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The map label for this gene is acoC [H]

Identifier: 193213020

GI number: 193213020

Start: 1487555

End: 1488448

Strand: Direct

Name: acoC [H]

Synonym: Cpar_1371

Alternate gene names: 193213020

Gene position: 1487555-1488448 (Clockwise)

Preceding gene: 193213017

Following gene: 193213022

Centisome position: 64.98

GC content: 57.83

Gene sequence:

>894_bases
ATGGGCTCCCTGCCCCAATTCGGCACAACAATGGCATCGAAAGACCGCTGGTTCATCTGGCAATTCTCGGACAAAGACGA
AGCAAAAATCCGCTATCGGGAGTACGGCCCGGCTGACTCACCCCACACGCCATTGCTGTTCGTTCACGGTTATGGCGGCA
TGATCGAGCACTGGAACGACAACATTCCGGCGTTTTCGGACAGGTACAGAATCTACGCGATGGACCTGATCGGTTTCGGC
CAGTCCACCAAGCCCAACGTACGGTACTGCCTGGAACTGTTCGCTGCCCAGATCAAGGCGTTCATGCACCTGAAAAAGCT
CGACAAAATCATTCTGGTGGGTCACTCGATGGGCGGGGCGGGCAGCGTCATCTATGCGCATCTGAATCCGGAAAGGGTTC
GCGGGCTGATTCTGGCCAACCCCTCCGGCCTGTATGGAGACAGCATGGACGGCATGGCCAAAGCTTTCTTCGGACTGGTC
GGCTCACCGCTGATCGGCGAAATGCTTTTCGCGGCGTTCGCAAACCCGGTCGGCGTCAGCCAGAGCCTCACCCCGACCTA
CTACAACCAGAAAAAGGTCGATCTGAACCTGATCAACCAGTTTTCACGCCCACTTCCGGATCGAGGCGCAATGTTTTCGT
ACCTGTCGCCGTCGAAACGACCGCACGACTTCATGCTCGAGGGCATCAAGCCCTGCAACTACAAGGGCGATGCCTGGCTG
ATGTGGGGCGCGGAAGATACCGCGCTGCCACCGCACAAAATCATTCCGGAATTCCAGGAGTTGCTTCCGCAGGCAGGCGC
CTACATCATTCCGAAAGCGGGTCACTGCATCCACCACGACGCGCACGAAACCTTCAACGCACGCCTCGCCCACATTCTCG
GGCGTCTGGAGTGA

Upstream 100 bases:

>100_bases
GTTTTGTAAAACAGGATAAACCAACACCTGTTTCAGGAAATTCCCCGATCCGCTTTTAATTCTTGCCGGAACCGCTATAT
CTTGCCTTCAAAAGTCTTCA

Downstream 100 bases:

>100_bases
GCTATGCTACAAGCCTGATGTGGTATTGCCGCTGGTGGCCTGCACCTTGAGGTACTTGAGCTGGGCAGGCTTCATGGCTA
TCTGCAAGAGGTAGCCCTCA

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MGSLPQFGTTMASKDRWFIWQFSDKDEAKIRYREYGPADSPHTPLLFVHGYGGMIEHWNDNIPAFSDRYRIYAMDLIGFG
QSTKPNVRYCLELFAAQIKAFMHLKKLDKIILVGHSMGGAGSVIYAHLNPERVRGLILANPSGLYGDSMDGMAKAFFGLV
GSPLIGEMLFAAFANPVGVSQSLTPTYYNQKKVDLNLINQFSRPLPDRGAMFSYLSPSKRPHDFMLEGIKPCNYKGDAWL
MWGAEDTALPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNARLAHILGRLE

Sequences:

>Translated_297_residues
MGSLPQFGTTMASKDRWFIWQFSDKDEAKIRYREYGPADSPHTPLLFVHGYGGMIEHWNDNIPAFSDRYRIYAMDLIGFG
QSTKPNVRYCLELFAAQIKAFMHLKKLDKIILVGHSMGGAGSVIYAHLNPERVRGLILANPSGLYGDSMDGMAKAFFGLV
GSPLIGEMLFAAFANPVGVSQSLTPTYYNQKKVDLNLINQFSRPLPDRGAMFSYLSPSKRPHDFMLEGIKPCNYKGDAWL
MWGAEDTALPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNARLAHILGRLE
>Mature_296_residues
GSLPQFGTTMASKDRWFIWQFSDKDEAKIRYREYGPADSPHTPLLFVHGYGGMIEHWNDNIPAFSDRYRIYAMDLIGFGQ
STKPNVRYCLELFAAQIKAFMHLKKLDKIILVGHSMGGAGSVIYAHLNPERVRGLILANPSGLYGDSMDGMAKAFFGLVG
SPLIGEMLFAAFANPVGVSQSLTPTYYNQKKVDLNLINQFSRPLPDRGAMFSYLSPSKRPHDFMLEGIKPCNYKGDAWLM
WGAEDTALPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNARLAHILGRLE

Specific function: Unknown

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=123, Percent_Identity=32.520325203252, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146278, Length=266, Percent_Identity=25.9398496240602, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32566936, Length=111, Percent_Identity=34.2342342342342, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17558492, Length=111, Percent_Identity=34.2342342342342, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24586385, Length=121, Percent_Identity=37.1900826446281, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24586387, Length=121, Percent_Identity=37.1900826446281, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24586391, Length=121, Percent_Identity=37.1900826446281, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24586389, Length=121, Percent_Identity=37.1900826446281, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 33274; Mature: 33143

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLPQFGTTMASKDRWFIWQFSDKDEAKIRYREYGPADSPHTPLLFVHGYGGMIEHWND
CCCCCCCCCHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHCCC
NIPAFSDRYRIYAMDLIGFGQSTKPNVRYCLELFAAQIKAFMHLKKLDKIILVGHSMGGA
CCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCC
GSVIYAHLNPERVRGLILANPSGLYGDSMDGMAKAFFGLVGSPLIGEMLFAAFANPVGVS
CCEEEEECCHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
QSLTPTYYNQKKVDLNLINQFSRPLPDRGAMFSYLSPSKRPHDFMLEGIKPCNYKGDAWL
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEHHCCCCCCCHHHHHCCCCCCCCCCCEEE
MWGAEDTALPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNARLAHILGRLE
EECCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSLPQFGTTMASKDRWFIWQFSDKDEAKIRYREYGPADSPHTPLLFVHGYGGMIEHWND
CCCCCCCCHHCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHCCC
NIPAFSDRYRIYAMDLIGFGQSTKPNVRYCLELFAAQIKAFMHLKKLDKIILVGHSMGGA
CCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCC
GSVIYAHLNPERVRGLILANPSGLYGDSMDGMAKAFFGLVGSPLIGEMLFAAFANPVGVS
CCEEEEECCHHHHCEEEEECCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCC
QSLTPTYYNQKKVDLNLINQFSRPLPDRGAMFSYLSPSKRPHDFMLEGIKPCNYKGDAWL
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEHHCCCCCCCHHHHHCCCCCCCCCCCEEE
MWGAEDTALPPHKIIPEFQELLPQAGAYIIPKAGHCIHHDAHETFNARLAHILGRLE
EECCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7813883 [H]