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The map label for this gene is regB [H]

Identifier: 192289005

GI number: 192289005

Start: 623569

End: 624891

Strand: Reverse

Name: regB [H]

Synonym: Rpal_0575

Alternate gene names: 192289005

Gene position: 624891-623569 (Counterclockwise)

Preceding gene: 192289010

Following gene: 192289004

Centisome position: 10.88

GC content: 66.67

Gene sequence:

>1323_bases
ATGTCCGATGATCTGATTTCCGCCGACTTCCGGCACCCGCGGCGCCATGTTCGCCTCGATACCATCCTGCGACTGCGCTG
GCTGGCGGCGCTCGGCCAGCTCTCCGCGATCTTCGTGGTCTCGGAAGGGCTGGAATTCGACTTCGCGGTCATGCCGTGCA
TCGTCATCATCGCCGTGTCGGGCCTGGTCAATCTCGCGCTGCAGATCGCCTTCAATCCGATGCAGCGGATGGAGCCGATC
TACGCCGCGCTGCTGCTCGCGCTCAACATCTCCGAGCTGGCGGGCCTGTTGTACTTTACCGGCGGCCTGCAGAACCCGTT
CGCGTTCCTGTTCCTCGGCCCGGTGCTGATCAGCGCCACCGCGCTGCCGACCCGGATGACGATCTCGCTCGGGATCTTCG
CGGCCGGCTGCGCGGCGTTCCTCGGCTACAGCCATCTGCCGCTGCCCTGGGCCGGCGAGGAGCCGGTGGCGCTGCCGCGG
ATCTATCTGGTCGGGGTCTGGCTCTCGATCCTGCTCGCGATCGGCGTCACCAGCCTCTACACCTTCCAGGTCACCGAAGA
GGCCCGCAAGCTCGCCGATGCGCTGTCGGCCGCCGAACTGGTGCTGGAGCGCGAGCAGCATCTGACCCAGCTCGATGGCC
TCGCCGCCGCGGCCGCACACGAACTCGGCACGCCGCTGTCGACCATCTTCCTGATCTCGCGCGAGCTGGAGAAAACCGCG
CCGCCTGAGATGGCCTCCGACCTGCGGACGCTGCGAGAACAGGCGCAGCGCTGCCGGGAGATCCTCGGCAAGATCGCCCA
GCTGTCGTCGGCCGGCGCGCCGTTCGACCGGATGCCGCTGTCGACGTTGATCGAGGAAGCAGTGGCGCCGCATCGCGACT
TCGGCATCGCCATCAAGATCCGGCTGGCGCAGCACGGCGAACCCGAGCCGGTGGTGATGCGCAACCCCGCGATCCTGTAC
GGCATCGGCAATATCCTGGAGAATGCGGTCGACTTCGCCCGCACCGCCGTCGAGGTGAATGCCTGGTGGAATGCCGAGAC
CGTGCAGATCGTGGTGTCGGACGACGGACCCGGCATCAAGCCGGACGTGCTGCGCCGGATCGGCGAGCCTTATCTGTCCC
GCCGCCGCAGTGCCGACGATCCCAATCGTGAGCGCTCCGGGCTCGGCCTCGGCGTGTTCATCGCCCGGACCCTGCTGGAG
CGAACCGGTGCCAAGGTCGAGTTCCGCAACAAGACCTTCCCGGATCACGGTGCCATCGTCCAGCTCAGCTGGCCCAGGAA
CCGCTTCGAGACCATCGAAAAGACCGAAGAAACAATGGCTTGA

Upstream 100 bases:

>100_bases
GTTTGGCGATTGCCGGCCGAGAGCGCAAGCTTGCCGCCGGGCGATCCGCCGCGGGCGGCGTCAATTGGCATCCCGTTGCG
CCGACGCTACTGTCCGGCGC

Downstream 100 bases:

>100_bases
TCTGCCCCGCGCGCTCCGGTCGCAGGCTTTCGCTCTTGGCAGCGCGATGTCGCACCCCCATATCTTGTGACACTCGACGA
GGAGCCACGCCGTGAACGCC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSDDLISADFRHPRRHVRLDTILRLRWLAALGQLSAIFVVSEGLEFDFAVMPCIVIIAVSGLVNLALQIAFNPMQRMEPI
YAALLLALNISELAGLLYFTGGLQNPFAFLFLGPVLISATALPTRMTISLGIFAAGCAAFLGYSHLPLPWAGEEPVALPR
IYLVGVWLSILLAIGVTSLYTFQVTEEARKLADALSAAELVLEREQHLTQLDGLAAAAAHELGTPLSTIFLISRELEKTA
PPEMASDLRTLREQAQRCREILGKIAQLSSAGAPFDRMPLSTLIEEAVAPHRDFGIAIKIRLAQHGEPEPVVMRNPAILY
GIGNILENAVDFARTAVEVNAWWNAETVQIVVSDDGPGIKPDVLRRIGEPYLSRRRSADDPNRERSGLGLGVFIARTLLE
RTGAKVEFRNKTFPDHGAIVQLSWPRNRFETIEKTEETMA

Sequences:

>Translated_440_residues
MSDDLISADFRHPRRHVRLDTILRLRWLAALGQLSAIFVVSEGLEFDFAVMPCIVIIAVSGLVNLALQIAFNPMQRMEPI
YAALLLALNISELAGLLYFTGGLQNPFAFLFLGPVLISATALPTRMTISLGIFAAGCAAFLGYSHLPLPWAGEEPVALPR
IYLVGVWLSILLAIGVTSLYTFQVTEEARKLADALSAAELVLEREQHLTQLDGLAAAAAHELGTPLSTIFLISRELEKTA
PPEMASDLRTLREQAQRCREILGKIAQLSSAGAPFDRMPLSTLIEEAVAPHRDFGIAIKIRLAQHGEPEPVVMRNPAILY
GIGNILENAVDFARTAVEVNAWWNAETVQIVVSDDGPGIKPDVLRRIGEPYLSRRRSADDPNRERSGLGLGVFIARTLLE
RTGAKVEFRNKTFPDHGAIVQLSWPRNRFETIEKTEETMA
>Mature_439_residues
SDDLISADFRHPRRHVRLDTILRLRWLAALGQLSAIFVVSEGLEFDFAVMPCIVIIAVSGLVNLALQIAFNPMQRMEPIY
AALLLALNISELAGLLYFTGGLQNPFAFLFLGPVLISATALPTRMTISLGIFAAGCAAFLGYSHLPLPWAGEEPVALPRI
YLVGVWLSILLAIGVTSLYTFQVTEEARKLADALSAAELVLEREQHLTQLDGLAAAAAHELGTPLSTIFLISRELEKTAP
PEMASDLRTLREQAQRCREILGKIAQLSSAGAPFDRMPLSTLIEEAVAPHRDFGIAIKIRLAQHGEPEPVVMRNPAILYG
IGNILENAVDFARTAVEVNAWWNAETVQIVVSDDGPGIKPDVLRRIGEPYLSRRRSADDPNRERSGLGLGVFIARTLLER
TGAKVEFRNKTFPDHGAIVQLSWPRNRFETIEKTEETMA

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=26.953125, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48373; Mature: 48242

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDLISADFRHPRRHVRLDTILRLRWLAALGQLSAIFVVSEGLEFDFAVMPCIVIIAVS
CCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHH
GLVNLALQIAFNPMQRMEPIYAALLLALNISELAGLLYFTGGLQNPFAFLFLGPVLISAT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ALPTRMTISLGIFAAGCAAFLGYSHLPLPWAGEEPVALPRIYLVGVWLSILLAIGVTSLY
CCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
TFQVTEEARKLADALSAAELVLEREQHLTQLDGLAAAAAHELGTPLSTIFLISRELEKTA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
PPEMASDLRTLREQAQRCREILGKIAQLSSAGAPFDRMPLSTLIEEAVAPHRDFGIAIKI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEE
RLAQHGEPEPVVMRNPAILYGIGNILENAVDFARTAVEVNAWWNAETVQIVVSDDGPGIK
EEECCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEECCCCCCC
PDVLRRIGEPYLSRRRSADDPNRERSGLGLGVFIARTLLERTGAKVEFRNKTFPDHGAIV
HHHHHHCCCHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEE
QLSWPRNRFETIEKTEETMA
EEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDDLISADFRHPRRHVRLDTILRLRWLAALGQLSAIFVVSEGLEFDFAVMPCIVIIAVS
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHH
GLVNLALQIAFNPMQRMEPIYAALLLALNISELAGLLYFTGGLQNPFAFLFLGPVLISAT
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
ALPTRMTISLGIFAAGCAAFLGYSHLPLPWAGEEPVALPRIYLVGVWLSILLAIGVTSLY
CCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHE
TFQVTEEARKLADALSAAELVLEREQHLTQLDGLAAAAAHELGTPLSTIFLISRELEKTA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
PPEMASDLRTLREQAQRCREILGKIAQLSSAGAPFDRMPLSTLIEEAVAPHRDFGIAIKI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEE
RLAQHGEPEPVVMRNPAILYGIGNILENAVDFARTAVEVNAWWNAETVQIVVSDDGPGIK
EEECCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEECCCCCCC
PDVLRRIGEPYLSRRRSADDPNRERSGLGLGVFIARTLLERTGAKVEFRNKTFPDHGAIV
HHHHHHCCCHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCEE
QLSWPRNRFETIEKTEETMA
EEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]