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The map label for this gene is 190894973

Identifier: 190894973

GI number: 190894973

Start: 691945

End: 693003

Strand: Reverse

Name: 190894973

Synonym: RHECIAT_PC0000639

Alternate gene names: NA

Gene position: 693003-691945 (Counterclockwise)

Preceding gene: 190894975

Following gene: 190894972

Centisome position: 63.49

GC content: 60.53

Gene sequence:

>1059_bases
ATGGACATGGGATTCAAAAGAACGATCCACGCGGTTGATACGCACGCGGGCACGCCGATGCGCGTGATAACGGGTGGAAT
TCCGCATATTCCCGGCAATTCCGTCTATGAGAAGATGAAATGGCTGGAGAGCAACGACGACCAGCTGCGCAAGCTGATGC
TGCGCGAGCCGCGCGGCTATCCCGCCCATTGCTGCAACATCATCGTGCCGCCCTGTCACCCGGAAGCCGATGCCGGCTAT
ATCATCCTCGAGCAGGTCGAATATCCGATGATGTCCGGCGGCAATACCATCTCGGTGGTGACGGTGCTTTTGGAAATGGG
CATGCTGCCGATGAAGGAGCCGATCACCGAGCTGGTGCTCGAGGCGCCCGCCGGCCTGATTCGCGTCAAGGCGGAATGCA
GCAACGGCAAGGTCAAGAACGTGACCTTCAAGAACGTCCCGGCATTTGCCGCCCATCTCGATGCCGTCATCGATGTGCCG
CATCTCGGCAGGGTTACCGTCGATGTCGGCTGGGGCGGCATGTTCTATGTCATCGCCGATGTCAGGCAGTTCAAAGGCCT
TGAACTGATCCCGGAACATGGTCGGGAGATCGCGCGCGTTTCCGCGATGATCCGCCAGGCCGCCATCGAACAATTGCCGG
TTGCCCATCCGCATTATCCCGGCGTCGGCATTACAATCTCACAGCTGTCGGGACCGACGGACGATCCGAACGCCGATTGG
AAGAACACGGTGACGATGGCGACAGGCGATCTTTCCTGGGACGACCCAGCCACCTGGACGGGTGCGCTCGATCGCTGCCC
CTGCGGCACCGGCACCTGCGCGAAGATGGCCGTTCTGCATGCGAAGGGCGAATTGCCGCTCCATCAGGCCTTCCGGCATC
AGGGGATTCTCGGCAATATCTACACCGGCAGGCTGGTCGAGGAAGCAAGGATCGGCGACCAATCCGCCGTTGTCCCGACG
CTGAGCGGCACCAGCTGGATCTCGGGCCTGAATACCCTCGTTCTCGACAATGACGACCCCTTCACCGAAGGTTTCACCCT
CGGTGACATCTGGGCTTAA

Upstream 100 bases:

>100_bases
CCACAAACATGACTTTGCTGATTGACAAGTCTGCAGCGTCGTACAAAAGATATCGTATACGATATTACAAAGCAACGACG
TAGGTCGACGTCAGAGGAGA

Downstream 100 bases:

>100_bases
GGAAAGGCGCGCGACGCATCACCTGCGGCGATGATCCCGCTTTCGTTCTGGACGCCATATGTTTACAAGCGGAAGCTGTA
AACATTCGACCGAACGGAGG

Product: putative proline racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MDMGFKRTIHAVDTHAGTPMRVITGGIPHIPGNSVYEKMKWLESNDDQLRKLMLREPRGYPAHCCNIIVPPCHPEADAGY
IILEQVEYPMMSGGNTISVVTVLLEMGMLPMKEPITELVLEAPAGLIRVKAECSNGKVKNVTFKNVPAFAAHLDAVIDVP
HLGRVTVDVGWGGMFYVIADVRQFKGLELIPEHGREIARVSAMIRQAAIEQLPVAHPHYPGVGITISQLSGPTDDPNADW
KNTVTMATGDLSWDDPATWTGALDRCPCGTGTCAKMAVLHAKGELPLHQAFRHQGILGNIYTGRLVEEARIGDQSAVVPT
LSGTSWISGLNTLVLDNDDPFTEGFTLGDIWA

Sequences:

