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The map label for this gene is rho [H]

Identifier: 190570947

GI number: 190570947

Start: 568045

End: 569451

Strand: Direct

Name: rho [H]

Synonym: WPa_0529

Alternate gene names: 190570947

Gene position: 568045-569451 (Clockwise)

Preceding gene: 190570946

Following gene: 190570950

Centisome position: 38.32

GC content: 36.53

Gene sequence:

>1407_bases
ATGACAACAATCAATGAAGATGTCTTAGCAAAAGGAGGGGTTGTAGGTCAACCTGAAAAAAGCGAACAAATTCATAATGC
TGACGCAGTAAAACAAATGACCAGTGAAGGTGCTGAAAAAAACAAGAAAACATTGGACCTGAGCGAATTGAAAGAGAAAA
CAGCAGAAGAATTGTTAGAGCTAGCTGAAGAAAGAAAAATTTCAACTAGTGGTAAAGGCAATGGCAGGATGCTAAAACAG
GAAATGATATTCAGTTTAATGAAGAAAATGAGTGAAGAAGGAGGCATAACCACAGGAAGTGGAGTAGTGGAAATATTGCC
TGATGGTTTTGGTTTCTTACGTTCATCAAGTGCAAATTATGCTCCAAGTACCGATGATGTTTATATTTCCAATGGCCAAA
TAAAGAAGTTTAATTTACGTACAGGAGATATGGCATGTGGAGAAATAAGGCCACCTGGTGATAAAGAAAGATATTTTACT
TTAACTAAGGTTCAAAGTATAAACTCTACTGAAATCAGTGAATTAAGAAAGTACGTCCATTTTGATAATTTGCTTCCGCT
TTATCCTGAAAAAAGCCTCATCCTTGAAAACAACAGTAGCGGAGATAATAAAAAAGATATAAACATGCGTGCTGTAGATA
TAGTTACACCTCTTGGAAAAGGACAAAGAGCATTGATAGTTGCTCCACCTCGTACAGGAAAAACGATATTGCTTCAGCAA
ATGGCTCACTCTATAGCTACAAATCATCCTGAAATAGAACTAATAGTATTACTTATAGATGAAAGACCCGAAGAGGTGAC
AGATATGATACGCTCTGTAAAGGGTGAAGTGGTAAGCTCTACATTTGATGAACCTGCCTACCGTCATGTCCAACTTGCTG
AAATAGTAATAGAAAAAGCTAAAAGAATGGTTGAACACAAAAAAGATGTAGTGATTTTGCTTGATTCTATAACTCGTCTT
GCACGTGCTTATAATGCAGTCATTCCTTCGTCTGGAAAGGTTCTAACCGGCGGTGTAGATTCAAATGCGCTGCAAAGACC
AAAACGCTTTTTTGGAGCAGCTCGTAATATTGAAAATGGTGGTTCTTTGACAATCATCGCTACAGCCCTTATAGAAACTG
GTTCAAAAATGGATGATGTTATTTTTGAAGAGTTTAAAGGCACAGGTAATGCTGAAATTATACTAGATAGAAAACTTGCT
GATAAACGTATATTCCCTGCTATTGATATTACAAAATCCGGAACAAGGAAGGAAGAGCTATTAGTTGATAAGGCCATACT
AAATAAAATATGGGTATTGCGTAGGATACTTAACCCTATGGGATCTGTTGAAGCAATGGAGTTTTTACGTGACAAATTAC
TTTTAACAAAGAGCAATGCTGACTTTTTTAACTCCATGAATCACTAA

Upstream 100 bases:

>100_bases
AATTAAGTCTAAATACGCACTGAAAACTAGCTCAGCCTAATTTATTGTTTTATATTCACATTTTAGGTTAGTAAGCATCA
ATTAAAATTTTTGGAGGATT

Downstream 100 bases:

>100_bases
AAGTAAGCCAATTCTGATGGAGCAAAAAAGCAAAGCTCTCTTATAGCTAAAATAATTTGGATTTATCAAAATATATTAAG
CTGGCAATCTACCTTAAGTT

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho 1 [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTTINEDVLAKGGVVGQPEKSEQIHNADAVKQMTSEGAEKNKKTLDLSELKEKTAEELLELAEERKISTSGKGNGRMLKQ
EMIFSLMKKMSEEGGITTGSGVVEILPDGFGFLRSSSANYAPSTDDVYISNGQIKKFNLRTGDMACGEIRPPGDKERYFT
LTKVQSINSTEISELRKYVHFDNLLPLYPEKSLILENNSSGDNKKDINMRAVDIVTPLGKGQRALIVAPPRTGKTILLQQ
MAHSIATNHPEIELIVLLIDERPEEVTDMIRSVKGEVVSSTFDEPAYRHVQLAEIVIEKAKRMVEHKKDVVILLDSITRL
ARAYNAVIPSSGKVLTGGVDSNALQRPKRFFGAARNIENGGSLTIIATALIETGSKMDDVIFEEFKGTGNAEIILDRKLA
DKRIFPAIDITKSGTRKEELLVDKAILNKIWVLRRILNPMGSVEAMEFLRDKLLLTKSNADFFNSMNH

Sequences:

>Translated_468_residues
MTTINEDVLAKGGVVGQPEKSEQIHNADAVKQMTSEGAEKNKKTLDLSELKEKTAEELLELAEERKISTSGKGNGRMLKQ
EMIFSLMKKMSEEGGITTGSGVVEILPDGFGFLRSSSANYAPSTDDVYISNGQIKKFNLRTGDMACGEIRPPGDKERYFT
LTKVQSINSTEISELRKYVHFDNLLPLYPEKSLILENNSSGDNKKDINMRAVDIVTPLGKGQRALIVAPPRTGKTILLQQ
MAHSIATNHPEIELIVLLIDERPEEVTDMIRSVKGEVVSSTFDEPAYRHVQLAEIVIEKAKRMVEHKKDVVILLDSITRL
ARAYNAVIPSSGKVLTGGVDSNALQRPKRFFGAARNIENGGSLTIIATALIETGSKMDDVIFEEFKGTGNAEIILDRKLA
DKRIFPAIDITKSGTRKEELLVDKAILNKIWVLRRILNPMGSVEAMEFLRDKLLLTKSNADFFNSMNH
>Mature_467_residues
TTINEDVLAKGGVVGQPEKSEQIHNADAVKQMTSEGAEKNKKTLDLSELKEKTAEELLELAEERKISTSGKGNGRMLKQE
MIFSLMKKMSEEGGITTGSGVVEILPDGFGFLRSSSANYAPSTDDVYISNGQIKKFNLRTGDMACGEIRPPGDKERYFTL
TKVQSINSTEISELRKYVHFDNLLPLYPEKSLILENNSSGDNKKDINMRAVDIVTPLGKGQRALIVAPPRTGKTILLQQM
AHSIATNHPEIELIVLLIDERPEEVTDMIRSVKGEVVSSTFDEPAYRHVQLAEIVIEKAKRMVEHKKDVVILLDSITRLA
RAYNAVIPSSGKVLTGGVDSNALQRPKRFFGAARNIENGGSLTIIATALIETGSKMDDVIFEEFKGTGNAEIILDRKLAD
KRIFPAIDITKSGTRKEELLVDKAILNKIWVLRRILNPMGSVEAMEFLRDKLLLTKSNADFFNSMNH

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=422, Percent_Identity=59.9526066350711, Blast_Score=521, Evalue=1e-149,
Organism=Escherichia coli, GI1788251, Length=242, Percent_Identity=26.8595041322314, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 51873; Mature: 51742

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTINEDVLAKGGVVGQPEKSEQIHNADAVKQMTSEGAEKNKKTLDLSELKEKTAEELLE
CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LAEERKISTSGKGNGRMLKQEMIFSLMKKMSEEGGITTGSGVVEILPDGFGFLRSSSANY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHCCCCCC
APSTDDVYISNGQIKKFNLRTGDMACGEIRPPGDKERYFTLTKVQSINSTEISELRKYVH
CCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHH
FDNLLPLYPEKSLILENNSSGDNKKDINMRAVDIVTPLGKGQRALIVAPPRTGKTILLQQ
HCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHH
MAHSIATNHPEIELIVLLIDERPEEVTDMIRSVKGEVVSSTFDEPAYRHVQLAEIVIEKA
HHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KRMVEHKKDVVILLDSITRLARAYNAVIPSSGKVLTGGVDSNALQRPKRFFGAARNIENG
HHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCC
GSLTIIATALIETGSKMDDVIFEEFKGTGNAEIILDRKLADKRIFPAIDITKSGTRKEEL
CCEEEEEEHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCCCCCCHHHH
LVDKAILNKIWVLRRILNPMGSVEAMEFLRDKLLLTKSNADFFNSMNH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCCHHHHCCCC
>Mature Secondary Structure 
TTINEDVLAKGGVVGQPEKSEQIHNADAVKQMTSEGAEKNKKTLDLSELKEKTAEELLE
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LAEERKISTSGKGNGRMLKQEMIFSLMKKMSEEGGITTGSGVVEILPDGFGFLRSSSANY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHCCCCCC
APSTDDVYISNGQIKKFNLRTGDMACGEIRPPGDKERYFTLTKVQSINSTEISELRKYVH
CCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEHHCCCCCHHHHHHHHHHH
FDNLLPLYPEKSLILENNSSGDNKKDINMRAVDIVTPLGKGQRALIVAPPRTGKTILLQQ
HCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHH
MAHSIATNHPEIELIVLLIDERPEEVTDMIRSVKGEVVSSTFDEPAYRHVQLAEIVIEKA
HHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
KRMVEHKKDVVILLDSITRLARAYNAVIPSSGKVLTGGVDSNALQRPKRFFGAARNIENG
HHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCC
GSLTIIATALIETGSKMDDVIFEEFKGTGNAEIILDRKLADKRIFPAIDITKSGTRKEEL
CCEEEEEEHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCCCCCCHHHH
LVDKAILNKIWVLRRILNPMGSVEAMEFLRDKLLLTKSNADFFNSMNH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA