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The map label for this gene is dapA [H]

Identifier: 190894982

GI number: 190894982

Start: 701569

End: 702447

Strand: Reverse

Name: dapA [H]

Synonym: RHECIAT_PC0000648

Alternate gene names: 190894982

Gene position: 702447-701569 (Counterclockwise)

Preceding gene: 190894983

Following gene: 190894981

Centisome position: 64.35

GC content: 60.41

Gene sequence:

>879_bases
ATGAAACTTTCCGGCGTCATACCCGCCCTCATCACCCCCTTCGACGCGAACAACAGGATCGACTTCAAGGCGTTCGAGAA
GCTTCTGACGCATCTGCGCGAGGCAGGCGTCACCGGCTGGGTGCCGAACGGCTCGACCGGCGAATATTTCAGCCAATCCA
GGGAAGAGCGCCGTGACGTGCTGCAGTTCGTCAAGGAGTTTGCCAGGCCCGGCGAAATCCTGATCGCCGGCACCAATGCG
CCCGCGACCCGCGAGGTGATCGAGCAGACGGCGCTCGCCAGAGATATCGGCTATGACACCGTCCTGCTGGCACCGCCCTT
TTATACCCGTCCAACCCAGGCGGAACTGATCAGGCACTATGAATCCGTGCTTGGGGCCGTCGATGTGAACCTCGTCCTCT
ATTCTTATCCGGCTAAGGATGGTTCAGACATCAGCTTCGAGCTGATGGATCATTTTGCCGACAATCCGCGGGTGATCGGC
ATCAAGGAAAGCTCGGGTGTATTGCAGCGGGCGATCGACATCGCCAGCCGCTATGAGGGCAAGATCCAGCTCGTCAGCGG
CTCCGACGATATCGCGCTCGATTTCATGTTCTGGGGCGCGGAAAGCTGGATCTGCGGCCCGTCCAACTGCATGGCCAAGG
CCTGCTGCGATCTCGACCGAACCTACAAGGCGGGAGATCTAAGCAAGGCGCGCGAGATGATGAAGACCCTCTATCGGGCG
ATGAACATCCTCGAAAGCGGCAAGTTCGTGCAGAAGATCAAGTATGGCTGCGAGCTGCAGGGCTTGTCCGTGGGGACGTG
CCGCGCGCCGCTCGGCGAGCTGACCGCGGAGGAAAAGGCCGAGTTCAGGGCGGCGATGGAGCCGATCCTCAACTGGTAG

Upstream 100 bases:

>100_bases
CATCGCCTTCCCCCTCACGCGGGCGGTCTCCCTCATGGAGGGACGCATTCTCAAGAAGCTCGCAATCTGAAAACCGTCGT
TCCCAGGACAGGAGAATCCC

Downstream 100 bases:

>100_bases
GATTTTTCACGTCGATACCGGGGTCGGCCGGAGGCAGGCCGGTCCCGAACATACTCATGGTTCCCAGGAAAGACCCGGAG
ACTCAAGCGATGCGATTCAA

Product: putative dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKLSGVIPALITPFDANNRIDFKAFEKLLTHLREAGVTGWVPNGSTGEYFSQSREERRDVLQFVKEFARPGEILIAGTNA
PATREVIEQTALARDIGYDTVLLAPPFYTRPTQAELIRHYESVLGAVDVNLVLYSYPAKDGSDISFELMDHFADNPRVIG
IKESSGVLQRAIDIASRYEGKIQLVSGSDDIALDFMFWGAESWICGPSNCMAKACCDLDRTYKAGDLSKAREMMKTLYRA
MNILESGKFVQKIKYGCELQGLSVGTCRAPLGELTAEEKAEFRAAMEPILNW

Sequences:

>Translated_292_residues
MKLSGVIPALITPFDANNRIDFKAFEKLLTHLREAGVTGWVPNGSTGEYFSQSREERRDVLQFVKEFARPGEILIAGTNA
PATREVIEQTALARDIGYDTVLLAPPFYTRPTQAELIRHYESVLGAVDVNLVLYSYPAKDGSDISFELMDHFADNPRVIG
IKESSGVLQRAIDIASRYEGKIQLVSGSDDIALDFMFWGAESWICGPSNCMAKACCDLDRTYKAGDLSKAREMMKTLYRA
MNILESGKFVQKIKYGCELQGLSVGTCRAPLGELTAEEKAEFRAAMEPILNW
>Mature_292_residues
MKLSGVIPALITPFDANNRIDFKAFEKLLTHLREAGVTGWVPNGSTGEYFSQSREERRDVLQFVKEFARPGEILIAGTNA
PATREVIEQTALARDIGYDTVLLAPPFYTRPTQAELIRHYESVLGAVDVNLVLYSYPAKDGSDISFELMDHFADNPRVIG
IKESSGVLQRAIDIASRYEGKIQLVSGSDDIALDFMFWGAESWICGPSNCMAKACCDLDRTYKAGDLSKAREMMKTLYRA
MNILESGKFVQKIKYGCELQGLSVGTCRAPLGELTAEEKAEFRAAMEPILNW

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=286, Percent_Identity=26.9230769230769, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI13540533, Length=291, Percent_Identity=26.1168384879725, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788823, Length=286, Percent_Identity=29.7202797202797, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789620, Length=291, Percent_Identity=28.1786941580756, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786463, Length=273, Percent_Identity=28.2051282051282, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87082415, Length=286, Percent_Identity=28.3216783216783, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32453; Mature: 32453

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSGVIPALITPFDANNRIDFKAFEKLLTHLREAGVTGWVPNGSTGEYFSQSREERRDV
CCCCCCCHHHCCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LQFVKEFARPGEILIAGTNAPATREVIEQTALARDIGYDTVLLAPPFYTRPTQAELIRHY
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHH
ESVLGAVDVNLVLYSYPAKDGSDISFELMDHFADNPRVIGIKESSGVLQRAIDIASRYEG
HHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCC
KIQLVSGSDDIALDFMFWGAESWICGPSNCMAKACCDLDRTYKAGDLSKAREMMKTLYRA
EEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
MNILESGKFVQKIKYGCELQGLSVGTCRAPLGELTAEEKAEFRAAMEPILNW
HHHHHCCHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLSGVIPALITPFDANNRIDFKAFEKLLTHLREAGVTGWVPNGSTGEYFSQSREERRDV
CCCCCCCHHHCCCCCCCCEECHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
LQFVKEFARPGEILIAGTNAPATREVIEQTALARDIGYDTVLLAPPFYTRPTQAELIRHY
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHH
ESVLGAVDVNLVLYSYPAKDGSDISFELMDHFADNPRVIGIKESSGVLQRAIDIASRYEG
HHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCC
KIQLVSGSDDIALDFMFWGAESWICGPSNCMAKACCDLDRTYKAGDLSKAREMMKTLYRA
EEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
MNILESGKFVQKIKYGCELQGLSVGTCRAPLGELTAEEKAEFRAAMEPILNW
HHHHHCCHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA