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The map label for this gene is hflK [H]

Identifier: 190571441

GI number: 190571441

Start: 1124383

End: 1125408

Strand: Reverse

Name: hflK [H]

Synonym: WPa_1054

Alternate gene names: 190571441

Gene position: 1125408-1124383 (Counterclockwise)

Preceding gene: 190571442

Following gene: 190571440

Centisome position: 75.92

GC content: 34.21

Gene sequence:

>1026_bases
ATGGATGAGCGTAATCCTTGGAATCTTGGAAAGAAACCGTCAGGTTCAAGTAATGAAGATATTTTAAGTAAAGCTGTGTC
TGATATAAGATGCTTTTTTAATGGCTTAACCAGAAATAGAGGGAAAAAACCTTATTTCATCATTTTTATTGTTTTGTTGT
TTTATCTTTGTACTGGTTTCTATATTGTCCATCCGAGTGAGGAAGGTATAGAACTTACTTTTGGCAAATATTCCAATACA
GAAACATCTGGTTTGCGTTATCACTTTCCCTACCCTATTGGTAAGGTTTTTAAAGTGAATGTTAAAGAAGTAAATCGTGA
AGAAATTGGGATAAGCAGCTCTTATGGGCGAGATACAGATCGTGGTGAAGGAGTGATGCTTACCGGAGATGAGAATATAG
TCAACGTTAACTTTGAGGTCCAGTGGCGAGTTAGAGATGCCAAAGATTATTTATTCAAAGTGCGGGATTATAAACCTGGT
TTCAGCGTTAAAAATGCTGCTGAAAGTGCTATGAGAGAAATAATAGGTAAAAATACGATCTCTTTTGCACTCGAAGGTCA
AGGTAGGGCTGAAATCTCCAGAGATACTAGAATTTTATTGCAACAGATTCTTGATGGATATCAAATGGGTATAGAAATTT
TATCTGTTCAAATGAAAAAAATTGACCCACCAGAAAAAGTGATTAGCTCATTTAGGGATGTACAAAGTGCTCGTGCAGAT
AAGGAGCGTACTATAAACGAAGCATATGCTTACAGTAATGATATTATACCTCGTGCAAAAGGTGAAGCAATAAAGATAAA
ATTAGATGCAGAAGCATATGAGAACGAAATAATAAATGAAGCGAAAGGTAATGCAAATCGCTTTTTATCTCTTTATGAAG
AATATAGACAAAATCCTTCTCTTGTTAAGAATCGTATTTATCTTGAAACTATGGAAAATATTTTTAGCAAGGTAGATAAA
TTTGTTATAACAGACGATCTGAAAGGTATGTTCTCTTATTTACCTCTTACAAATCTAGGAAAATAG

Upstream 100 bases:

>100_bases
CATCCTTCACTCCGATCATTAATCTGCAAACAAAATAGTTTTGCATTTTTTGATAAGATTAAGTAATATCATCGTATTAG
TTATACAATTAATAATTTTT

Downstream 100 bases:

>100_bases
TCATGAGTAGTAATATTAAAATTGTTTTTGCTTTTGTATTTGTTGCATTATTGATTGCATTATCTAATTCAATCTTTGTT
GTTCAAGAAACAAAACAAGC

Product: hflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MDERNPWNLGKKPSGSSNEDILSKAVSDIRCFFNGLTRNRGKKPYFIIFIVLLFYLCTGFYIVHPSEEGIELTFGKYSNT
ETSGLRYHFPYPIGKVFKVNVKEVNREEIGISSSYGRDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRDYKPG
FSVKNAAESAMREIIGKNTISFALEGQGRAEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSARAD
KERTINEAYAYSNDIIPRAKGEAIKIKLDAEAYENEIINEAKGNANRFLSLYEEYRQNPSLVKNRIYLETMENIFSKVDK
FVITDDLKGMFSYLPLTNLGK

Sequences:

>Translated_341_residues
MDERNPWNLGKKPSGSSNEDILSKAVSDIRCFFNGLTRNRGKKPYFIIFIVLLFYLCTGFYIVHPSEEGIELTFGKYSNT
ETSGLRYHFPYPIGKVFKVNVKEVNREEIGISSSYGRDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRDYKPG
FSVKNAAESAMREIIGKNTISFALEGQGRAEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSARAD
KERTINEAYAYSNDIIPRAKGEAIKIKLDAEAYENEIINEAKGNANRFLSLYEEYRQNPSLVKNRIYLETMENIFSKVDK
FVITDDLKGMFSYLPLTNLGK
>Mature_341_residues
MDERNPWNLGKKPSGSSNEDILSKAVSDIRCFFNGLTRNRGKKPYFIIFIVLLFYLCTGFYIVHPSEEGIELTFGKYSNT
ETSGLRYHFPYPIGKVFKVNVKEVNREEIGISSSYGRDTDRGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRDYKPG
FSVKNAAESAMREIIGKNTISFALEGQGRAEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSARAD
KERTINEAYAYSNDIIPRAKGEAIKIKLDAEAYENEIINEAKGNANRFLSLYEEYRQNPSLVKNRIYLETMENIFSKVDK
FVITDDLKGMFSYLPLTNLGK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=282, Percent_Identity=37.5886524822695, Blast_Score=173, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 39044; Mature: 39044

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERNPWNLGKKPSGSSNEDILSKAVSDIRCFFNGLTRNRGKKPYFIIFIVLLFYLCTGF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCE
YIVHPSEEGIELTFGKYSNTETSGLRYHFPYPIGKVFKVNVKEVNREEIGISSSYGRDTD
EEECCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEEHHHCCHHHCCCCCCCCCCCC
RGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRDYKPGFSVKNAAESAMREIIGKNTI
CCCEEEEECCCCEEEEEEEEEEEEECCHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCE
SFALEGQGRAEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSARAD
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KERTINEAYAYSNDIIPRAKGEAIKIKLDAEAYENEIINEAKGNANRFLSLYEEYRQNPS
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
LVKNRIYLETMENIFSKVDKFVITDDLKGMFSYLPLTNLGK
HHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDERNPWNLGKKPSGSSNEDILSKAVSDIRCFFNGLTRNRGKKPYFIIFIVLLFYLCTGF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCE
YIVHPSEEGIELTFGKYSNTETSGLRYHFPYPIGKVFKVNVKEVNREEIGISSSYGRDTD
EEECCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEEEEHHHCCHHHCCCCCCCCCCCC
RGEGVMLTGDENIVNVNFEVQWRVRDAKDYLFKVRDYKPGFSVKNAAESAMREIIGKNTI
CCCEEEEECCCCEEEEEEEEEEEEECCHHHHEEEECCCCCCCHHHHHHHHHHHHHCCCCE
SFALEGQGRAEISRDTRILLQQILDGYQMGIEILSVQMKKIDPPEKVISSFRDVQSARAD
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
KERTINEAYAYSNDIIPRAKGEAIKIKLDAEAYENEIINEAKGNANRFLSLYEEYRQNPS
HHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCCHH
LVKNRIYLETMENIFSKVDKFVITDDLKGMFSYLPLTNLGK
HHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]