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The map label for this gene is tsf

Identifier: 190571620

GI number: 190571620

Start: 1316205

End: 1317050

Strand: Direct

Name: tsf

Synonym: WPa_1244

Alternate gene names: 190571620

Gene position: 1316205-1317050 (Clockwise)

Preceding gene: 190571619

Following gene: 190571621

Centisome position: 88.79

GC content: 34.63

Gene sequence:

>846_bases
ATGAAGATGGATTCAAGTAGTATAAGGGAATTACGCGATAGAACAGGGCTTGGCTTAAGCGATTGTAAGAAAGCGTTAGA
AGAGTGTGATGGTGATATTAAGAAAGCCGTTGATAGGTTACGTACAATAGGATTTGCTAAAGCTGACAAAAAGTCTGATA
GAGTAGCTTCAGATGGGCTTATTGCTATGTGCTTGGCTAAAAATTATGGTGTATTGGTTAAAGTCAATTGTGAAACTGAT
TTTGTTGCTAGAAATGAGAAGTTCATAGCATTAGTTTCAAATTTAGCATCAATTGCTTGTCAAGAACGTTGTACTAGTCT
TGATGAGTTAAAAAATGCCAAATATGAAGATGTTGGTACAGTACAGGAAGCTATTATAAGTGGTACATCGGTTCTTGGTG
AGAAGTTAGAGTTAAGCAATCTTTGCTACCTAGAGACTAAGGATGGGATTATTGCTGGCTATGTACATGGTGATATGCAT
GGCTTAGGTAAGATTGGTGCTTTAGTAGCATTGCAATCATCTGGTGATAAACAAGAGATTGGAAAGCAAATAGCTATGCA
TGTAGTTGCTATGAAACCTGAAGCTTTATCTATAGATGATTTAGATCAAGAAAAATTAAACAATGAGCGTTCTATAATTG
AGGAGCAAGTAAAGAGCTTAAATAAACCTGAAGAGGTAGCGAAAAAAATAGTAGATGGACGAATGGCTAAATACTATGAA
GAAGTTGTTCTACTAGAGCAGAAGTTTATAAAAGATGATAAAATGAAGATTGCTGATTTTATAGAATCAAGTGCTGTTAA
ATTAGCTAATTATAAGTTACTTACTTTGGATGGTGCAAATAAGTAA

Upstream 100 bases:

>100_bases
TTAAGGATGATGAGCTTATTCAAGAAAAAGAAGGGGGTATTGTGCAAACTAAAAAGAAGCGTATGAAGGATGAAACAGAA
AGGGAGGTAATAGTAAGTAA

Downstream 100 bases:

>100_bases
CAAAACTTCAGAAGTAAAGTACCCCAGAGTGTTATTCAAAATCTCTGGGGAGGCTTTGATGGGATCAAAGCTATTTGGCC
ATGATATGGAAGTTATAGAT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKMDSSSIRELRDRTGLGLSDCKKALEECDGDIKKAVDRLRTIGFAKADKKSDRVASDGLIAMCLAKNYGVLVKVNCETD
FVARNEKFIALVSNLASIACQERCTSLDELKNAKYEDVGTVQEAIISGTSVLGEKLELSNLCYLETKDGIIAGYVHGDMH
GLGKIGALVALQSSGDKQEIGKQIAMHVVAMKPEALSIDDLDQEKLNNERSIIEEQVKSLNKPEEVAKKIVDGRMAKYYE
EVVLLEQKFIKDDKMKIADFIESSAVKLANYKLLTLDGANK

Sequences:

>Translated_281_residues
MKMDSSSIRELRDRTGLGLSDCKKALEECDGDIKKAVDRLRTIGFAKADKKSDRVASDGLIAMCLAKNYGVLVKVNCETD
FVARNEKFIALVSNLASIACQERCTSLDELKNAKYEDVGTVQEAIISGTSVLGEKLELSNLCYLETKDGIIAGYVHGDMH
GLGKIGALVALQSSGDKQEIGKQIAMHVVAMKPEALSIDDLDQEKLNNERSIIEEQVKSLNKPEEVAKKIVDGRMAKYYE
EVVLLEQKFIKDDKMKIADFIESSAVKLANYKLLTLDGANK
>Mature_281_residues
MKMDSSSIRELRDRTGLGLSDCKKALEECDGDIKKAVDRLRTIGFAKADKKSDRVASDGLIAMCLAKNYGVLVKVNCETD
FVARNEKFIALVSNLASIACQERCTSLDELKNAKYEDVGTVQEAIISGTSVLGEKLELSNLCYLETKDGIIAGYVHGDMH
GLGKIGALVALQSSGDKQEIGKQIAMHVVAMKPEALSIDDLDQEKLNNERSIIEEQVKSLNKPEEVAKKIVDGRMAKYYE
EVVLLEQKFIKDDKMKIADFIESSAVKLANYKLLTLDGANK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=285, Percent_Identity=30.1754385964912, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI291084500, Length=307, Percent_Identity=29.3159609120521, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI291084502, Length=110, Percent_Identity=41.8181818181818, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI291084498, Length=110, Percent_Identity=41.8181818181818, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786366, Length=270, Percent_Identity=34.0740740740741, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17561440, Length=295, Percent_Identity=24.406779661017, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921466, Length=246, Percent_Identity=30.8943089430894, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_WOLPP (B3CNH0)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975978.1
- EnsemblBacteria:   EBWOLT00000000194
- GeneID:   6385671
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_1244
- GeneTree:   EBGT00050000030835
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 30928; Mature: 30928

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMDSSSIRELRDRTGLGLSDCKKALEECDGDIKKAVDRLRTIGFAKADKKSDRVASDGL
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHCCCCCCHHHCCCH
IAMCLAKNYGVLVKVNCETDFVARNEKFIALVSNLASIACQERCTSLDELKNAKYEDVGT
HEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHH
VQEAIISGTSVLGEKLELSNLCYLETKDGIIAGYVHGDMHGLGKIGALVALQSSGDKQEI
HHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCHHHHHHHHHHEEECCCCCHHHH
GKQIAMHVVAMKPEALSIDDLDQEKLNNERSIIEEQVKSLNKPEEVAKKIVDGRMAKYYE
HHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EVVLLEQKFIKDDKMKIADFIESSAVKLANYKLLTLDGANK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEEECCCCC
>Mature Secondary Structure
MKMDSSSIRELRDRTGLGLSDCKKALEECDGDIKKAVDRLRTIGFAKADKKSDRVASDGL
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHCCCCCCHHHCCCH
IAMCLAKNYGVLVKVNCETDFVARNEKFIALVSNLASIACQERCTSLDELKNAKYEDVGT
HEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHH
VQEAIISGTSVLGEKLELSNLCYLETKDGIIAGYVHGDMHGLGKIGALVALQSSGDKQEI
HHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCHHHHHHHHHHEEECCCCCHHHH
GKQIAMHVVAMKPEALSIDDLDQEKLNNERSIIEEQVKSLNKPEEVAKKIVDGRMAKYYE
HHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EVVLLEQKFIKDDKMKIADFIESSAVKLANYKLLTLDGANK
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA