Click here to switch to the map view.

The map label for this gene is trpB-1 [H]

Identifier: 193213022

GI number: 193213022

Start: 1491346

End: 1492548

Strand: Direct

Name: trpB-1 [H]

Synonym: Cpar_1373

Alternate gene names: 193213022

Gene position: 1491346-1492548 (Clockwise)

Preceding gene: 193213020

Following gene: 193213024

Centisome position: 65.15

GC content: 60.52

Gene sequence:

>1203_bases
ATGACGCAGAAGGTCACCTACAACGCACCCGACGAATTCGGCCATTTCGGCACGTTCGGGGGCAAATTCATTCCCGAAAC
GCTGGTCAAAAACGCCGCCGATCTCGAAGAGGAGTACCTCAAGGCGAAAGATGATCCGGAGTTCCGCCAGACATTCGACA
ACCTGCTTCGCCATTACGTTGGCCGCCCGACCCCACTCTACCACGCCGCGCGGCTCAGCGAAAGGCAGGGCGGCGCCCAG
ATCTGGCTGAAGCGCGAAGACCTCTGCCACACCGGCGCGCACAAAATCAACAACGCACTCGGACAGGTGCTGCTCGCCAA
ACGCATGGGCAAAAAGCGCATCATCGCTGAAACCGGCGCGGGCCAGCACGGCGTGGCGACGGCCACCGTCTGCGCGCTCT
TTGGTCTCGACTGCATCGTCTATATGGGTGAAGAGGACATCCGCCGCCAGGCTCCGAACGTCGCGCGGATGAAGTTGCTC
GGCACGGAGGTTCGCCCGGTCACTGCGGGGAGCAGAACGCTCAAGGACGCCACCAGCGAAGCGATCCGCGACTGGATGAA
CAATCCCGAAGATACCTTCTACATCGTCGGTTCGGTTATCGGAATGCACCCGTATCCGATGATGGTGCGCGACTTCCAGT
CGGTCATCGGCCGCGAAACCCGTCGGCAGGTTGTTGAACAAGCAGGACGTCTGCCTGATGTAATTGTGGCCTGCGTTGGC
GGCGGTAGCAATGCCATCGGCATGTTCTACGAGTTCCTGCCGGATGCCAAAGAGGTCGAACTGATCGGCGTGGAAGCCGC
CGGAGAGGGACTCGAAGGCAGGCACGCCGCTTCGCTCTCCAAGGGCGAAATCGGCGTGTTGCACGGCGCAATGATGAAGC
TCTTGCAGGACGAGCACGGCCAGGTGCAGGAGGCGCACTCGATCTCCGCCGGTCTGGACTACCCAGGCGTCGGCCCGGAG
CATTGCTACCTGCAGAGGCTTGGGCTGGTCAGCTACACCTCAACAACGGACAAAGAAGCTCTTGCAGCACTCGACGCACT
GGCCAAAACCGAAGGAATCATCTGCGCCCTCGAATCGGCCCACGCCGTGCACTACGCCATGAAACGAGCCGCCGAAATGC
CGAAAGAGTCGATCATCGTGGTGAATCTCTCCGGAAGGGGTGACAAGGATATGGGCACCATCATGGATGAGCTGAAGCTG
TAA

Upstream 100 bases:

>100_bases
ATATTAAGGGCACGTTTCAGAACATCAAACTATTCAGGCATCGTCATCCGCGGCAACGCCGCATTCAGAGAACGATTCTC
AAAAAACTTCGCTACGCTCT

Downstream 100 bases:

>100_bases
AACTGAATCACGGCAATTCATGCTTGTAGGGGCAGCCCTTGCGGCTGCCCGGAATCAGCCGACAACAGAAGAGCGAGAAT
CTTGCAAGACAAAAAATCTT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQKVTYNAPDEFGHFGTFGGKFIPETLVKNAADLEEEYLKAKDDPEFRQTFDNLLRHYVGRPTPLYHAARLSERQGGAQ
IWLKREDLCHTGAHKINNALGQVLLAKRMGKKRIIAETGAGQHGVATATVCALFGLDCIVYMGEEDIRRQAPNVARMKLL
GTEVRPVTAGSRTLKDATSEAIRDWMNNPEDTFYIVGSVIGMHPYPMMVRDFQSVIGRETRRQVVEQAGRLPDVIVACVG
GGSNAIGMFYEFLPDAKEVELIGVEAAGEGLEGRHAASLSKGEIGVLHGAMMKLLQDEHGQVQEAHSISAGLDYPGVGPE
HCYLQRLGLVSYTSTTDKEALAALDALAKTEGIICALESAHAVHYAMKRAAEMPKESIIVVNLSGRGDKDMGTIMDELKL

Sequences:

>Translated_400_residues
MTQKVTYNAPDEFGHFGTFGGKFIPETLVKNAADLEEEYLKAKDDPEFRQTFDNLLRHYVGRPTPLYHAARLSERQGGAQ
IWLKREDLCHTGAHKINNALGQVLLAKRMGKKRIIAETGAGQHGVATATVCALFGLDCIVYMGEEDIRRQAPNVARMKLL
GTEVRPVTAGSRTLKDATSEAIRDWMNNPEDTFYIVGSVIGMHPYPMMVRDFQSVIGRETRRQVVEQAGRLPDVIVACVG
GGSNAIGMFYEFLPDAKEVELIGVEAAGEGLEGRHAASLSKGEIGVLHGAMMKLLQDEHGQVQEAHSISAGLDYPGVGPE
HCYLQRLGLVSYTSTTDKEALAALDALAKTEGIICALESAHAVHYAMKRAAEMPKESIIVVNLSGRGDKDMGTIMDELKL
>Mature_399_residues
TQKVTYNAPDEFGHFGTFGGKFIPETLVKNAADLEEEYLKAKDDPEFRQTFDNLLRHYVGRPTPLYHAARLSERQGGAQI
WLKREDLCHTGAHKINNALGQVLLAKRMGKKRIIAETGAGQHGVATATVCALFGLDCIVYMGEEDIRRQAPNVARMKLLG
TEVRPVTAGSRTLKDATSEAIRDWMNNPEDTFYIVGSVIGMHPYPMMVRDFQSVIGRETRRQVVEQAGRLPDVIVACVGG
GSNAIGMFYEFLPDAKEVELIGVEAAGEGLEGRHAASLSKGEIGVLHGAMMKLLQDEHGQVQEAHSISAGLDYPGVGPEH
CYLQRLGLVSYTSTTDKEALAALDALAKTEGIICALESAHAVHYAMKRAAEMPKESIIVVNLSGRGDKDMGTIMDELKL

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=387, Percent_Identity=53.7467700258398, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321412, Length=385, Percent_Identity=55.5844155844156, Blast_Score=429, Evalue=1e-121,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43679; Mature: 43547

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKVTYNAPDEFGHFGTFGGKFIPETLVKNAADLEEEYLKAKDDPEFRQTFDNLLRHYV
CCCCEECCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
GRPTPLYHAARLSERQGGAQIWLKREDLCHTGAHKINNALGQVLLAKRMGKKRIIAETGA
CCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GQHGVATATVCALFGLDCIVYMGEEDIRRQAPNVARMKLLGTEVRPVTAGSRTLKDATSE
CCCCHHHHHHHHHHHHHHEEEECCHHHHHCCCCHHHHHHHCCCCCEECCCCHHHHHHHHH
AIRDWMNNPEDTFYIVGSVIGMHPYPMMVRDFQSVIGRETRRQVVEQAGRLPDVIVACVG
HHHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEC
GGSNAIGMFYEFLPDAKEVELIGVEAAGEGLEGRHAASLSKGEIGVLHGAMMKLLQDEHG
CCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCC
QVQEAHSISAGLDYPGVGPEHCYLQRLGLVSYTSTTDKEALAALDALAKTEGIICALESA
HHHHHHHHHCCCCCCCCCHHHHHHHHHCHHEECCCCHHHHHHHHHHHHHCCCEEEEEHHH
HAVHYAMKRAAEMPKESIIVVNLSGRGDKDMGTIMDELKL
HHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TQKVTYNAPDEFGHFGTFGGKFIPETLVKNAADLEEEYLKAKDDPEFRQTFDNLLRHYV
CCCEECCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
GRPTPLYHAARLSERQGGAQIWLKREDLCHTGAHKINNALGQVLLAKRMGKKRIIAETGA
CCCCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GQHGVATATVCALFGLDCIVYMGEEDIRRQAPNVARMKLLGTEVRPVTAGSRTLKDATSE
CCCCHHHHHHHHHHHHHHEEEECCHHHHHCCCCHHHHHHHCCCCCEECCCCHHHHHHHHH
AIRDWMNNPEDTFYIVGSVIGMHPYPMMVRDFQSVIGRETRRQVVEQAGRLPDVIVACVG
HHHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEC
GGSNAIGMFYEFLPDAKEVELIGVEAAGEGLEGRHAASLSKGEIGVLHGAMMKLLQDEHG
CCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHCC
QVQEAHSISAGLDYPGVGPEHCYLQRLGLVSYTSTTDKEALAALDALAKTEGIICALESA
HHHHHHHHHCCCCCCCCCHHHHHHHHHCHHEECCCCHHHHHHHHHHHHHCCCEEEEEHHH
HAVHYAMKRAAEMPKESIIVVNLSGRGDKDMGTIMDELKL
HHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]