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The map label for this gene is sdhB [H]

Identifier: 190570992

GI number: 190570992

Start: 625919

End: 626707

Strand: Direct

Name: sdhB [H]

Synonym: WPa_0580

Alternate gene names: 190570992

Gene position: 625919-626707 (Clockwise)

Preceding gene: 190570991

Following gene: 190570997

Centisome position: 42.22

GC content: 33.84

Gene sequence:

>789_bases
ATGGTTCAGTTTTCTTTACCAAAAAATTCTAAAGTTAATAAAAAGGGCAAGATTTATCCTACTCCTACTGGAGCAAAAAA
TATTAGAAGATTTCAAATTTATCGTTGGTCTGCTGATGATGATAAAAATCCAAGAATAGACACATTTTTTATCGATATGG
ATAATTGTGGCCCTATGGTACTTGATGTATTAATAAAAATAAAGGATGAAATAGATTCAACCTTAACTTTTAGACGCTCT
TGTAGAGAAGGAATATGCGGATCTTGTGCAATGAATATTGATGGTACCAACACTCTTGCATGCACTAAATCTATACATGA
TATAAAAGGTGAAGTAAAAATATATCCACTACCTCATATGTATATAGTAAAGGATCTAGTTCCAGATCTAAGCCAATTTT
ATGAGCAATACAAATCGATTAAACCTTGGTTACAAACAGATAAATCTGCCTTACAAAATAAAGAATACTTTCAATCTCCT
GAAGATAGAAAAAAATTGGATGGTCTGTCTGATTGTATACTATGTGCTTGCTGTTCGACTGGTTGCCCAAGCTATTGGTG
GAATGGTGATAAATTTTTAGGGCCAGCGATATTACTGCAAGCTTATAGATGGATTGCTGACAGTCGTGATAATAAGAAAG
AAGAAAGACTTGCTTCTTTAAACGACCCATTTAAGTTGTATCGTTGTCATACAATAATGAATTGTACAAAAACCTGCCCG
AAAGGGCTTAACCCAGCAAAAGCGATAGCGAAAGTAAAACAGCTTATGGTAGAGAGAGAAGGAATTTGA

Upstream 100 bases:

>100_bases
GATTTTAGCTTTGCTTGAATTTGAAAAGGAAAAGTATGGTAGATAATACCAAAATATGTTATTTACAAAAAAGGGGTTTT
AGCTGTAAAAGGTAAGCAAT

Downstream 100 bases:

>100_bases
GTGTTATTTCTGGCACTCTTCGTAAGAAAATAGTAGACCCTCTGAAGCATAGGGTATTGTTAATACTCTAAACGTTCTTC
CATTCATGAAATGTATTGTT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MVQFSLPKNSKVNKKGKIYPTPTGAKNIRRFQIYRWSADDDKNPRIDTFFIDMDNCGPMVLDVLIKIKDEIDSTLTFRRS
CREGICGSCAMNIDGTNTLACTKSIHDIKGEVKIYPLPHMYIVKDLVPDLSQFYEQYKSIKPWLQTDKSALQNKEYFQSP
EDRKKLDGLSDCILCACCSTGCPSYWWNGDKFLGPAILLQAYRWIADSRDNKKEERLASLNDPFKLYRCHTIMNCTKTCP
KGLNPAKAIAKVKQLMVEREGI

Sequences:

>Translated_262_residues
MVQFSLPKNSKVNKKGKIYPTPTGAKNIRRFQIYRWSADDDKNPRIDTFFIDMDNCGPMVLDVLIKIKDEIDSTLTFRRS
CREGICGSCAMNIDGTNTLACTKSIHDIKGEVKIYPLPHMYIVKDLVPDLSQFYEQYKSIKPWLQTDKSALQNKEYFQSP
EDRKKLDGLSDCILCACCSTGCPSYWWNGDKFLGPAILLQAYRWIADSRDNKKEERLASLNDPFKLYRCHTIMNCTKTCP
KGLNPAKAIAKVKQLMVEREGI
>Mature_262_residues
MVQFSLPKNSKVNKKGKIYPTPTGAKNIRRFQIYRWSADDDKNPRIDTFFIDMDNCGPMVLDVLIKIKDEIDSTLTFRRS
CREGICGSCAMNIDGTNTLACTKSIHDIKGEVKIYPLPHMYIVKDLVPDLSQFYEQYKSIKPWLQTDKSALQNKEYFQSP
EDRKKLDGLSDCILCACCSTGCPSYWWNGDKFLGPAILLQAYRWIADSRDNKKEERLASLNDPFKLYRCHTIMNCTKTCP
KGLNPAKAIAKVKQLMVEREGI

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=236, Percent_Identity=67.7966101694915, Blast_Score=346, Evalue=2e-95,
Organism=Escherichia coli, GI1786943, Length=235, Percent_Identity=49.3617021276596, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI1790596, Length=224, Percent_Identity=33.0357142857143, Blast_Score=140, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17533915, Length=256, Percent_Identity=57.8125, Blast_Score=307, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6322987, Length=229, Percent_Identity=63.3187772925764, Blast_Score=316, Evalue=3e-87,
Organism=Drosophila melanogaster, GI17137106, Length=259, Percent_Identity=59.4594594594595, Blast_Score=338, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24643156, Length=233, Percent_Identity=63.0901287553648, Blast_Score=322, Evalue=1e-88,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 30015; Mature: 30015

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQFSLPKNSKVNKKGKIYPTPTGAKNIRRFQIYRWSADDDKNPRIDTFFIDMDNCGPMV
CEEECCCCCCCCCCCCCEEECCCCHHCCEEEEEEEECCCCCCCCCEEEEEEECCCCCHHH
LDVLIKIKDEIDSTLTFRRSCREGICGSCAMNIDGTNTLACTKSIHDIKGEVKIYPLPHM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEECCHH
YIVKDLVPDLSQFYEQYKSIKPWLQTDKSALQNKEYFQSPEDRKKLDGLSDCILCACCST
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHCCCHHHHHHCCHHHHHHHHHHCC
GCPSYWWNGDKFLGPAILLQAYRWIADSRDNKKEERLASLNDPFKLYRCHTIMNCTKTCP
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
KGLNPAKAIAKVKQLMVEREGI
CCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVQFSLPKNSKVNKKGKIYPTPTGAKNIRRFQIYRWSADDDKNPRIDTFFIDMDNCGPMV
CEEECCCCCCCCCCCCCEEECCCCHHCCEEEEEEEECCCCCCCCCEEEEEEECCCCCHHH
LDVLIKIKDEIDSTLTFRRSCREGICGSCAMNIDGTNTLACTKSIHDIKGEVKIYPLPHM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEEECCHH
YIVKDLVPDLSQFYEQYKSIKPWLQTDKSALQNKEYFQSPEDRKKLDGLSDCILCACCST
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHCCCHHHHHHCCHHHHHHHHHHCC
GCPSYWWNGDKFLGPAILLQAYRWIADSRDNKKEERLASLNDPFKLYRCHTIMNCTKTCP
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
KGLNPAKAIAKVKQLMVEREGI
CCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA