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The map label for this gene is nuoH [H]

Identifier: 190571481

GI number: 190571481

Start: 1169866

End: 1170891

Strand: Direct

Name: nuoH [H]

Synonym: WPa_1096

Alternate gene names: 190571481

Gene position: 1169866-1170891 (Clockwise)

Preceding gene: 190571480

Following gene: 190571482

Centisome position: 78.91

GC content: 36.35

Gene sequence:

>1026_bases
ATGTACTTGATATTTGATATTCTTTTTCTTCTTATTCCACTTTTGCTTTCAGTAGCATATTTAGTGTACTTTGAGCGTAA
AGTTATTGGTGCAATTCAACTAAGGCATGGTCCAAGTGTAGTAGGGCCATTTGGGCTACTACAGCCATTTGCAGATGCTA
TCAAATTGATAATTAAAGAGCCGATAATACCATTTAGAGCAAACACCATACTGTTTATTATGGCTCCAATGCTCACCTTT
ATTTTAGCATTAATTTCCTGGGCAGTTATACCATTTGGAGCTGAAATAATTACAGAAAATGGACAGCAGGTAATAATCCC
TAAGGTAATAGCAAATATTAATGTTGGAGTGCTTTATGTGCTAGCTATATCCTCTTTGGGAATATATGGCATTATTATTG
CAGGCTGGTCTAGTAATTCTAATTATGCATTTCTTGGCGCTATAAGGTCAGCTGCTCAAATGATTTCATATGAAGTTTCA
ATAGGTCTAATAGTTGCTACAGTTGTTATTACAACTGGTACGTTGAATCTTGCAGAGATGGTGGTAGCGAAACATAATAT
GCCATTTTGGATTGATTTGCTGATGATGCCTATAGGAATAATATTTTTTATTTCTTTGCTTGCAGAAACTAACCGTCACC
CATTTGACTTACCAGAAGCTGAAGCAGAGCTTGTCTCTGGGTATAACGTCGAATATTCATCAATGCCTTTTGCTCTCTTT
TTTCTAGGAGAGTATGCAAATATGATTTTAGCAAGCGCTGTGATGACAATATTCTTTCTAGGAGGGTGGTATCCTCCACT
AGAGCTTAGTTTACTATATAAAATTCCAGGTTTGATTTGGTTCGTTTTGAAGATAGTTTTATTATTGTTCATATTTATTT
GGATCAGGGCAACAATACCCCGTTACAGATATGACCAACTAATGCGTCTTGGTTGGAAAGTGTTTCTACCGATATCAGTG
CTTTGGGTAATACTCATTTCAGGAGTGTTGCTTTTTACTGGGAACTTGCCTGGGTCCAATGTTTAA

Upstream 100 bases:

>100_bases
GTCCTATTGATTTCAATAGGGACATTGTCTTGTGTGTCTAGAGCATTTGCTGTATTTTTTATTGCCACAATTATGAACTA
TTTTTTTGATTTAGGGTTGC

Downstream 100 bases:

>100_bases
CTTTCCAAACATAAGATTAAGACGCAGGCGCTCAGGCAAGTGGATTCGCAATTTAACAAGTGAAATCACTTTATCAGTAA
ATGATTTGATTTTTCCCTTA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MYLIFDILFLLIPLLLSVAYLVYFERKVIGAIQLRHGPSVVGPFGLLQPFADAIKLIIKEPIIPFRANTILFIMAPMLTF
ILALISWAVIPFGAEIITENGQQVIIPKVIANINVGVLYVLAISSLGIYGIIIAGWSSNSNYAFLGAIRSAAQMISYEVS
IGLIVATVVITTGTLNLAEMVVAKHNMPFWIDLLMMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
FLGEYANMILASAVMTIFFLGGWYPPLELSLLYKIPGLIWFVLKIVLLLFIFIWIRATIPRYRYDQLMRLGWKVFLPISV
LWVILISGVLLFTGNLPGSNV

Sequences:

>Translated_341_residues
MYLIFDILFLLIPLLLSVAYLVYFERKVIGAIQLRHGPSVVGPFGLLQPFADAIKLIIKEPIIPFRANTILFIMAPMLTF
ILALISWAVIPFGAEIITENGQQVIIPKVIANINVGVLYVLAISSLGIYGIIIAGWSSNSNYAFLGAIRSAAQMISYEVS
IGLIVATVVITTGTLNLAEMVVAKHNMPFWIDLLMMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
FLGEYANMILASAVMTIFFLGGWYPPLELSLLYKIPGLIWFVLKIVLLLFIFIWIRATIPRYRYDQLMRLGWKVFLPISV
LWVILISGVLLFTGNLPGSNV
>Mature_341_residues
MYLIFDILFLLIPLLLSVAYLVYFERKVIGAIQLRHGPSVVGPFGLLQPFADAIKLIIKEPIIPFRANTILFIMAPMLTF
ILALISWAVIPFGAEIITENGQQVIIPKVIANINVGVLYVLAISSLGIYGIIIAGWSSNSNYAFLGAIRSAAQMISYEVS
IGLIVATVVITTGTLNLAEMVVAKHNMPFWIDLLMMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
FLGEYANMILASAVMTIFFLGGWYPPLELSLLYKIPGLIWFVLKIVLLLFIFIWIRATIPRYRYDQLMRLGWKVFLPISV
LWVILISGVLLFTGNLPGSNV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=304, Percent_Identity=45.3947368421053, Blast_Score=267, Evalue=1e-71,
Organism=Escherichia coli, GI1788618, Length=318, Percent_Identity=39.3081761006289, Blast_Score=238, Evalue=5e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38042; Mature: 38042

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLIFDILFLLIPLLLSVAYLVYFERKVIGAIQLRHGPSVVGPFGLLQPFADAIKLIIKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHC
PIIPFRANTILFIMAPMLTFILALISWAVIPFGAEIITENGQQVIIPKVIANINVGVLYV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCEEEHHHHHHCCCHHHHHH
LAISSLGIYGIIIAGWSSNSNYAFLGAIRSAAQMISYEVSIGLIVATVVITTGTLNLAEM
HHHHHCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VVAKHNMPFWIDLLMMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEECCCCHHHH
FLGEYANMILASAVMTIFFLGGWYPPLELSLLYKIPGLIWFVLKIVLLLFIFIWIRATIP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RYRYDQLMRLGWKVFLPISVLWVILISGVLLFTGNLPGSNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MYLIFDILFLLIPLLLSVAYLVYFERKVIGAIQLRHGPSVVGPFGLLQPFADAIKLIIKE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHC
PIIPFRANTILFIMAPMLTFILALISWAVIPFGAEIITENGQQVIIPKVIANINVGVLYV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCEEEHHHHHHCCCHHHHHH
LAISSLGIYGIIIAGWSSNSNYAFLGAIRSAAQMISYEVSIGLIVATVVITTGTLNLAEM
HHHHHCCEEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VVAKHNMPFWIDLLMMPIGIIFFISLLAETNRHPFDLPEAEAELVSGYNVEYSSMPFALF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEECCCCHHHH
FLGEYANMILASAVMTIFFLGGWYPPLELSLLYKIPGLIWFVLKIVLLLFIFIWIRATIP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RYRYDQLMRLGWKVFLPISVLWVILISGVLLFTGNLPGSNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA