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The map label for this gene is pyrH [H]

Identifier: 190571621

GI number: 190571621

Start: 1317034

End: 1317777

Strand: Direct

Name: pyrH [H]

Synonym: WPa_1245

Alternate gene names: 190571621

Gene position: 1317034-1317777 (Clockwise)

Preceding gene: 190571620

Following gene: 190571622

Centisome position: 88.84

GC content: 34.81

Gene sequence:

>744_bases
ATGGTGCAAATAAGTAACAAAACTTCAGAAGTAAAGTACCCCAGAGTGTTATTCAAAATCTCTGGGGAGGCTTTGATGGG
ATCAAAGCTATTTGGCCATGATATGGAAGTTATAGATAAACTATCCAAAGACATAGTTGAAGTTTGTAATCTTGGAGTTC
AAGTTTGTATTGTTGTTGGTGGTGGGAATATTTTTCGTGGTGCATCAGCATCTTTAAGTGGCTGTGAAAGAGCAAGCAGT
GATTATATTGGAATGCTTGGTACTGTCATTAATGCTTTAATTTTGCAAAATTTTTTAGAAAAAAGCTCTATAGTCTCTAG
GGTGTTGTCTGCTATACCTATGACTACTATATGTGAACCTTATATAAGAAGGAAGGCTATTCATCATTTAGAGAAAGGTA
GAGTAGTCATTTTTGCAGCAGGCACAGGTAACCCATTTTTTACTACGGATACAGCTGCAGCTTTACGTGCTGTTGAAATG
AATTGTGATGTTATTTTAAAAGGTACTCAAGTAAGTGGTGTATATTCTGCCGATCCAAAAAAAAATGAGAATGCTGTGAT
GTATGATAGGCTTTCTTATACAGATCTGCTAACTCGTGATTTAAAAGTTATGGATGCATCAGCAATTTCACTTGCTCGTG
AGAATTCTATCCCAATTGTAGTTTTTTCTTTAAAAAGAGAAAAAATGGTTGATATTATTAAGGGTCAAGGCACTTATACT
ATAGTTTCAGATTGTAAACATTAG

Upstream 100 bases:

>100_bases
CTACTAGAGCAGAAGTTTATAAAAGATGATAAAATGAAGATTGCTGATTTTATAGAATCAAGTGCTGTTAAATTAGCTAA
TTATAAGTTACTTACTTTGG

Downstream 100 bases:

>100_bases
GTAATTTATGTTAAACGAAATAAAAGCTAAAACAAAAGAAAGAATGCTAAAAACTATTCAGTCTTTTCACGATGATATGA
AAGGTGTACGTACTGGTAGA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MVQISNKTSEVKYPRVLFKISGEALMGSKLFGHDMEVIDKLSKDIVEVCNLGVQVCIVVGGGNIFRGASASLSGCERASS
DYIGMLGTVINALILQNFLEKSSIVSRVLSAIPMTTICEPYIRRKAIHHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEM
NCDVILKGTQVSGVYSADPKKNENAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIVVFSLKREKMVDIIKGQGTYT
IVSDCKH

Sequences:

>Translated_247_residues
MVQISNKTSEVKYPRVLFKISGEALMGSKLFGHDMEVIDKLSKDIVEVCNLGVQVCIVVGGGNIFRGASASLSGCERASS
DYIGMLGTVINALILQNFLEKSSIVSRVLSAIPMTTICEPYIRRKAIHHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEM
NCDVILKGTQVSGVYSADPKKNENAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIVVFSLKREKMVDIIKGQGTYT
IVSDCKH
>Mature_247_residues
MVQISNKTSEVKYPRVLFKISGEALMGSKLFGHDMEVIDKLSKDIVEVCNLGVQVCIVVGGGNIFRGASASLSGCERASS
DYIGMLGTVINALILQNFLEKSSIVSRVLSAIPMTTICEPYIRRKAIHHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEM
NCDVILKGTQVSGVYSADPKKNENAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIVVFSLKREKMVDIIKGQGTYT
IVSDCKH

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=233, Percent_Identity=44.206008583691, Blast_Score=231, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26917; Mature: 26917

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQISNKTSEVKYPRVLFKISGEALMGSKLFGHDMEVIDKLSKDIVEVCNLGVQVCIVVG
CEEECCCCCCCCCCEEEEEECCCHHCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
GGNIFRGASASLSGCERASSDYIGMLGTVINALILQNFLEKSSIVSRVLSAIPMTTICEP
CCCEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YIRRKAIHHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEMNCDVILKGTQVSGVYSADPK
HHHHHHHHHHCCCCEEEEEECCCCCCEECCHHHHHHHEECCCCEEEECCEECCEEECCCC
KNENAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIVVFSLKREKMVDIIKGQGTYT
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCEE
IVSDCKH
EECCCCC
>Mature Secondary Structure
MVQISNKTSEVKYPRVLFKISGEALMGSKLFGHDMEVIDKLSKDIVEVCNLGVQVCIVVG
CEEECCCCCCCCCCEEEEEECCCHHCCCHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEE
GGNIFRGASASLSGCERASSDYIGMLGTVINALILQNFLEKSSIVSRVLSAIPMTTICEP
CCCEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
YIRRKAIHHLEKGRVVIFAAGTGNPFFTTDTAAALRAVEMNCDVILKGTQVSGVYSADPK
HHHHHHHHHHCCCCEEEEEECCCCCCEECCHHHHHHHEECCCCEEEECCEECCEEECCCC
KNENAVMYDRLSYTDLLTRDLKVMDASAISLARENSIPIVVFSLKREKMVDIIKGQGTYT
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCEE
IVSDCKH
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA