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The map label for this gene is regA [H]

Identifier: 192289004

GI number: 192289004

Start: 622923

End: 623477

Strand: Reverse

Name: regA [H]

Synonym: Rpal_0574

Alternate gene names: 192289004

Gene position: 623477-622923 (Counterclockwise)

Preceding gene: 192289005

Following gene: 192289002

Centisome position: 10.85

GC content: 67.39

Gene sequence:

>555_bases
GTGAACGCCATTCCCGAACTGAATGACCACACCGATCGCTCGCTGCTGATCGTGGAGGATGACAAGCCGTTCCTCGACCG
GCTGGCCCGGGCGATGGAAACGCGCGGCTTCGCGGTCACGGCTTGCGACAGCGTCTCCAGCGGTCTCGCCCAGATCGGCA
AGGCGGCGCCGGCGTTTGCGGTGGTCGATCTTCGCCTCGGCGACGGCAATGGCCTCGATGTCGTCTCGGCGCTGAAGCGT
GAGCGCCCCGATTGCCGCGCTATCGTGCTGACCGGCTACGGCAACATCGCCACCGCGGTCACCGCCGTGAAGATGGGCGC
AGTGGACTATCTGTCGAAGCCTGCGGACGCCGACGACGTCGTCGCTGCGTTGCTCTCGACCGGCACCGAGAAATCCGAAC
CGCCGCCGAACCCGATGTCGGCCGACCGCGTCCGCTGGGAGCACATCCAGCGCATCTACGAGATGTGCAACCGCAACGTC
TCCGAGACCGCGCGCCGCCTCAACATGCACCGCCGCACCCTGCAGCGCATCCTCGCCAAGCGCGCGCCGCGGTAA

Upstream 100 bases:

>100_bases
ATGGCTTGATCTGCCCCGCGCGCTCCGGTCGCAGGCTTTCGCTCTTGGCAGCGCGATGTCGCACCCCCATATCTTGTGAC
ACTCGACGAGGAGCCACGCC

Downstream 100 bases:

>100_bases
GTCCAGCTCTCTGCCGATGATCAGCGCGGTCATTCCGGGGCGCTCGCAAAGCGAGCGAACCCGGAATCCGACACGCGACG
AATCCATCGAGATTCAGGGT

Product: Fis family transcriptional regulator

Products: NA

Alternate protein names: Response regulator prrA [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNAIPELNDHTDRSLLIVEDDKPFLDRLARAMETRGFAVTACDSVSSGLAQIGKAAPAFAVVDLRLGDGNGLDVVSALKR
ERPDCRAIVLTGYGNIATAVTAVKMGAVDYLSKPADADDVVAALLSTGTEKSEPPPNPMSADRVRWEHIQRIYEMCNRNV
SETARRLNMHRRTLQRILAKRAPR

Sequences:

>Translated_184_residues
MNAIPELNDHTDRSLLIVEDDKPFLDRLARAMETRGFAVTACDSVSSGLAQIGKAAPAFAVVDLRLGDGNGLDVVSALKR
ERPDCRAIVLTGYGNIATAVTAVKMGAVDYLSKPADADDVVAALLSTGTEKSEPPPNPMSADRVRWEHIQRIYEMCNRNV
SETARRLNMHRRTLQRILAKRAPR
>Mature_184_residues
MNAIPELNDHTDRSLLIVEDDKPFLDRLARAMETRGFAVTACDSVSSGLAQIGKAAPAFAVVDLRLGDGNGLDVVSALKR
ERPDCRAIVLTGYGNIATAVTAVKMGAVDYLSKPADADDVVAALLSTGTEKSEPPPNPMSADRVRWEHIQRIYEMCNRNV
SETARRLNMHRRTLQRILAKRAPR

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=125, Percent_Identity=28.8, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=29.5652173913043, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=28.4552845528455, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=28.9473684210526, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20139; Mature: 20139

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIPELNDHTDRSLLIVEDDKPFLDRLARAMETRGFAVTACDSVSSGLAQIGKAAPAFA
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCEE
VVDLRLGDGNGLDVVSALKRERPDCRAIVLTGYGNIATAVTAVKMGAVDYLSKPADADDV
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VAALLSTGTEKSEPPPNPMSADRVRWEHIQRIYEMCNRNVSETARRLNMHRRTLQRILAK
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RAPR
CCCC
>Mature Secondary Structure
MNAIPELNDHTDRSLLIVEDDKPFLDRLARAMETRGFAVTACDSVSSGLAQIGKAAPAFA
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCCCEE
VVDLRLGDGNGLDVVSALKRERPDCRAIVLTGYGNIATAVTAVKMGAVDYLSKPADADDV
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VAALLSTGTEKSEPPPNPMSADRVRWEHIQRIYEMCNRNVSETARRLNMHRRTLQRILAK
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RAPR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181698; 8282708 [H]