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The map label for this gene is ahpC [C]

Identifier: 193213061

GI number: 193213061

Start: 1544777

End: 1545448

Strand: Direct

Name: ahpC [C]

Synonym: Cpar_1414

Alternate gene names: 193213061

Gene position: 1544777-1545448 (Clockwise)

Preceding gene: 193213052

Following gene: 193213062

Centisome position: 67.48

GC content: 56.99

Gene sequence:

>672_bases
ATGTCAAATTTTGACGACGAAATGTACTTTGAAATGTCCATGCCGCTGCTTGGCGACGACTTTCCGGAACTGAACGTCCA
GACCACGCATGGCCCGATGAGCATCCCCGGCGACCTGAAGGGATCATGGTTCGTGCTCTTCAGCCATCCGGCAGACTATA
CCCCTGTCTGCACCACCGAGTTCGTAGCGTTCCAGCAGCGCGCTGAAAAATTCGAAGAGATCGGCTGCAAGCTCATCGGC
ATGAGCGTCGATCAGGTCTTCTCGCACATCAAGTGGGTCGAGTGGATCAAGGATAACCTGAACGTCGAGATCACCTTCCC
GATCGTGGCGGCCAACGACCGCATCGCCAACAAGCTCGGCATGTTGCACCCCGGCAAGGGCACCAACACCGTCCGCGCCG
TGTTCGTCGGCGACCCCGAAGGCAAGGTGCGCCTCGTGCTCTACTATCCTCAGGAGATCGGCCGCAACATGGATGAAATC
CTGCGCGCGGTAACAGCGTTGCAGATTTCCGACAAAAACAAGGTCGCCATGCCTGCCGACTGGCCGAACAATGCCCTGCT
CAACGACCGGGTTATCATCCCGCCGGCTACCAACATCAAGGATGCCGAAAAGCGCAAAGAGCAGCACGACTGCTACGACT
GGTGGTTCTGCCACAAACAGCTCAACAAGTAA

Upstream 100 bases:

>100_bases
ATTAACCCCGTGAACAAACGGCACTGATCCGACCATTCACCTGGTGCCAACCATTGTCTTTCACCAAACACCAAAACAAT
CAAAAAGGAGAAAATCCATC

Downstream 100 bases:

>100_bases
AAGCTGGCCTCATCTATCCATCAAAAGGCTGCTCCGGACTCCAGAACCGGGGCAGCCTTTTGCTTTTTCATCCTCGCTGC
GCATCACCATCAAAACCTTC

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSNFDDEMYFEMSMPLLGDDFPELNVQTTHGPMSIPGDLKGSWFVLFSHPADYTPVCTTEFVAFQQRAEKFEEIGCKLIG
MSVDQVFSHIKWVEWIKDNLNVEITFPIVAANDRIANKLGMLHPGKGTNTVRAVFVGDPEGKVRLVLYYPQEIGRNMDEI
LRAVTALQISDKNKVAMPADWPNNALLNDRVIIPPATNIKDAEKRKEQHDCYDWWFCHKQLNK

Sequences:

>Translated_223_residues
MSNFDDEMYFEMSMPLLGDDFPELNVQTTHGPMSIPGDLKGSWFVLFSHPADYTPVCTTEFVAFQQRAEKFEEIGCKLIG
MSVDQVFSHIKWVEWIKDNLNVEITFPIVAANDRIANKLGMLHPGKGTNTVRAVFVGDPEGKVRLVLYYPQEIGRNMDEI
LRAVTALQISDKNKVAMPADWPNNALLNDRVIIPPATNIKDAEKRKEQHDCYDWWFCHKQLNK
>Mature_222_residues
SNFDDEMYFEMSMPLLGDDFPELNVQTTHGPMSIPGDLKGSWFVLFSHPADYTPVCTTEFVAFQQRAEKFEEIGCKLIGM
SVDQVFSHIKWVEWIKDNLNVEITFPIVAANDRIANKLGMLHPGKGTNTVRAVFVGDPEGKVRLVLYYPQEIGRNMDEIL
RAVTALQISDKNKVAMPADWPNNALLNDRVIIPPATNIKDAEKRKEQHDCYDWWFCHKQLNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=199, Percent_Identity=38.1909547738693, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI4505591, Length=146, Percent_Identity=38.3561643835616, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32455266, Length=146, Percent_Identity=38.3561643835616, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32455264, Length=146, Percent_Identity=38.3561643835616, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32189392, Length=146, Percent_Identity=35.6164383561644, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI5802974, Length=149, Percent_Identity=32.8859060402685, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI32483377, Length=149, Percent_Identity=32.8859060402685, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI5453549, Length=170, Percent_Identity=32.3529411764706, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI33188454, Length=58, Percent_Identity=50, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1786822, Length=151, Percent_Identity=27.8145695364238, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554494, Length=146, Percent_Identity=39.041095890411, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25153706, Length=192, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI193204376, Length=179, Percent_Identity=33.5195530726257, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI32565831, Length=175, Percent_Identity=33.1428571428571, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319407, Length=203, Percent_Identity=39.9014778325123, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6323613, Length=148, Percent_Identity=34.4594594594595, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320661, Length=148, Percent_Identity=33.1081081081081, Blast_Score=82, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24581278, Length=195, Percent_Identity=37.9487179487179, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI17975518, Length=198, Percent_Identity=38.8888888888889, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24652434, Length=198, Percent_Identity=38.8888888888889, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24652436, Length=198, Percent_Identity=38.8888888888889, Blast_Score=127, Evalue=7e-30,
Organism=Drosophila melanogaster, GI21357347, Length=146, Percent_Identity=36.3013698630137, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI17738015, Length=172, Percent_Identity=32.5581395348837, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17157991, Length=146, Percent_Identity=33.5616438356164, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641739, Length=146, Percent_Identity=33.5616438356164, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24656348, Length=147, Percent_Identity=30.6122448979592, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17864676, Length=147, Percent_Identity=30.6122448979592, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 25519; Mature: 25388

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFDDEMYFEMSMPLLGDDFPELNVQTTHGPMSIPGDLKGSWFVLFSHPADYTPVCTTE
CCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHH
FVAFQQRAEKFEEIGCKLIGMSVDQVFSHIKWVEWIKDNLNVEITFPIVAANDRIANKLG
HHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHC
MLHPGKGTNTVRAVFVGDPEGKVRLVLYYPQEIGRNMDEILRAVTALQISDKNKVAMPAD
CCCCCCCCCEEEEEEEECCCCCEEEEEECCHHHCCCHHHHHHHHHHEEECCCCCEEECCC
WPNNALLNDRVIIPPATNIKDAEKRKEQHDCYDWWFCHKQLNK
CCCCCEECCEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNFDDEMYFEMSMPLLGDDFPELNVQTTHGPMSIPGDLKGSWFVLFSHPADYTPVCTTE
CCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCHHHH
FVAFQQRAEKFEEIGCKLIGMSVDQVFSHIKWVEWIKDNLNVEITFPIVAANDRIANKLG
HHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHC
MLHPGKGTNTVRAVFVGDPEGKVRLVLYYPQEIGRNMDEILRAVTALQISDKNKVAMPAD
CCCCCCCCCEEEEEEEECCCCCEEEEEECCHHHCCCHHHHHHHHHHEEECCCCCEEECCC
WPNNALLNDRVIIPPATNIKDAEKRKEQHDCYDWWFCHKQLNK
CCCCCEECCEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]