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The map label for this gene is sucC

Identifier: 190571356

GI number: 190571356

Start: 1028486

End: 1029646

Strand: Reverse

Name: sucC

Synonym: WPa_0961

Alternate gene names: 190571356

Gene position: 1029646-1028486 (Counterclockwise)

Preceding gene: 190571357

Following gene: 190571355

Centisome position: 69.46

GC content: 35.23

Gene sequence:

>1161_bases
ATGAATATTCATGAATATCAAGCAAAGGAAATTTTACACAAGTTTAATGTCCCGGTACCAAAGGGTTTTGTTGCTACATC
TGCAGAAGGAGTAGAAACTCAAATAAATCAACTAAAATCTGACGTGTTTGTGGTTAAAGCTCAGATTCATGCAGGTGGTA
GGGGTAAGGCTGGTGGTGTAAAGCTAGCAAAGTCAGTTGAAGAAGCTCAACAGTTTGTAAAGAACATGCTCGGCATAACT
TTAGTTACTCATCAAACAGGGCCTAGTGGACAGCAGGTAAGAAGAATATACATTGAGGAAGGTTCAAGCATTAAAAAAGA
GTACTATTTGAGTCTAGTAGTTGATCCAAAGCTCAGTAGGTTAGTATTTATATTTTCCTCAGAAGGTGGTATGGATATTG
AAGAGGTAGCAAAAAATTCTCCTACAAAAATTGTGAAATTTGATATTGACCCTGCTACTGGTTTTACAAATCTTGATAAC
AGTAAACTTGCCAATAATTTTAATTTGAATTCAGAACAAATAGAAAGAATAACAAATATTGCAAAAAATATATATGATGC
GTTTATTACAACTGATGCAAGCCAAATAGAAATTAACCCACTAGTTGAAACAAATTCTGGGGATTTTGTTGCACTTGATG
CTAAAATTAATTTTGATGACAACGCTTTATATCGTCATCCAGAAATCGTGCAGCTTCGTGATTATGATGAAGAAGTTAAA
GAAGAGATAGAAGCTTCAAAACATGGACTTAGTTACATCAAAATGGATGGCAATATTGGTTGCATGGTGAACGGTGCAGG
TCTTGCTATGGCAACAATGGATATAATAAAGTACTATGGAGCAGAGCCTGCTAACTTTTTGGATGTTGGTGGTGGAGCGA
GTAAAGAAACTGTAACTGAAGCATTTAAAATCATATTGTCTGATAGCAACGTAAAAGGAATTCTGGTTAACATATTTGGT
GGTATAATGCGTTGCGATATTATCGCAAGTGGAATTGTTGCGGCTGCAAAAGAAATGAGCATTAAAGTTCCTCTAGTGGT
TAGATTATCAGGTACTAATTTTGAAGAAGGAAAAAAAATCTTAGAAGAGTCAGGATTAAATATTATTGCTGCAGATGAAC
TGGGTGATGCTGCGCAAAAGATAGTAAAAGAGGTAAAATAA

Upstream 100 bases:

>100_bases
TAAAAAAAAAGCTGAAGCAAGGAAAAAGAGGTATCAGCAAGAATGCAGAAGACAGCGTTATGGTTGGTAGTTTTTACTAA
GGTTAATAATTAGTTATCTT

Downstream 100 bases:

>100_bases
AGCATGTCCGTTTTAGTAAACAAAGATACAAGATTAATATGCCAGGGTTTTACTGGTGCACAAGGCACATTTCATTCAGA
GCAAGCAATTGATTACGGAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MNIHEYQAKEILHKFNVPVPKGFVATSAEGVETQINQLKSDVFVVKAQIHAGGRGKAGGVKLAKSVEEAQQFVKNMLGIT
LVTHQTGPSGQQVRRIYIEEGSSIKKEYYLSLVVDPKLSRLVFIFSSEGGMDIEEVAKNSPTKIVKFDIDPATGFTNLDN
SKLANNFNLNSEQIERITNIAKNIYDAFITTDASQIEINPLVETNSGDFVALDAKINFDDNALYRHPEIVQLRDYDEEVK
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFG
GIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEESGLNIIAADELGDAAQKIVKEVK

Sequences:

>Translated_386_residues
MNIHEYQAKEILHKFNVPVPKGFVATSAEGVETQINQLKSDVFVVKAQIHAGGRGKAGGVKLAKSVEEAQQFVKNMLGIT
LVTHQTGPSGQQVRRIYIEEGSSIKKEYYLSLVVDPKLSRLVFIFSSEGGMDIEEVAKNSPTKIVKFDIDPATGFTNLDN
SKLANNFNLNSEQIERITNIAKNIYDAFITTDASQIEINPLVETNSGDFVALDAKINFDDNALYRHPEIVQLRDYDEEVK
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFG
GIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEESGLNIIAADELGDAAQKIVKEVK
>Mature_386_residues
MNIHEYQAKEILHKFNVPVPKGFVATSAEGVETQINQLKSDVFVVKAQIHAGGRGKAGGVKLAKSVEEAQQFVKNMLGIT
LVTHQTGPSGQQVRRIYIEEGSSIKKEYYLSLVVDPKLSRLVFIFSSEGGMDIEEVAKNSPTKIVKFDIDPATGFTNLDN
SKLANNFNLNSEQIERITNIAKNIYDAFITTDASQIEINPLVETNSGDFVALDAKINFDDNALYRHPEIVQLRDYDEEVK
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTEAFKIILSDSNVKGILVNIFG
GIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKILEESGLNIIAADELGDAAQKIVKEVK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=46.1538461538462, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=44.4444444444444, Blast_Score=308, Evalue=5e-84,
Organism=Homo sapiens, GI294862256, Length=367, Percent_Identity=43.8692098092643, Blast_Score=289, Evalue=3e-78,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=50.7772020725389, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539378, Length=391, Percent_Identity=44.7570332480818, Blast_Score=327, Evalue=5e-90,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=42.9667519181586, Blast_Score=320, Evalue=8e-88,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=42.2391857506361, Blast_Score=330, Evalue=3e-91,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=45.3367875647668, Blast_Score=339, Evalue=1e-93,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=45.3367875647668, Blast_Score=339, Evalue=1e-93,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=44.9350649350649, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=44.9350649350649, Blast_Score=339, Evalue=2e-93,
Organism=Drosophila melanogaster, GI21356231, Length=390, Percent_Identity=43.5897435897436, Blast_Score=317, Evalue=1e-86,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_WOLPP (B3CME9)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975714.1
- EnsemblBacteria:   EBWOLT00000000364
- GeneID:   6384927
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0961
- GeneTree:   EBGT00050000031136
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42053; Mature: 42053

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKEILHKFNVPVPKGFVATSAEGVETQINQLKSDVFVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHCCCEEEEEEEEECCCCCCCCCH
KLAKSVEEAQQFVKNMLGITLVTHQTGPSGQQVRRIYIEEGSSIKKEYYLSLVVDPKLSR
HHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHEEEEEEECCCCCCEEEEEEEEECCCCCE
LVFIFSSEGGMDIEEVAKNSPTKIVKFDIDPATGFTNLDNSKLANNFNLNSEQIERITNI
EEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHH
AKNIYDAFITTDASQIEINPLVETNSGDFVALDAKINFDDNALYRHPEIVQLRDYDEEVK
HHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCEEEECCCCHHHH
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTE
HHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKGILVNIFGGIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKI
HHHHEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHHHH
LEESGLNIIAADELGDAAQKIVKEVK
HHHCCCEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKEILHKFNVPVPKGFVATSAEGVETQINQLKSDVFVVKAQIHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHCCCEEEEEEEEECCCCCCCCCH
KLAKSVEEAQQFVKNMLGITLVTHQTGPSGQQVRRIYIEEGSSIKKEYYLSLVVDPKLSR
HHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHEEEEEEECCCCCCEEEEEEEEECCCCCE
LVFIFSSEGGMDIEEVAKNSPTKIVKFDIDPATGFTNLDNSKLANNFNLNSEQIERITNI
EEEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHH
AKNIYDAFITTDASQIEINPLVETNSGDFVALDAKINFDDNALYRHPEIVQLRDYDEEVK
HHHHHHHHHCCCCCEEEEEEEEECCCCCEEEEEEEECCCCCCEECCCCEEEECCCCHHHH
EEIEASKHGLSYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASKETVTE
HHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKGILVNIFGGIMRCDIIASGIVAAAKEMSIKVPLVVRLSGTNFEEGKKI
HHHHEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHHHH
LEESGLNIIAADELGDAAQKIVKEVK
HHHCCCEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA