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The map label for this gene is sucD [H]

Identifier: 190571355

GI number: 190571355

Start: 1027601

End: 1028482

Strand: Reverse

Name: sucD [H]

Synonym: WPa_0960

Alternate gene names: 190571355

Gene position: 1028482-1027601 (Counterclockwise)

Preceding gene: 190571356

Following gene: 190571353

Centisome position: 69.38

GC content: 41.5

Gene sequence:

>882_bases
ATGTCCGTTTTAGTAAACAAAGATACAAGATTAATATGCCAGGGTTTTACTGGTGCACAAGGCACATTTCATTCAGAGCA
AGCAATTGATTACGGAACGAAAATGGTGGGAGGTGTAACTCCTGGAAAGGGTGGTAGCACTCACCTTAATTTACCGGTTT
TTAATACTGTAGCAGAAGCCAAAGAAAAAACCTGTGCAAATGCTACAGTTATATATGTACCTGCTAAATTTGCTGCTGCT
GCAATACTTGAAGCAATAGATGCAAAAATAGAATTGATAATTTGTATTACAGAGGGCATTCCTATACTTGACATGGTAAA
GGTAAAGCATGCTCTCGCTGGTTCAAACAGTCGATTGATTGGCCCAAACTGTCCAGGGGTTATTACACCTGAAGAATGCA
AAATAGGAATTATGCCAGGACATATTCACAAACGTGGACATATAGGAATTATGTCTCGCTCTGGAACTTTAACTTATGAA
GCGGTAGCACAAACAACTGCTGTTGGTCTTGGTCAATCCACGTGTATCGGAATTGGGGGGGATCCAGTTCATGGTATGAC
ATTTGTTGACTGTATGGAGCTCTTTTTAAAAGATGACGATACTCATGGTATTGTAGTTATTGGTGAAATAGGTGGAAACG
AAGAAGAAGATGTATCACATTTTGTGAAAACAGAAAAAACTAAAAAGCCAATCGTTGGTTTTGTAGCAGGCCAAACGGCA
CCTCCAGGAAGACGTATGGGACACGCTGGAGCAATCATCTCTTCCAGCGGTGGAAGTGCTGGTGCAAAGTTAGAGGTTAT
GCGCAGTGCTGGGATTGCGATTGCAGAAACCCCTGCTGTGATTGGTAAAAAGGTGTTAGAAGTAATGAGTGTCAGTGCCT
AG

Upstream 100 bases:

>100_bases
AGAAGGAAAAAAAATCTTAGAAGAGTCAGGATTAAATATTATTGCTGCAGATGAACTGGGTGATGCTGCGCAAAAGATAG
TAAAAGAGGTAAAATAAAGC

Downstream 100 bases:

>100_bases
CCTAGGTCATAAAAACCCTATATCCCCAGTCATCAGTATATTTTTTGACCACTCAATCAGTAAATGACCTCCTGGTAAAT
GTACTGAAGTTTGTTTAGTA

Product: succinyl-CoA synthetase, alpha subunit

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEAKEKTCANATVIYVPAKFAAA
AILEAIDAKIELIICITEGIPILDMVKVKHALAGSNSRLIGPNCPGVITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYE
AVAQTTAVGLGQSTCIGIGGDPVHGMTFVDCMELFLKDDDTHGIVVIGEIGGNEEEDVSHFVKTEKTKKPIVGFVAGQTA
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMSVSA

Sequences:

>Translated_293_residues
MSVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEAKEKTCANATVIYVPAKFAAA
AILEAIDAKIELIICITEGIPILDMVKVKHALAGSNSRLIGPNCPGVITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYE
AVAQTTAVGLGQSTCIGIGGDPVHGMTFVDCMELFLKDDDTHGIVVIGEIGGNEEEDVSHFVKTEKTKKPIVGFVAGQTA
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMSVSA
>Mature_292_residues
SVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEAKEKTCANATVIYVPAKFAAAA
ILEAIDAKIELIICITEGIPILDMVKVKHALAGSNSRLIGPNCPGVITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYEA
VAQTTAVGLGQSTCIGIGGDPVHGMTFVDCMELFLKDDDTHGIVVIGEIGGNEEEDVSHFVKTEKTKKPIVGFVAGQTAP
PGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMSVSA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=289, Percent_Identity=64.7058823529412, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI38569421, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI38569423, Length=260, Percent_Identity=29.2307692307692, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=63.3217993079585, Blast_Score=367, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17553126, Length=285, Percent_Identity=61.7543859649123, Blast_Score=346, Evalue=7e-96,
Organism=Caenorhabditis elegans, GI17550194, Length=285, Percent_Identity=58.9473684210526, Blast_Score=337, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17557344, Length=259, Percent_Identity=28.1853281853282, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17551266, Length=259, Percent_Identity=28.1853281853282, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324716, Length=294, Percent_Identity=48.2993197278912, Blast_Score=275, Evalue=4e-75,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=56.1643835616438, Blast_Score=336, Evalue=9e-93,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=61.3013698630137, Blast_Score=331, Evalue=3e-91,
Organism=Drosophila melanogaster, GI281363477, Length=257, Percent_Identity=28.0155642023346, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281363475, Length=257, Percent_Identity=28.0155642023346, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI281363473, Length=257, Percent_Identity=28.0155642023346, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30328; Mature: 30196

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEA
CCEEECCCCEEEEECCCCCCCCCCCHHHHHHCCHHHCCCCCCCCCCEEEECCHHHHHHHH
KEKTCANATVIYVPAKFAAAAILEAIDAKIELIICITEGIPILDMVKVKHALAGSNSRLI
HHHHCCCCEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYEAVAQTTAVGLGQSTCIGIGG
CCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVHGMTFVDCMELFLKDDDTHGIVVIGEIGGNEEEDVSHFVKTEKTKKPIVGFVAGQTA
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCC
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMSVSA
CCCCCCCCCCEEEECCCCCCCCEEEEEHHCCEEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLVNKDTRLICQGFTGAQGTFHSEQAIDYGTKMVGGVTPGKGGSTHLNLPVFNTVAEA
CEEECCCCEEEEECCCCCCCCCCCHHHHHHCCHHHCCCCCCCCCCEEEECCHHHHHHHH
KEKTCANATVIYVPAKFAAAAILEAIDAKIELIICITEGIPILDMVKVKHALAGSNSRLI
HHHHCCCCEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPEECKIGIMPGHIHKRGHIGIMSRSGTLTYEAVAQTTAVGLGQSTCIGIGG
CCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCCCEEEECCC
DPVHGMTFVDCMELFLKDDDTHGIVVIGEIGGNEEEDVSHFVKTEKTKKPIVGFVAGQTA
CCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCC
PPGRRMGHAGAIISSSGGSAGAKLEVMRSAGIAIAETPAVIGKKVLEVMSVSA
CCCCCCCCCCEEEECCCCCCCCEEEEEHHCCEEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]