTGGRLKRVQDYVKDEKEVFFTYGDGVSNINIDKLLAFHRSKGVKATLTATMPASG
RFGVLDIDKNHKVHTFKEKPRTDGAMINGGFFVLSPEVIDYIEGDHTSWEREPLERLAGEGELAAYAHHGFWQPMDTLRD
KVMLEELWKTGAAPWKLW
>Mature_258_residues
MKAVILAGGLGTRISEETHLKPKPMIEIGGKPILWHIMKIYSAYGVHDFIICCGYKGYLIKEYFANYFLHMSDITFDMEH
NEMQVHHHKAEPWRVTLIDTGEHTMTGGRLKRVQDYVKDEKEVFFTYGDGVSNINIDKLLAFHRSKGVKATLTATMPASG
RFGVLDIDKNHKVHTFKEKPRTDGAMINGGFFVLSPEVIDYIEGDHTSWEREPLERLAGEGELAAYAHHGFWQPMDTLRD
KVMLEELWKTGAAPWKLW

Specific function: Involved in the biosynthesis of the tyvelose, a 3,6- dideoxyhexose found in the O-antigen of the surface lipopolysaccharides. It catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate. This enzyme can utilize either CTP or UTP as the nucle

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=246, Percent_Identity=28.8617886178862, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI11761619, Length=246, Percent_Identity=28.8617886178862, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI133931050, Length=248, Percent_Identity=28.6290322580645, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320148, Length=253, Percent_Identity=32.0158102766798, Blast_Score=112, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21355443, Length=247, Percent_Identity=27.9352226720648, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24644084, Length=247, Percent_Identity=27.9352226720648, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 29537; Mature: 29537

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVILAGGLGTRISEETHLKPKPMIEIGGKPILWHIMKIYSAYGVHDFIICCGYKGYLI
CCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCHHH
KEYFANYFLHMSDITFDMEHNEMQVHHHKAEPWRVTLIDTGEHTMTGGRLKRVQDYVKDE
HHHHHHHEEEECCEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC
KEVFFTYGDGVSNINIDKLLAFHRSKGVKATLTATMPASGRFGVLDIDKNHKVHTFKEKP
EEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCEEEECCCC
RTDGAMINGGFFVLSPEVIDYIEGDHTSWEREPLERLAGEGELAAYAHHGFWQPMDTLRD
CCCCEEEECCEEEECHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
KVMLEELWKTGAAPWKLW
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKAVILAGGLGTRISEETHLKPKPMIEIGGKPILWHIMKIYSAYGVHDFIICCGYKGYLI
CCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCHHH
KEYFANYFLHMSDITFDMEHNEMQVHHHKAEPWRVTLIDTGEHTMTGGRLKRVQDYVKDE
HHHHHHHEEEECCEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCC
KEVFFTYGDGVSNINIDKLLAFHRSKGVKATLTATMPASGRFGVLDIDKNHKVHTFKEKP
EEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCCEEEECCCC
RTDGAMINGGFFVLSPEVIDYIEGDHTSWEREPLERLAGEGELAAYAHHGFWQPMDTLRD
CCCCEEEECCEEEECHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
KVMLEELWKTGAAPWKLW
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]