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The map label for this gene is tpiA [H]

Identifier: 190570950

GI number: 190570950

Start: 572297

End: 572998

Strand: Direct

Name: tpiA [H]

Synonym: WPa_0532

Alternate gene names: 190570950

Gene position: 572297-572998 (Clockwise)

Preceding gene: 190570947

Following gene: 190570951

Centisome position: 38.6

GC content: 32.34

Gene sequence:

>702_bases
ATGTCTTTTTTAATAGTAGCAAATTGGAAAATGAATGGAACACGTTCTTCATTTGTTGACTTTATAGGCAAACTTAACAA
CAAGAGCAACGAAATTACCTCTAAATTAGTAATTTGCCCTCCTTTTACATCATTTCAAAGCAATATAGAGTTGAACAACA
ATATTAAAATAGGAGGACAGAATTGCCATCATAAAGAGTTCGGTTCTTACACAGGTGAAATTAGTGCAGGAATGTTGAAG
GAACTAGGATGTAGTTACGTAATACTTGGACATTCTGAAAGGGCTCATGAAACAGATAGTGAAATAAAACTGAAATCAGA
AACAGCAATAGAATCAGGATTACACCCAATCATCTGTGTAGGTGAAAACTCAGAAGATTATAAAAATAAAAAAACAAAAG
AAGTAATAGAATATCAATGCAAAAACCGTTTGCCAACACAAGGTAAATATACCATAGCATACGAACCGATATGGGCAATA
GGAACAGGAAATGTGCCAAATAATGACGCAATTGCTGAGGTAATAAAATCCTGTACTGGTAAAAAACACATTATATATGG
TGGTTCAGTCAGTTCAGAAAATATAGAAAACTTGCTCAGTATTCCAAATTTATCAGGAGTTTTAATTGGCAGTGCAAGCT
TAGATTTTGATCACTTTTATAAAATCATACAACAAGTCGAGAAAAAATTTTCTCTTAATTAA

Upstream 100 bases:

>100_bases
AATGCCGGCTTAGCTCAATTGGTAGAGCAACTGACTTGTAATCAGTAGGTTGTCAGTTCAAGTCCGACAGCCGGCACTCT
CATTCATATAAGAAAAATTG

Downstream 100 bases:

>100_bases
TTCTAAAGGATAAATACTCTTATTGTCATGGCAAGGGAGTTGGCAAAATGTGTCAAGGAGTTTTCTATTGGCTAAGGTTG
TGACAATAAAGTTAAGCACT

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSFLIVANWKMNGTRSSFVDFIGKLNNKSNEITSKLVICPPFTSFQSNIELNNNIKIGGQNCHHKEFGSYTGEISAGMLK
ELGCSYVILGHSERAHETDSEIKLKSETAIESGLHPIICVGENSEDYKNKKTKEVIEYQCKNRLPTQGKYTIAYEPIWAI
GTGNVPNNDAIAEVIKSCTGKKHIIYGGSVSSENIENLLSIPNLSGVLIGSASLDFDHFYKIIQQVEKKFSLN

Sequences:

>Translated_233_residues
MSFLIVANWKMNGTRSSFVDFIGKLNNKSNEITSKLVICPPFTSFQSNIELNNNIKIGGQNCHHKEFGSYTGEISAGMLK
ELGCSYVILGHSERAHETDSEIKLKSETAIESGLHPIICVGENSEDYKNKKTKEVIEYQCKNRLPTQGKYTIAYEPIWAI
GTGNVPNNDAIAEVIKSCTGKKHIIYGGSVSSENIENLLSIPNLSGVLIGSASLDFDHFYKIIQQVEKKFSLN
>Mature_232_residues
SFLIVANWKMNGTRSSFVDFIGKLNNKSNEITSKLVICPPFTSFQSNIELNNNIKIGGQNCHHKEFGSYTGEISAGMLKE
LGCSYVILGHSERAHETDSEIKLKSETAIESGLHPIICVGENSEDYKNKKTKEVIEYQCKNRLPTQGKYTIAYEPIWAIG
TGNVPNNDAIAEVIKSCTGKKHIIYGGSVSSENIENLLSIPNLSGVLIGSASLDFDHFYKIIQQVEKKFSLN

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI226529917, Length=241, Percent_Identity=36.0995850622407, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI4507645, Length=241, Percent_Identity=36.0995850622407, Blast_Score=143, Evalue=1e-34,
Organism=Escherichia coli, GI1790353, Length=246, Percent_Identity=34.9593495934959, Blast_Score=142, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17536593, Length=240, Percent_Identity=36.25, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320255, Length=233, Percent_Identity=35.1931330472103, Blast_Score=133, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28572008, Length=240, Percent_Identity=35.4166666666667, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28572006, Length=240, Percent_Identity=35.4166666666667, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28572004, Length=240, Percent_Identity=35.4166666666667, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 25797; Mature: 25665

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLIVANWKMNGTRSSFVDFIGKLNNKSNEITSKLVICPPFTSFQSNIELNNNIKIGGQ
CEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEECCCEEECCC
NCHHKEFGSYTGEISAGMLKELGCSYVILGHSERAHETDSEIKLKSETAIESGLHPIICV
CCCCHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECHHHHHHCCCCEEEEE
GENSEDYKNKKTKEVIEYQCKNRLPTQGKYTIAYEPIWAIGTGNVPNNDAIAEVIKSCTG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHCCC
KKHIIYGGSVSSENIENLLSIPNLSGVLIGSASLDFDHFYKIIQQVEKKFSLN
CEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFLIVANWKMNGTRSSFVDFIGKLNNKSNEITSKLVICPPFTSFQSNIELNNNIKIGGQ
EEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEECCCEEECCC
NCHHKEFGSYTGEISAGMLKELGCSYVILGHSERAHETDSEIKLKSETAIESGLHPIICV
CCCCHHHCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECHHHHHHCCCCEEEEE
GENSEDYKNKKTKEVIEYQCKNRLPTQGKYTIAYEPIWAIGTGNVPNNDAIAEVIKSCTG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHCCC
KKHIIYGGSVSSENIENLLSIPNLSGVLIGSASLDFDHFYKIIQQVEKKFSLN
CEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA