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The map label for this gene is hflC [H]

Identifier: 190571440

GI number: 190571440

Start: 1123508

End: 1124380

Strand: Reverse

Name: hflC [H]

Synonym: WPa_1053

Alternate gene names: 190571440

Gene position: 1124380-1123508 (Counterclockwise)

Preceding gene: 190571441

Following gene: 190571439

Centisome position: 75.85

GC content: 31.39

Gene sequence:

>873_bases
ATGAGTAGTAATATTAAAATTGTTTTTGCTTTTGTATTTGTTGCATTATTGATTGCATTATCTAATTCAATCTTTGTTGT
TCAAGAAACAAAACAAGCAATAGTTATACAACTCGGTAAAGTCGTAAAAGATGTTAGGGACAGTGGTTTATATTTTAAAT
TGCCATTTATAAATAACGTAGAATTTCTTGATAAGAGAATTTTAGATCTAAGTCCTGATAAAACTCCAAGGGAAGTGATA
ACTGCAGATCAAAAGCGTATTATAGTAGATGCTTATGCAAAATATAAAATAATAGATCCTATCACTTTTTATCAGACTGT
GAAAAATGAATCAGGGCTAGTTAGAAGATTATATCCTGTCATAGAAGCTCACATAAGGGAGAATATAGGAAGATTTTCAT
TAATTAGTTTATTGAATGAAAAGAGATCAGAAGTTATGCAATTAATTCAACGTGGAGTTTATTCTGAAGCTGGAAAATTT
GGCATAGAGATAATAGATGTAAGAATTAAGAGAGCAGATCTACCAGAAGAAAATAGTTCTGCAATATTCCGCCGCATGCA
AACTGAAAGAGAAAAGGAAGCAAAAGAAATTAGAGCAGAAGGAGAACAAGCTGGACAAGAAATTAGATCAAAAGCTGATA
AATTAAAAAGGGGGATTGTCTCTAGTGCAGTAAAAGAATCACATGAAATAAGAGGCCGTGGTTATGCTGAAGCAACTAGA
ATCTATAATGAGGCATTCAAGGTTGATGAAGAGTTTTTTAACTTTTATCGCTCTATGAAAGCTTACAGTAAATCATTTGC
TGAGGGTAATACTAAATTTGTGCTTTCACCAAATAATAATTTCTTAGATATTTTGAACAAGGGATGGAAATAG

Upstream 100 bases:

>100_bases
CTATGGAAAATATTTTTAGCAAGGTAGATAAATTTGTTATAACAGACGATCTGAAAGGTATGTTCTCTTATTTACCTCTT
ACAAATCTAGGAAAATAGTC

Downstream 100 bases:

>100_bases
TTTATGAAAAGTAAAGCATTTATTTTATCTATATTTGCATATTTTTTAATTTCATTTGCTTCATATGCTAATCTGTTTGC
AAAAACAGTTGCAGATCCTG

Product: hflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSSNIKIVFAFVFVALLIALSNSIFVVQETKQAIVIQLGKVVKDVRDSGLYFKLPFINNVEFLDKRILDLSPDKTPREVI
TADQKRIIVDAYAKYKIIDPITFYQTVKNESGLVRRLYPVIEAHIRENIGRFSLISLLNEKRSEVMQLIQRGVYSEAGKF
GIEIIDVRIKRADLPEENSSAIFRRMQTEREKEAKEIRAEGEQAGQEIRSKADKLKRGIVSSAVKESHEIRGRGYAEATR
IYNEAFKVDEEFFNFYRSMKAYSKSFAEGNTKFVLSPNNNFLDILNKGWK

Sequences:

>Translated_290_residues
MSSNIKIVFAFVFVALLIALSNSIFVVQETKQAIVIQLGKVVKDVRDSGLYFKLPFINNVEFLDKRILDLSPDKTPREVI
TADQKRIIVDAYAKYKIIDPITFYQTVKNESGLVRRLYPVIEAHIRENIGRFSLISLLNEKRSEVMQLIQRGVYSEAGKF
GIEIIDVRIKRADLPEENSSAIFRRMQTEREKEAKEIRAEGEQAGQEIRSKADKLKRGIVSSAVKESHEIRGRGYAEATR
IYNEAFKVDEEFFNFYRSMKAYSKSFAEGNTKFVLSPNNNFLDILNKGWK
>Mature_289_residues
SSNIKIVFAFVFVALLIALSNSIFVVQETKQAIVIQLGKVVKDVRDSGLYFKLPFINNVEFLDKRILDLSPDKTPREVIT
ADQKRIIVDAYAKYKIIDPITFYQTVKNESGLVRRLYPVIEAHIRENIGRFSLISLLNEKRSEVMQLIQRGVYSEAGKFG
IEIIDVRIKRADLPEENSSAIFRRMQTEREKEAKEIRAEGEQAGQEIRSKADKLKRGIVSSAVKESHEIRGRGYAEATRI
YNEAFKVDEEFFNFYRSMKAYSKSFAEGNTKFVLSPNNNFLDILNKGWK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=310, Percent_Identity=30.6451612903226, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17569497, Length=218, Percent_Identity=29.3577981651376, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17569493, Length=198, Percent_Identity=26.2626262626263, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193209764, Length=198, Percent_Identity=26.2626262626263, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281361633, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281361631, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 33347; Mature: 33216

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNIKIVFAFVFVALLIALSNSIFVVQETKQAIVIQLGKVVKDVRDSGLYFKLPFINNV
CCCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
EFLDKRILDLSPDKTPREVITADQKRIIVDAYAKYKIIDPITFYQTVKNESGLVRRLYPV
HHHHHHHHCCCCCCCCHHHHCCCCCEEEEEHHHCEEEECHHHHHHHHCCCCHHHHHHHHH
IEAHIRENIGRFSLISLLNEKRSEVMQLIQRGVYSEAGKFGIEIIDVRIKRADLPEENSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHH
AIFRRMQTEREKEAKEIRAEGEQAGQEIRSKADKLKRGIVSSAVKESHEIRGRGYAEATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IYNEAFKVDEEFFNFYRSMKAYSKSFAEGNTKFVLSPNNNFLDILNKGWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCC
>Mature Secondary Structure 
SSNIKIVFAFVFVALLIALSNSIFVVQETKQAIVIQLGKVVKDVRDSGLYFKLPFINNV
CCCHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
EFLDKRILDLSPDKTPREVITADQKRIIVDAYAKYKIIDPITFYQTVKNESGLVRRLYPV
HHHHHHHHCCCCCCCCHHHHCCCCCEEEEEHHHCEEEECHHHHHHHHCCCCHHHHHHHHH
IEAHIRENIGRFSLISLLNEKRSEVMQLIQRGVYSEAGKFGIEIIDVRIKRADLPEENSS
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCHH
AIFRRMQTEREKEAKEIRAEGEQAGQEIRSKADKLKRGIVSSAVKESHEIRGRGYAEATR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IYNEAFKVDEEFFNFYRSMKAYSKSFAEGNTKFVLSPNNNFLDILNKGWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]