>Translated_352_residues
MDMGFKRTIHAVDTHAGTPMRVITGGIPHIPGNSVYEKMKWLESNDDQLRKLMLREPRGYPAHCCNIIVPPCHPEADAGY
IILEQVEYPMMSGGNTISVVTVLLEMGMLPMKEPITELVLEAPAGLIRVKAECSNGKVKNVTFKNVPAFAAHLDAVIDVP
HLGRVTVDVGWGGMFYVIADVRQFKGLELIPEHGREIARVSAMIRQAAIEQLPVAHPHYPGVGITISQLSGPTDDPNADW
KNTVTMATGDLSWDDPATWTGALDRCPCGTGTCAKMAVLHAKGELPLHQAFRHQGILGNIYTGRLVEEARIGDQSAVVPT
LSGTSWISGLNTLVLDNDDPFTEGFTLGDIWA
>Mature_352_residues
MDMGFKRTIHAVDTHAGTPMRVITGGIPHIPGNSVYEKMKWLESNDDQLRKLMLREPRGYPAHCCNIIVPPCHPEADAGY
IILEQVEYPMMSGGNTISVVTVLLEMGMLPMKEPITELVLEAPAGLIRVKAECSNGKVKNVTFKNVPAFAAHLDAVIDVP
HLGRVTVDVGWGGMFYVIADVRQFKGLELIPEHGREIARVSAMIRQAAIEQLPVAHPHYPGVGITISQLSGPTDDPNADW
KNTVTMATGDLSWDDPATWTGALDRCPCGTGTCAKMAVLHAKGELPLHQAFRHQGILGNIYTGRLVEEARIGDQSAVVPT
LSGTSWISGLNTLVLDNDDPFTEGFTLGDIWA

Specific function: Strong B-cell mitogen. Plays an important role in the regulation of intra- and extracellular amino acid pools, allowing the bacterium to profit from host precursors and enzymatic pathways [H]

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=346, Percent_Identity=28.3236994219653, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: =5.1.1.4 [H]

Molecular weight: Translated: 38244; Mature: 38244

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMGFKRTIHAVDTHAGTPMRVITGGIPHIPGNSVYEKMKWLESNDDQLRKLMLREPRGY
CCCCHHHHEEEHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCC
PAHCCNIIVPPCHPEADAGYIILEQVEYPMMSGGNTISVVTVLLEMGMLPMKEPITELVL
CCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
EAPAGLIRVKAECSNGKVKNVTFKNVPAFAAHLDAVIDVPHLGRVTVDVGWGGMFYVIAD
HCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEHEEH
VRQFKGLELIPEHGREIARVSAMIRQAAIEQLPVAHPHYPGVGITISQLSGPTDDPNADW
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCC
KNTVTMATGDLSWDDPATWTGALDRCPCGTGTCAKMAVLHAKGELPLHQAFRHQGILGNI
CCEEEEEECCCCCCCCCCCCCCHHCCCCCCCHHHHHHEEECCCCCCHHHHHHHCCCEECC
YTGRLVEEARIGDQSAVVPTLSGTSWISGLNTLVLDNDDPFTEGFTLGDIWA
CCCCCHHHHHCCCCCCEEEECCCCHHHCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDMGFKRTIHAVDTHAGTPMRVITGGIPHIPGNSVYEKMKWLESNDDQLRKLMLREPRGY
CCCCHHHHEEEHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCC
PAHCCNIIVPPCHPEADAGYIILEQVEYPMMSGGNTISVVTVLLEMGMLPMKEPITELVL
CCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
EAPAGLIRVKAECSNGKVKNVTFKNVPAFAAHLDAVIDVPHLGRVTVDVGWGGMFYVIAD
HCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEHEEH
VRQFKGLELIPEHGREIARVSAMIRQAAIEQLPVAHPHYPGVGITISQLSGPTDDPNADW
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCC
KNTVTMATGDLSWDDPATWTGALDRCPCGTGTCAKMAVLHAKGELPLHQAFRHQGILGNI
CCEEEEEECCCCCCCCCCCCCCHHCCCCCCCHHHHHHEEECCCCCCHHHHHHHCCCEECC
YTGRLVEEARIGDQSAVVPTLSGTSWISGLNTLVLDNDDPFTEGFTLGDIWA
CCCCCHHHHHCCCCCCEEEECCCCHHHCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA