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The map label for this gene is ctrA [H]

Identifier: 190570997

GI number: 190570997

Start: 630467

End: 631237

Strand: Direct

Name: ctrA [H]

Synonym: WPa_0585

Alternate gene names: 190570997

Gene position: 630467-631237 (Clockwise)

Preceding gene: 190570992

Following gene: 190570998

Centisome position: 42.53

GC content: 36.84

Gene sequence:

>771_bases
ATGCGTATATTATTAATTGAAGATGATCAAGTAAGTGCAAGGACTGTAGTTAATGCCTTAACTTCTGATGGACATTTTTG
CGACGTTGTTACTTCTGCACAAGATTATAACAATAATATGGTTTCCTCGGGTGGAGACTGTTACGATCTAGTTATTCTAG
ATATACACCTGCCTGGTGATATTGATGGATATGATATACTGTTAAGATTAAGAAGTGCAAAAATCAAAGTTCCTGTTTTA
ATACTTTCGTGTATCTCCGCTGCCAACCATAAAGCTAAAGGACTTGGGTATGGTGCCGACGATTACTTAACCAAGCCATT
TCACAAGAGCGAATTATTAGCTCGAATTAAGGCCATAGTCCGACGTACTAAAGGCCATCCCGAATCAGTGATAAAGATTG
GTAATATGAATATCAATTTTGATCACAGGATTGTTGAGGTAAAAGGCAAAACAGTTCACCTTACTAACAAAGAGTATTCC
ATGATAGAATTGCTGGCATTGCGTAAAGGAGCAGTGTTGACAAAAGAAATGTTTTTAAACCATCTTTACAATGGCTTGGA
CGAACCTTCAGACAACAAAATAGTTGATGTTTTTATGTGTAAATTACGTAAAAAACTTGAAAGTGCAAATGACGGAATAA
GCCACATAGAAACCGTTTGGGGTAGAGGATATGTTCTAAAAGAGTATGTTGACGATGAAGAATACTCTAGTGTTAATATA
AGCGAAAGCAGTAGTGACTATCAAGCAGAACAAGTCAAGGACAGCGCATGA

Upstream 100 bases:

>100_bases
ATAAGTGTAATTTCTATTATTCATTAATAAAAATTTGATTTGTTACTTTCCTTGGTTATATATATTACTAAAATTATAAA
TTATTTATGGGGTGTAAAAT

Downstream 100 bases:

>100_bases
AATGCTTTATTTACTTGTTGATTGAAGAAGCGAAAAGGTAGATTTAGTAAGATAAAAACTAATCCTAAAAGTGAGGTAAC
GTGGTCAGTCTTTTAGAACT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRILLIEDDQVSARTVVNALTSDGHFCDVVTSAQDYNNNMVSSGGDCYDLVILDIHLPGDIDGYDILLRLRSAKIKVPVL
ILSCISAANHKAKGLGYGADDYLTKPFHKSELLARIKAIVRRTKGHPESVIKIGNMNINFDHRIVEVKGKTVHLTNKEYS
MIELLALRKGAVLTKEMFLNHLYNGLDEPSDNKIVDVFMCKLRKKLESANDGISHIETVWGRGYVLKEYVDDEEYSSVNI
SESSSDYQAEQVKDSA

Sequences:

>Translated_256_residues
MRILLIEDDQVSARTVVNALTSDGHFCDVVTSAQDYNNNMVSSGGDCYDLVILDIHLPGDIDGYDILLRLRSAKIKVPVL
ILSCISAANHKAKGLGYGADDYLTKPFHKSELLARIKAIVRRTKGHPESVIKIGNMNINFDHRIVEVKGKTVHLTNKEYS
MIELLALRKGAVLTKEMFLNHLYNGLDEPSDNKIVDVFMCKLRKKLESANDGISHIETVWGRGYVLKEYVDDEEYSSVNI
SESSSDYQAEQVKDSA
>Mature_256_residues
MRILLIEDDQVSARTVVNALTSDGHFCDVVTSAQDYNNNMVSSGGDCYDLVILDIHLPGDIDGYDILLRLRSAKIKVPVL
ILSCISAANHKAKGLGYGADDYLTKPFHKSELLARIKAIVRRTKGHPESVIKIGNMNINFDHRIVEVKGKTVHLTNKEYS
MIELLALRKGAVLTKEMFLNHLYNGLDEPSDNKIVDVFMCKLRKKLESANDGISHIETVWGRGYVLKEYVDDEEYSSVNI
SESSSDYQAEQVKDSA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=38.9380530973451, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=38.1578947368421, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.2105263157895, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=35.2678571428571, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=31.7391304347826, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=30.6034482758621, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=32.5892857142857, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=29.9559471365639, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=30.9734513274336, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788394, Length=233, Percent_Identity=29.1845493562232, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=175, Percent_Identity=32, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=28.1385281385281, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=28.0172413793103, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI145693140, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28619; Mature: 28619

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDQVSARTVVNALTSDGHFCDVVTSAQDYNNNMVSSGGDCYDLVILDIHLPGD
CEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCEEEEEEEEEECCCC
IDGYDILLRLRSAKIKVPVLILSCISAANHKAKGLGYGADDYLTKPFHKSELLARIKAIV
CCHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHH
RRTKGHPESVIKIGNMNINFDHRIVEVKGKTVHLTNKEYSMIELLALRKGAVLTKEMFLN
HHCCCCCCCEEEECCEEECCCEEEEEEECCEEEEECCCHHHHHHHHHHCCCHHHHHHHHH
HLYNGLDEPSDNKIVDVFMCKLRKKLESANDGISHIETVWGRGYVLKEYVDDEEYSSVNI
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEHHHCCCCCCCEEEC
SESSSDYQAEQVKDSA
CCCCCCHHHHHHCCCC
>Mature Secondary Structure
MRILLIEDDQVSARTVVNALTSDGHFCDVVTSAQDYNNNMVSSGGDCYDLVILDIHLPGD
CEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCEEEEEEEEEECCCC
IDGYDILLRLRSAKIKVPVLILSCISAANHKAKGLGYGADDYLTKPFHKSELLARIKAIV
CCHHHHHEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHH
RRTKGHPESVIKIGNMNINFDHRIVEVKGKTVHLTNKEYSMIELLALRKGAVLTKEMFLN
HHCCCCCCCEEEECCEEECCCEEEEEEECCEEEEECCCHHHHHHHHHHCCCHHHHHHHHH
HLYNGLDEPSDNKIVDVFMCKLRKKLESANDGISHIETVWGRGYVLKEYVDDEEYSSVNI
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEHHHCCCCCCCEEEC
SESSSDYQAEQVKDSA
CCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA