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The map label for this gene is ffh [H]

Identifier: 190571419

GI number: 190571419

Start: 1096403

End: 1097746

Strand: Reverse

Name: ffh [H]

Synonym: WPa_1032

Alternate gene names: 190571419

Gene position: 1097746-1096403 (Counterclockwise)

Preceding gene: 190571420

Following gene: 190571418

Centisome position: 74.05

GC content: 36.24

Gene sequence:

>1344_bases
ATGTTTAAATCGTTAACCGAAAGTTTAAATTCTGTATTTAGTAAACTGAGAGGAAAGTCAATCATTTCTGAAGATGATTT
TAACCTTGCCATGCGTGAAATACGTATAGCTTTAATTGAAGCTGACGTTTCACTTGAAGTTGCGAAAAAATTCATCAATG
ACATTAAAGATAAAGTGATTGGGGAAAAAGTCATAAAAAGCGTTTCTCCATCGCAAATGATAATCAAAATTGTGCAGGAT
AATTTAGTTGCAGTTCTCGGATCAGAGAAAAGCGACTTAAACCTAGCAGCTAAACCCCCTGCTGTGATTATGATGGTGGG
CCTACAAGGTGCGGGTAAAACAACCACCTCAGGGAAGCTTGCTTTAAAGTTAAAAAAACAAAAGAAAAAAGTGATGCTCG
CTTCTTTAGACATTTATAGACCGGCTGCCCAAAAACAACTTGAAGTGCTAGGTAAACAAATAGATGTGCAAACTTTACCT
GTAGTAATAGACGAGAAGCCCGTTACAATTACAAAAAGGGCACTGGCAGCAGCAAAGAACGAAAATTATGATGTATTAAT
ACTAGACACCGCAGGCAGGCTTCATATTGATAATAATATGATGAATGAGTTGAAAGCCGTAAAGGAAATAGCTTCACCTG
CAGAAGTTATTTTAGTAGCCGACGCAATGATAGGCCAGGATTCGGTCAATATTGCCAAATCATTCAATGAGATAATAGGT
GTAACCGGCATTATTCTCACCCGTGTTGATGGTGATGCACGTGGTGGTGCTGCTCTTTCTATGAAAATGATCACCGATTG
TCCAATTAAATTTATTGCTTGTGGTGAAAAATTAAGTGATCTCGATGATTTTTATCCCGATAGAATTGCAAAAAGGATAC
TTAGCATGGGTGATGTTGTATCATTGGTTGAAAAAGCTGCTGAGATTGTTGGTCAGGAAGAAATTGATAAGTTACAAAAG
AAAGTAAAAAAGGGTAAATTCGACCTAAACGACCTAGTGGGAATGTTAAAGACTCTGAGTAAAATGGATGGCATTAGCAA
CATAATGAAATTCATTCCTAGTTCATTCACAAAAAAGCTAAGTAGCAGTGTGCCCGATGACAATAAAGTGAAAAAATATA
TAGCCATCATAAACTCAATGACCGAAAAAGAAAGGCAAAATCCAGATATTTTAAATGGCAAAAGAAGACTTAGAATTTCT
AAGGGGTCCGGAACAAGTGTAACTGACGTTAATCTTCTAATTAAGCAGTATAATCAAATGAGCTCTATGGTGAATAAGTT
CAGTAAAATTGACCATAGTAAACTCAAAGAATCTGATTTGATGGATATGCTAAGCAGAAAGTAA

Upstream 100 bases:

>100_bases
TTAATAATATTACTAAACTTAAAGAAGTGCTGAGTTATAACTCAGTGAGTTTTGTTTCAGCTTCTTCTCTCTTTTTAATG
AGTATTCTACTAGCGCTATT

Downstream 100 bases:

>100_bases
GTCAGCAGGTAGTGGAATGAAATAAAATCATCAGTTGTAATTGCTGTTGAATAGTAAAGTATATTATTTTAGCGTGAAGT
AATAAATTCAATAAATTTCT

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MFKSLTESLNSVFSKLRGKSIISEDDFNLAMREIRIALIEADVSLEVAKKFINDIKDKVIGEKVIKSVSPSQMIIKIVQD
NLVAVLGSEKSDLNLAAKPPAVIMMVGLQGAGKTTTSGKLALKLKKQKKKVMLASLDIYRPAAQKQLEVLGKQIDVQTLP
VVIDEKPVTITKRALAAAKNENYDVLILDTAGRLHIDNNMMNELKAVKEIASPAEVILVADAMIGQDSVNIAKSFNEIIG
VTGIILTRVDGDARGGAALSMKMITDCPIKFIACGEKLSDLDDFYPDRIAKRILSMGDVVSLVEKAAEIVGQEEIDKLQK
KVKKGKFDLNDLVGMLKTLSKMDGISNIMKFIPSSFTKKLSSSVPDDNKVKKYIAIINSMTEKERQNPDILNGKRRLRIS
KGSGTSVTDVNLLIKQYNQMSSMVNKFSKIDHSKLKESDLMDMLSRK

Sequences:

>Translated_447_residues
MFKSLTESLNSVFSKLRGKSIISEDDFNLAMREIRIALIEADVSLEVAKKFINDIKDKVIGEKVIKSVSPSQMIIKIVQD
NLVAVLGSEKSDLNLAAKPPAVIMMVGLQGAGKTTTSGKLALKLKKQKKKVMLASLDIYRPAAQKQLEVLGKQIDVQTLP
VVIDEKPVTITKRALAAAKNENYDVLILDTAGRLHIDNNMMNELKAVKEIASPAEVILVADAMIGQDSVNIAKSFNEIIG
VTGIILTRVDGDARGGAALSMKMITDCPIKFIACGEKLSDLDDFYPDRIAKRILSMGDVVSLVEKAAEIVGQEEIDKLQK
KVKKGKFDLNDLVGMLKTLSKMDGISNIMKFIPSSFTKKLSSSVPDDNKVKKYIAIINSMTEKERQNPDILNGKRRLRIS
KGSGTSVTDVNLLIKQYNQMSSMVNKFSKIDHSKLKESDLMDMLSRK
>Mature_447_residues
MFKSLTESLNSVFSKLRGKSIISEDDFNLAMREIRIALIEADVSLEVAKKFINDIKDKVIGEKVIKSVSPSQMIIKIVQD
NLVAVLGSEKSDLNLAAKPPAVIMMVGLQGAGKTTTSGKLALKLKKQKKKVMLASLDIYRPAAQKQLEVLGKQIDVQTLP
VVIDEKPVTITKRALAAAKNENYDVLILDTAGRLHIDNNMMNELKAVKEIASPAEVILVADAMIGQDSVNIAKSFNEIIG
VTGIILTRVDGDARGGAALSMKMITDCPIKFIACGEKLSDLDDFYPDRIAKRILSMGDVVSLVEKAAEIVGQEEIDKLQK
KVKKGKFDLNDLVGMLKTLSKMDGISNIMKFIPSSFTKKLSSSVPDDNKVKKYIAIINSMTEKERQNPDILNGKRRLRIS
KGSGTSVTDVNLLIKQYNQMSSMVNKFSKIDHSKLKESDLMDMLSRK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=438, Percent_Identity=31.0502283105023, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI226371618, Length=336, Percent_Identity=33.0357142857143, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI23308697, Length=309, Percent_Identity=27.1844660194175, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI295424842, Length=309, Percent_Identity=27.1844660194175, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI89061728, Length=143, Percent_Identity=35.6643356643357, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1788963, Length=425, Percent_Identity=49.1764705882353, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1789874, Length=299, Percent_Identity=35.7859531772575, Blast_Score=164, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17539958, Length=433, Percent_Identity=28.175519630485, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI193206261, Length=316, Percent_Identity=29.746835443038, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=419, Percent_Identity=32.4582338902148, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320498, Length=312, Percent_Identity=26.6025641025641, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17647949, Length=434, Percent_Identity=28.8018433179723, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24641198, Length=302, Percent_Identity=25.8278145695364, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49186; Mature: 49186

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSLTESLNSVFSKLRGKSIISEDDFNLAMREIRIALIEADVSLEVAKKFINDIKDKVI
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEKVIKSVSPSQMIIKIVQDNLVAVLGSEKSDLNLAAKPPAVIMMVGLQGAGKTTTSGKL
HHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCCCEECCCCEEEEEEECCCCCCCCCCCEE
ALKLKKQKKKVMLASLDIYRPAAQKQLEVLGKQIDVQTLPVVIDEKPVTITKRALAAAKN
EEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEECEEECCCCCHHHHHHHHHHCC
ENYDVLILDTAGRLHIDNNMMNELKAVKEIASPAEVILVADAMIGQDSVNIAKSFNEIIG
CCCEEEEEECCCCEEECHHHHHHHHHHHHHCCCHHEEEEEHHHHCCCHHHHHHHHHHHHH
VTGIILTRVDGDARGGAALSMKMITDCPIKFIACGEKLSDLDDFYPDRIAKRILSMGDVV
HHHHEEEECCCCCCCCCEEEEEHHHCCCCCEEECCCHHHHHHHHCHHHHHHHHHHHHHHH
SLVEKAAEIVGQEEIDKLQKKVKKGKFDLNDLVGMLKTLSKMDGISNIMKFIPSSFTKKL
HHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SSSVPDDNKVKKYIAIINSMTEKERQNPDILNGKRRLRISKGSGTSVTDVNLLIKQYNQM
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
SSMVNKFSKIDHSKLKESDLMDMLSRK
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFKSLTESLNSVFSKLRGKSIISEDDFNLAMREIRIALIEADVSLEVAKKFINDIKDKVI
CCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GEKVIKSVSPSQMIIKIVQDNLVAVLGSEKSDLNLAAKPPAVIMMVGLQGAGKTTTSGKL
HHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCCCEECCCCEEEEEEECCCCCCCCCCCEE
ALKLKKQKKKVMLASLDIYRPAAQKQLEVLGKQIDVQTLPVVIDEKPVTITKRALAAAKN
EEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEECEEECCCCCHHHHHHHHHHCC
ENYDVLILDTAGRLHIDNNMMNELKAVKEIASPAEVILVADAMIGQDSVNIAKSFNEIIG
CCCEEEEEECCCCEEECHHHHHHHHHHHHHCCCHHEEEEEHHHHCCCHHHHHHHHHHHHH
VTGIILTRVDGDARGGAALSMKMITDCPIKFIACGEKLSDLDDFYPDRIAKRILSMGDVV
HHHHEEEECCCCCCCCCEEEEEHHHCCCCCEEECCCHHHHHHHHCHHHHHHHHHHHHHHH
SLVEKAAEIVGQEEIDKLQKKVKKGKFDLNDLVGMLKTLSKMDGISNIMKFIPSSFTKKL
HHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
SSSVPDDNKVKKYIAIINSMTEKERQNPDILNGKRRLRISKGSGTSVTDVNLLIKQYNQM
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHH
SSMVNKFSKIDHSKLKESDLMDMLSRK
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA