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The map label for this gene is rfbG [H]

Identifier: 193213094

GI number: 193213094

Start: 1585246

End: 1586328

Strand: Direct

Name: rfbG [H]

Synonym: Cpar_1449

Alternate gene names: 193213094

Gene position: 1585246-1586328 (Clockwise)

Preceding gene: 193213093

Following gene: 193213095

Centisome position: 69.25

GC content: 55.86

Gene sequence:

>1083_bases
ATGGCGGATGAGACGATGCTGAACAACTTATTTTGGGCCGGTAAAAAAGTTCTTGTAACCGGGCACAGCGGTTTCAAGGG
CTCCTGGCTTGTTATCTGGCTGAAGATGATGGGAGCCGAGGTCTCCGGCTACGCCCTCGCTCCGTTGACTTCAAACGACA
ACTTCGTACTCTCCGGCATCGGAGAGCATATCGCCTCTCAAATCGGTGATGTCAGGGATTTTGACACACTGTTTCGCGTT
TTTGAACGGCAGCAGCCGGAGATCGTTTTTCATCTCGCCGCCCAGCCGCTGGTCAGGTATTCATACGAAAATCCCAAAGA
GACCTATGACGTCAATGTTGGCGGCACGGTCAACGTTTTTGAATGCTGCCGCCGCTGCGATTCGGTTCGGGTGATCATCA
ACGTCACGACCGACAAGTGTTACGAAAACAGGGAGTGGGTCTGGGGTTACCGGGAAAACGACCGGCTTGGCGGATTCGAT
CCCTACAGTTCAAGCAAGGCGTGCAGCGAACTGGTGACTGAGGCTTTCCGGAACTCCTTTTTCAATCCTGCGGACGTTGC
CCGACATGGCAAAAGTCTGGCGTCGGCCAGAGCCGGCAACGTTTTCGGAGGCGGCGACTGGCAGGTTGACCGGATTCTCC
CAGACTGCATAAGGCATCTCGAAAGGGGTGAACCGATCGTGGTGAGAAATCCTCACGCTGTCCGCCCGTGGCAGCATGTG
CTCGAACCGCTTTCCGGCTACCTGCTGCTGGCCGAGAAGCTCTTCGAGAATCCTGGGGTTTACGAAGGGGCCTGGAATTT
CGGGCCGGAAGAGTCCAGCTTCCTGACGGTCGGTGCACTGGTCGATTCTGTCGTCAAGGTCTGGGGAAGCGGATCGCGGG
AAAACCGTTCAAATCCGGAGGCAGTTCACGAGGCCCATCTGCTCAGGCTCGACATCACCAAGGCCAAAGCGCTTCTCGGC
TGGAAGCCGATATGGAGCATCGATCGCGCGGTCAGCGAAACGGTGAACTGGTACCAGCAGTACCAAAGTGGCCGGATATT
AGAGATTTGCCAGGCGCAGATCGAGGCTTACATGAATAGTTGA

Upstream 100 bases:

>100_bases
CATGGGTTCTGGCAGCCAATGGATACCCTGCGTGACAAGGTAATGCTCGAAGAACTCTGGAAAACGGGCGCCGCTCCATG
GAAGCTCTGGTAAAGTGGTA

Downstream 100 bases:

>100_bases
CAAGCGGAGAAATGCGTATGAAGGTGGTGTTTCTCGGCACGAACGGATGGTATGACTCATCCACAGGCAAGACGATCTGT
ACTCTTGTCGAAACCAGCGC

Product: CDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MADETMLNNLFWAGKKVLVTGHSGFKGSWLVIWLKMMGAEVSGYALAPLTSNDNFVLSGIGEHIASQIGDVRDFDTLFRV
FERQQPEIVFHLAAQPLVRYSYENPKETYDVNVGGTVNVFECCRRCDSVRVIINVTTDKCYENREWVWGYRENDRLGGFD
PYSSSKACSELVTEAFRNSFFNPADVARHGKSLASARAGNVFGGGDWQVDRILPDCIRHLERGEPIVVRNPHAVRPWQHV
LEPLSGYLLLAEKLFENPGVYEGAWNFGPEESSFLTVGALVDSVVKVWGSGSRENRSNPEAVHEAHLLRLDITKAKALLG
WKPIWSIDRAVSETVNWYQQYQSGRILEICQAQIEAYMNS

Sequences:

>Translated_360_residues
MADETMLNNLFWAGKKVLVTGHSGFKGSWLVIWLKMMGAEVSGYALAPLTSNDNFVLSGIGEHIASQIGDVRDFDTLFRV
FERQQPEIVFHLAAQPLVRYSYENPKETYDVNVGGTVNVFECCRRCDSVRVIINVTTDKCYENREWVWGYRENDRLGGFD
PYSSSKACSELVTEAFRNSFFNPADVARHGKSLASARAGNVFGGGDWQVDRILPDCIRHLERGEPIVVRNPHAVRPWQHV
LEPLSGYLLLAEKLFENPGVYEGAWNFGPEESSFLTVGALVDSVVKVWGSGSRENRSNPEAVHEAHLLRLDITKAKALLG
WKPIWSIDRAVSETVNWYQQYQSGRILEICQAQIEAYMNS
>Mature_359_residues
ADETMLNNLFWAGKKVLVTGHSGFKGSWLVIWLKMMGAEVSGYALAPLTSNDNFVLSGIGEHIASQIGDVRDFDTLFRVF
ERQQPEIVFHLAAQPLVRYSYENPKETYDVNVGGTVNVFECCRRCDSVRVIINVTTDKCYENREWVWGYRENDRLGGFDP
YSSSKACSELVTEAFRNSFFNPADVARHGKSLASARAGNVFGGGDWQVDRILPDCIRHLERGEPIVVRNPHAVRPWQHVL
EPLSGYLLLAEKLFENPGVYEGAWNFGPEESSFLTVGALVDSVVKVWGSGSRENRSNPEAVHEAHLLRLDITKAKALLGW
KPIWSIDRAVSETVNWYQQYQSGRILEICQAQIEAYMNS

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI42516563, Length=339, Percent_Identity=27.4336283185841, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1788353, Length=355, Percent_Identity=23.943661971831, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI48994969, Length=356, Percent_Identity=23.876404494382, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532424, Length=344, Percent_Identity=22.3837209302326, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 40583; Mature: 40452

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADETMLNNLFWAGKKVLVTGHSGFKGSWLVIWLKMMGAEVSGYALAPLTSNDNFVLSGI
CCCHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEHH
GEHIASQIGDVRDFDTLFRVFERQQPEIVFHLAAQPLVRYSYENPKETYDVNVGGTVNVF
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEEECCCCCCCHH
ECCRRCDSVRVIINVTTDKCYENREWVWGYRENDRLGGFDPYSSSKACSELVTEAFRNSF
HHHHCCCCEEEEEEECCHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
FNPADVARHGKSLASARAGNVFGGGDWQVDRILPDCIRHLERGEPIVVRNPHAVRPWQHV
CCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
LEPLSGYLLLAEKLFENPGVYEGAWNFGPEESSFLTVGALVDSVVKVWGSGSRENRSNPE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCHH
AVHEAHLLRLDITKAKALLGWKPIWSIDRAVSETVNWYQQYQSGRILEICQAQIEAYMNS
HHHHHHHHEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADETMLNNLFWAGKKVLVTGHSGFKGSWLVIWLKMMGAEVSGYALAPLTSNDNFVLSGI
CCHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEHH
GEHIASQIGDVRDFDTLFRVFERQQPEIVFHLAAQPLVRYSYENPKETYDVNVGGTVNVF
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEEECCCCCCCHH
ECCRRCDSVRVIINVTTDKCYENREWVWGYRENDRLGGFDPYSSSKACSELVTEAFRNSF
HHHHCCCCEEEEEEECCHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
FNPADVARHGKSLASARAGNVFGGGDWQVDRILPDCIRHLERGEPIVVRNPHAVRPWQHV
CCHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
LEPLSGYLLLAEKLFENPGVYEGAWNFGPEESSFLTVGALVDSVVKVWGSGSRENRSNPE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCHH
AVHEAHLLRLDITKAKALLGWKPIWSIDRAVSETVNWYQQYQSGRILEICQAQIEAYMNS
HHHHHHHHEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]