Click here to switch to the map view.

The map label for this gene is ubiA [H]

Identifier: 190571747

GI number: 190571747

Start: 1472432

End: 1473319

Strand: Reverse

Name: ubiA [H]

Synonym: WPa_1381

Alternate gene names: 190571747

Gene position: 1473319-1472432 (Counterclockwise)

Preceding gene: 190571748

Following gene: 190571746

Centisome position: 99.38

GC content: 34.35

Gene sequence:

>888_bases
ATGTATTTCAACCATTATTTCTCATTAATGAGAATACACAGTTTAACAGGTTTGTGGCTTGTGCTATTTTCTAGCTTAAG
CGGCATTCTTTTAGCCTCAACTTCTCTATCGTATCAGGCTCTTTTTCTCCTTGTTTTGTTTACTATAGGTGCATTTTTAA
TGAGACCCGCAGGGTGCATAATCAATGATATCTTCGATAGAGAAATAGATGCGCACGTTGAACGAACAAAATATAGGCCA
CTTGCAAGTGGTGCATTAAACATAAAGCAGGCTTTGGCTTTACTTTCACTGTTACTGTCTATTGCCCTGGTAATCTTATT
ATTAACCAATAAAACTACTCTTATACTTGGAATAATTTCAATGTGCATGATAGTTATCTACCCCTTGCTAAAGCGTTACG
TTTGGTGGCCACAATTGTTTTTAGGGTTTACTTTCAACATGGGATCACTCATGGGTTCAGCAGCAATAACAAACCAGATT
AGCATAGAATCCTTGCTATTTTATATAGGATGCGTCTTTTGGACGCTTAGTTATGATACTATATACGCTCATCAAGATAA
AAAAGATGATGAGAAATTAGGAATGAAATCTACTGCATTATATTTTGGCAATACAACAAAATCTTGGTTGAAAAGATTTT
ATTTAATATCCTTAATGGCATGGTTGTACGCTGGTATACTATCATCATTAAATAACATCTTTTATATTGCTTTACTTGCC
ATAGGATTCATATTTCACCACCAACACAAAAATTTCAATCCAGACGATTCTAATCAATGCATGTCCATATTTAAAAATAA
TTCCCAGATAGGACTCCTGCTCTTTTTCGGTATCCTTTTAGATAGAATTCTAAATTCTACTTTTGTATCCGTTCAGATGC
ATGGCTAA

Upstream 100 bases:

>100_bases
TGTTGATTTGCGATTTATACCTGAGTTAGTTTTTAAGCCTGATTTAGCATTCGATAATTTTGTCAATGTAAGCAAAATAT
TACATAATCACACTTAATTA

Downstream 100 bases:

>100_bases
TGTGTAAATATCGAAGCAAAAATGGTGTCATTCCAGTGTCAAGTACTGGGATGACAGGGGATGACACCATTTATTTCTAT
GGCTGTCTTTTCTATCTTAT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MYFNHYFSLMRIHSLTGLWLVLFSSLSGILLASTSLSYQALFLLVLFTIGAFLMRPAGCIINDIFDREIDAHVERTKYRP
LASGALNIKQALALLSLLLSIALVILLLTNKTTLILGIISMCMIVIYPLLKRYVWWPQLFLGFTFNMGSLMGSAAITNQI
SIESLLFYIGCVFWTLSYDTIYAHQDKKDDEKLGMKSTALYFGNTTKSWLKRFYLISLMAWLYAGILSSLNNIFYIALLA
IGFIFHHQHKNFNPDDSNQCMSIFKNNSQIGLLLFFGILLDRILNSTFVSVQMHG

Sequences:

>Translated_295_residues
MYFNHYFSLMRIHSLTGLWLVLFSSLSGILLASTSLSYQALFLLVLFTIGAFLMRPAGCIINDIFDREIDAHVERTKYRP
LASGALNIKQALALLSLLLSIALVILLLTNKTTLILGIISMCMIVIYPLLKRYVWWPQLFLGFTFNMGSLMGSAAITNQI
SIESLLFYIGCVFWTLSYDTIYAHQDKKDDEKLGMKSTALYFGNTTKSWLKRFYLISLMAWLYAGILSSLNNIFYIALLA
IGFIFHHQHKNFNPDDSNQCMSIFKNNSQIGLLLFFGILLDRILNSTFVSVQMHG
>Mature_295_residues
MYFNHYFSLMRIHSLTGLWLVLFSSLSGILLASTSLSYQALFLLVLFTIGAFLMRPAGCIINDIFDREIDAHVERTKYRP
LASGALNIKQALALLSLLLSIALVILLLTNKTTLILGIISMCMIVIYPLLKRYVWWPQLFLGFTFNMGSLMGSAAITNQI
SIESLLFYIGCVFWTLSYDTIYAHQDKKDDEKLGMKSTALYFGNTTKSWLKRFYLISLMAWLYAGILSSLNNIFYIALLA
IGFIFHHQHKNFNPDDSNQCMSIFKNNSQIGLLLFFGILLDRILNSTFVSVQMHG

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=40.8602150537634, Blast_Score=206, Evalue=2e-53,
Organism=Escherichia coli, GI1790473, Length=275, Percent_Identity=35.2727272727273, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17553718, Length=287, Percent_Identity=42.1602787456446, Blast_Score=215, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI32565247, Length=283, Percent_Identity=40.9893992932862, Blast_Score=192, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17553720, Length=339, Percent_Identity=35.3982300884956, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI32565245, Length=140, Percent_Identity=45.7142857142857, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32565243, Length=139, Percent_Identity=45.3237410071942, Blast_Score=114, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6324370, Length=287, Percent_Identity=34.4947735191638, Blast_Score=155, Evalue=8e-39,
Organism=Drosophila melanogaster, GI21355567, Length=292, Percent_Identity=40.4109589041096, Blast_Score=218, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 33541; Mature: 33541

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFNHYFSLMRIHSLTGLWLVLFSSLSGILLASTSLSYQALFLLVLFTIGAFLMRPAGCI
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
INDIFDREIDAHVERTKYRPLASGALNIKQALALLSLLLSIALVILLLTNKTTLILGIIS
HHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MCMIVIYPLLKRYVWWPQLFLGFTFNMGSLMGSAAITNQISIESLLFYIGCVFWTLSYDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYAHQDKKDDEKLGMKSTALYFGNTTKSWLKRFYLISLMAWLYAGILSSLNNIFYIALLA
EEECCCCCCHHHHCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFIFHHQHKNFNPDDSNQCMSIFKNNSQIGLLLFFGILLDRILNSTFVSVQMHG
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MYFNHYFSLMRIHSLTGLWLVLFSSLSGILLASTSLSYQALFLLVLFTIGAFLMRPAGCI
CCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
INDIFDREIDAHVERTKYRPLASGALNIKQALALLSLLLSIALVILLLTNKTTLILGIIS
HHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MCMIVIYPLLKRYVWWPQLFLGFTFNMGSLMGSAAITNQISIESLLFYIGCVFWTLSYDT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYAHQDKKDDEKLGMKSTALYFGNTTKSWLKRFYLISLMAWLYAGILSSLNNIFYIALLA
EEECCCCCCHHHHCCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGFIFHHQHKNFNPDDSNQCMSIFKNNSQIGLLLFFGILLDRILNSTFVSVQMHG
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA