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The map label for this gene is folB [H]

Identifier: 190571099

GI number: 190571099

Start: 767199

End: 767576

Strand: Reverse

Name: folB [H]

Synonym: WPa_0696

Alternate gene names: 190571099

Gene position: 767576-767199 (Counterclockwise)

Preceding gene: 190571100

Following gene: 190571098

Centisome position: 51.78

GC content: 37.57

Gene sequence:

>378_bases
GTGGTAGCATGTAATCTTCTTATATCTGATTTACGGCTTTGGGTTCATTTGGGATGTAGTGCAGAAGAGAAGTTTTCTCC
CCAATTGGTGAGTATTGACGTTGATTTCACTTTTAAATCTCCTCCTTCAGGGCTTACAACTGATCAACTTAAAGATACTA
TCTGCTATTTGGAAGTAGTGCAAAATATTCAATCTCTTGTTCAGGGCAAGCAATTTAATTTAATCGAGCATTTAACTCAT
GATATATACAGGATGATTAACGACCTTTTTATGCAAAAAGAGCATTCTGTCAGGGTGACTACTCACAAAATCGCACCACC
AGTTCCTGGTGTGCATGGGGGCGTTTTTTTTACTTACTGTAATGAATTGCAAGAATGA

Upstream 100 bases:

>100_bases
ATGCAAGGCGCTGAAAAAGGAGCAAAACTCTTATGGGGTTTTCTTGATGGCATGATGAATGTTGATGTTTGTCATTAATT
ATAAGTAGATACTAAATTCA

Downstream 100 bases:

>100_bases
TCTATATTTCTATTGGATCAAATATAGGGAATCGCCTTTCCCATTTACAAAGAGCTACTGAGTTACTAAAGAAGCGCTAT
TTAAAAGACTTAAAGTCTTC

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MVACNLLISDLRLWVHLGCSAEEKFSPQLVSIDVDFTFKSPPSGLTTDQLKDTICYLEVVQNIQSLVQGKQFNLIEHLTH
DIYRMINDLFMQKEHSVRVTTHKIAPPVPGVHGGVFFTYCNELQE

Sequences:

>Translated_125_residues
MVACNLLISDLRLWVHLGCSAEEKFSPQLVSIDVDFTFKSPPSGLTTDQLKDTICYLEVVQNIQSLVQGKQFNLIEHLTH
DIYRMINDLFMQKEHSVRVTTHKIAPPVPGVHGGVFFTYCNELQE
>Mature_125_residues
MVACNLLISDLRLWVHLGCSAEEKFSPQLVSIDVDFTFKSPPSGLTTDQLKDTICYLEVVQNIQSLVQGKQFNLIEHLTH
DIYRMINDLFMQKEHSVRVTTHKIAPPVPGVHGGVFFTYCNELQE

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14219; Mature: 14219

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVACNLLISDLRLWVHLGCSAEEKFSPQLVSIDVDFTFKSPPSGLTTDQLKDTICYLEVV
CEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
QNIQSLVQGKQFNLIEHLTHDIYRMINDLFMQKEHSVRVTTHKIAPPVPGVHGGVFFTYC
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHH
NELQE
HHHCC
>Mature Secondary Structure
MVACNLLISDLRLWVHLGCSAEEKFSPQLVSIDVDFTFKSPPSGLTTDQLKDTICYLEVV
CEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
QNIQSLVQGKQFNLIEHLTHDIYRMINDLFMQKEHSVRVTTHKIAPPVPGVHGGVFFTYC
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHH
NELQE
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]