Click here to switch to the map view.

The map label for this gene is ampG [H]

Identifier: 192289053

GI number: 192289053

Start: 676650

End: 678029

Strand: Reverse

Name: ampG [H]

Synonym: Rpal_0623

Alternate gene names: 192289053

Gene position: 678029-676650 (Counterclockwise)

Preceding gene: 192289054

Following gene: 192289048

Centisome position: 11.8

GC content: 67.17

Gene sequence:

>1380_bases
ATGACCAGCCCTACTGCCGGCCTGCCAGAGGCCGATCCCGCCGCTCCGCAGATCTCCACCAAGCCGAGCTGGCGCGAGGC
GATGGCGGTGTACTTACAGCCGCGGGTGCTGGTGGTGCTGTTCCTCGGGTTCTCGTCGGGGCTGCCGCTGGCGCTGTCCG
GCTCGACCCTATTGGTATGGATGCGGGAGTCCGGCGTCGACCTCGGCACGATCGGCCTGTTCGCGCTGGTCGGCACGCCC
TACACGCTGAAGTTCATCTGGGCGCCGCTGGTCGATGCGCTGCACGTGCCGCTGTTCACCAGAGCATTCGGACGCCGCCG
CGGCTGGCTGGTGTTCGTCCAACTGCTGCTGATCGCCGCGATCCTGCTGCTGGCGCTTACCGATCCGGCGAAGTCGCCAC
TGTATGTGGCGATCGGCGCGCTGCTGGTCGCCACCGCCTCGGCGACCCAGGACATCGTGGTCGACGCGTTCCGGGTCGAG
AGCCTGCCGGAAGAGGAACAGGCTGCCGGCATGGCGTCCTACGTGGCTGCCTACCGCATCGGCATGTTGATCTCCACCGC
CGGCGTGCTGTTCCTGGTCAGCGCTTATGAAGGTACCGGACTGACCCGGACCACCGCATGGATGTGGGGCTATGTGACGA
TGGCCGCGATGGTGCTGATCGGCACCGTCACCGCGCTGCTCGCCACCGAGCCGGAACAGTCGCGCCGCGCCGAAGCAGCG
ACCAGCGGCGAGAGCGCATTGAAGCGGGTGATCCACGCCGCTCTGGGGGCGTTCACCGAATTTCTCACCCGCAAGGACGC
GCTCACCGCCCTCGCCTTCGTGGTGCTGTTCAAGTTCACCGATGCATTTTCCGGCACCATGACGGCGCCGTTCGTGATCG
ATCTCGGCTATTCGCGCAATGATTATGCGGCAATCGTGAAGGGCGTCGGGCTGGCGGCGACGCTGATCGGCGGCTTCGCC
GGCGGTTATCTGGCGCGGCGCTATTCGCTGGTGGCGAGCCTATGGATCGGCGCGGTGCTGCAGGCGGTGTCGAACCTGGC
GTTCGCCTGGCTGTCGACCGTCGGCGTCAACCAATGGGCGCTGGCGCTGGCGATCTCGGTGGAGAATTTCACCGGCGCGA
TCGGCACCGTGATTTTCGTCGCGTATCTGTCGGCGCTGTGCCAGAACCCGCTGCACACTGCGACGCAATACGCGCTGCTC
ACCGCCCTCGCCGCCGTCGGCCGCACCTACCTGTCGGCGAGTGCCGGATACGTCGCGCAGGCCACCGGCTGGCCGGCGTT
CTTCACCATCAGCGTTGCGGTCGCGGCGCCGAGCTTGGTGCTCCTGGCGTGGCTGCAACGCCGCGGCCATTTCGCCGCGC
TCGGACCGGTGAAGGTTTAG

Upstream 100 bases:

>100_bases
AGCTTCCGGATCGATGAAATGACGCGGAGCTGACGCAGCCCGCTCGGGCGGCGACACCGGGCCGTCCGCCCGGTGTCGCC
GAATCGGATAGGTTCATCCC

Downstream 100 bases:

>100_bases
GCGCCGCCCGCTCCTCGCAACGCCGACGAGAGCCCGTCGCTTACTTCACCAGACTCCATTTCGTCACCACCGCCTCGCTC
ATCTGGCCGGGCTCGTTGGC

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MTSPTAGLPEADPAAPQISTKPSWREAMAVYLQPRVLVVLFLGFSSGLPLALSGSTLLVWMRESGVDLGTIGLFALVGTP
YTLKFIWAPLVDALHVPLFTRAFGRRRGWLVFVQLLLIAAILLLALTDPAKSPLYVAIGALLVATASATQDIVVDAFRVE
SLPEEEQAAGMASYVAAYRIGMLISTAGVLFLVSAYEGTGLTRTTAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAA
TSGESALKRVIHAALGAFTEFLTRKDALTALAFVVLFKFTDAFSGTMTAPFVIDLGYSRNDYAAIVKGVGLAATLIGGFA
GGYLARRYSLVASLWIGAVLQAVSNLAFAWLSTVGVNQWALALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALL
TALAAVGRTYLSASAGYVAQATGWPAFFTISVAVAAPSLVLLAWLQRRGHFAALGPVKV

Sequences:

>Translated_459_residues
MTSPTAGLPEADPAAPQISTKPSWREAMAVYLQPRVLVVLFLGFSSGLPLALSGSTLLVWMRESGVDLGTIGLFALVGTP
YTLKFIWAPLVDALHVPLFTRAFGRRRGWLVFVQLLLIAAILLLALTDPAKSPLYVAIGALLVATASATQDIVVDAFRVE
SLPEEEQAAGMASYVAAYRIGMLISTAGVLFLVSAYEGTGLTRTTAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAA
TSGESALKRVIHAALGAFTEFLTRKDALTALAFVVLFKFTDAFSGTMTAPFVIDLGYSRNDYAAIVKGVGLAATLIGGFA
GGYLARRYSLVASLWIGAVLQAVSNLAFAWLSTVGVNQWALALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALL
TALAAVGRTYLSASAGYVAQATGWPAFFTISVAVAAPSLVLLAWLQRRGHFAALGPVKV
>Mature_458_residues
TSPTAGLPEADPAAPQISTKPSWREAMAVYLQPRVLVVLFLGFSSGLPLALSGSTLLVWMRESGVDLGTIGLFALVGTPY
TLKFIWAPLVDALHVPLFTRAFGRRRGWLVFVQLLLIAAILLLALTDPAKSPLYVAIGALLVATASATQDIVVDAFRVES
LPEEEQAAGMASYVAAYRIGMLISTAGVLFLVSAYEGTGLTRTTAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAAT
SGESALKRVIHAALGAFTEFLTRKDALTALAFVVLFKFTDAFSGTMTAPFVIDLGYSRNDYAAIVKGVGLAATLIGGFAG
GYLARRYSLVASLWIGAVLQAVSNLAFAWLSTVGVNQWALALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLT
ALAAVGRTYLSASAGYVAQATGWPAFFTISVAVAAPSLVLLAWLQRRGHFAALGPVKV

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI300360496, Length=211, Percent_Identity=29.8578199052133, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI4757708, Length=211, Percent_Identity=29.8578199052133, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786636, Length=418, Percent_Identity=38.9952153110048, Blast_Score=269, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24665528, Length=315, Percent_Identity=26.3492063492064, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24665524, Length=315, Percent_Identity=26.3492063492064, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48482; Mature: 48351

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPTAGLPEADPAAPQISTKPSWREAMAVYLQPRVLVVLFLGFSSGLPLALSGSTLLVW
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCCEEEEE
MRESGVDLGTIGLFALVGTPYTLKFIWAPLVDALHVPLFTRAFGRRRGWLVFVQLLLIAA
EECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ILLLALTDPAKSPLYVAIGALLVATASATQDIVVDAFRVESLPEEEQAAGMASYVAAYRI
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GMLISTAGVLFLVSAYEGTGLTRTTAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAA
HHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TSGESALKRVIHAALGAFTEFLTRKDALTALAFVVLFKFTDAFSGTMTAPFVIDLGYSRN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
DYAAIVKGVGLAATLIGGFAGGYLARRYSLVASLWIGAVLQAVSNLAFAWLSTVGVNQWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLTALAAVGRTYLSASAGYVAQ
EEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ATGWPAFFTISVAVAAPSLVLLAWLQRRGHFAALGPVKV
CCCCCCHHEEHHHHHHHHHHHHHHHHHCCCEEECCCCCC
>Mature Secondary Structure 
TSPTAGLPEADPAAPQISTKPSWREAMAVYLQPRVLVVLFLGFSSGLPLALSGSTLLVW
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCCEEEEE
MRESGVDLGTIGLFALVGTPYTLKFIWAPLVDALHVPLFTRAFGRRRGWLVFVQLLLIAA
EECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ILLLALTDPAKSPLYVAIGALLVATASATQDIVVDAFRVESLPEEEQAAGMASYVAAYRI
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GMLISTAGVLFLVSAYEGTGLTRTTAWMWGYVTMAAMVLIGTVTALLATEPEQSRRAEAA
HHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TSGESALKRVIHAALGAFTEFLTRKDALTALAFVVLFKFTDAFSGTMTAPFVIDLGYSRN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
DYAAIVKGVGLAATLIGGFAGGYLARRYSLVASLWIGAVLQAVSNLAFAWLSTVGVNQWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LALAISVENFTGAIGTVIFVAYLSALCQNPLHTATQYALLTALAAVGRTYLSASAGYVAQ
EEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ATGWPAFFTISVAVAAPSLVLLAWLQRRGHFAALGPVKV
CCCCCCHHEEHHHHHHHHHHHHHHHHHCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]