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The map label for this gene is wecB [H]

Identifier: 189499190

GI number: 189499190

Start: 201499

End: 202605

Strand: Direct

Name: wecB [H]

Synonym: Cphamn1_0206

Alternate gene names: 189499190

Gene position: 201499-202605 (Clockwise)

Preceding gene: 189499188

Following gene: 189499191

Centisome position: 7.36

GC content: 52.39

Gene sequence:

>1107_bases
GTGAAAAAGATTCTTTTAGCCGCCGGAGATCGTCAAGGTTTATTGAAGGTGCTGCCTCTATACAACGCGCTGCAGGAATA
TAATGGTTTTGAGCCGGTGCTGGCCGCCGGTGTGCCGCTGCCGGAAGGTGAACAGTCAGGTGAAAACCTTGCTGATCTGT
TCGGGATTGCAGACAAGGTTATCCCGGTCGAAACTTCAGGCGATACGCCCGTCGGACGAACCGCATCGGCAATGAAAGCT
TTTGAATCCCTTCTGCTTGCAGAACAACCTGATCTTGCCGTTGTCGGAGGAGATGACGATGTTGCTCTTGCCGCCGCTCT
CGCGGCAGCAAAGCTCAGTCTTCCTGTTGCAACTGTCGGGGCCGGAATGCGGGACTACAATCGACGTTCGCCCGCGGAAA
TCAACAGAAAGCTTATCGATTCGGTTTCCGATATACTCTTTGTCAGTGAGCACAGCGGTGAATATAACCTCATCAATGAA
GGGTTCGACGAGGAGAGGGTCTTTTTTGTCGGTGAGGTGGCTATCGACAGTCTTGCCGCTGTCATCAGCAGGGCAAACGA
TTCAGCGGTTGTAGACGATAGTGGAGTAGAAACCAAAAAGTATGTGCTGGTTCTTCTCGACCGTGCGGCTGCACTGGACG
ATCTGGAAATCCTGAAGAAAATTGAGCGTCTGGTAATCGTTCTGGCCGGGAAACAGCAGGTATTGATGCTGCTCGATCCC
GAAGTTGCAGCGGTTTTGAAGCAGCATGAGATGGAGCCTGCATTTACCATGGTTTCTGGTGTTCGGGTCAGGCCATCGAC
AGGCTATGTCGAGCTGCTGCGGCTTGTGAAGGATGCTTCCTTCATCCTGACCGATTCCAGCGCTGTCCAGACTGAGTCAA
CAGTCATGAAAGTACCCTGTCTTACCATGCTTGACGAAACGCCCAGTCCCGCTACCATCGAGATCGGCACCAACATTCTT
GTCGGAGACAGGGAAGAGGATATTCTTCAGAGCATCGACGAGGCTGCCAGGGGTGAAATTGGCAAACATGCCAGGATCCC
TGAAAAATGGGACGGCACCGCATCTCAACGGATTGTCGATGTGCTGGAGAAACTCCTGAGTGTGTAA

Upstream 100 bases:

>100_bases
CAGGAGCAGTATGCGCACAAGTATAGTGATTCCCTTCATCATGATCGTGTGTCTGTATAGGGATGGATGTGTTTGAAACT
AATGTAAAAAGATTTATCTC

Downstream 100 bases:

>100_bases
GGATGTGTAGGGACGGGCCCCTGTGCCTGCCCGTTTTCGTTCAATCAGAGGCTGAGGTCTCATGCGACTGAAAGAAATCG
TTCCCTGGGGTCGATCGTTC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKKILLAAGDRQGLLKVLPLYNALQEYNGFEPVLAAGVPLPEGEQSGENLADLFGIADKVIPVETSGDTPVGRTASAMKA
FESLLLAEQPDLAVVGGDDDVALAAALAAAKLSLPVATVGAGMRDYNRRSPAEINRKLIDSVSDILFVSEHSGEYNLINE
GFDEERVFFVGEVAIDSLAAVISRANDSAVVDDSGVETKKYVLVLLDRAAALDDLEILKKIERLVIVLAGKQQVLMLLDP
EVAAVLKQHEMEPAFTMVSGVRVRPSTGYVELLRLVKDASFILTDSSAVQTESTVMKVPCLTMLDETPSPATIEIGTNIL
VGDREEDILQSIDEAARGEIGKHARIPEKWDGTASQRIVDVLEKLLSV

Sequences:

>Translated_368_residues
MKKILLAAGDRQGLLKVLPLYNALQEYNGFEPVLAAGVPLPEGEQSGENLADLFGIADKVIPVETSGDTPVGRTASAMKA
FESLLLAEQPDLAVVGGDDDVALAAALAAAKLSLPVATVGAGMRDYNRRSPAEINRKLIDSVSDILFVSEHSGEYNLINE
GFDEERVFFVGEVAIDSLAAVISRANDSAVVDDSGVETKKYVLVLLDRAAALDDLEILKKIERLVIVLAGKQQVLMLLDP
EVAAVLKQHEMEPAFTMVSGVRVRPSTGYVELLRLVKDASFILTDSSAVQTESTVMKVPCLTMLDETPSPATIEIGTNIL
VGDREEDILQSIDEAARGEIGKHARIPEKWDGTASQRIVDVLEKLLSV
>Mature_368_residues
MKKILLAAGDRQGLLKVLPLYNALQEYNGFEPVLAAGVPLPEGEQSGENLADLFGIADKVIPVETSGDTPVGRTASAMKA
FESLLLAEQPDLAVVGGDDDVALAAALAAAKLSLPVATVGAGMRDYNRRSPAEINRKLIDSVSDILFVSEHSGEYNLINE
GFDEERVFFVGEVAIDSLAAVISRANDSAVVDDSGVETKKYVLVLLDRAAALDDLEILKKIERLVIVLAGKQQVLMLLDP
EVAAVLKQHEMEPAFTMVSGVRVRPSTGYVELLRLVKDASFILTDSSAVQTESTVMKVPCLTMLDETPSPATIEIGTNIL
VGDREEDILQSIDEAARGEIGKHARIPEKWDGTASQRIVDVLEKLLSV

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=383, Percent_Identity=25.3263707571802, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 39517; Mature: 39517

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLAAGDRQGLLKVLPLYNALQEYNGFEPVLAAGVPLPEGEQSGENLADLFGIADKV
CCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHE
IPVETSGDTPVGRTASAMKAFESLLLAEQPDLAVVGGDDDVALAAALAAAKLSLPVATVG
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHC
AGMRDYNRRSPAEINRKLIDSVSDILFVSEHSGEYNLINEGFDEERVFFVGEVAIDSLAA
CCHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
VISRANDSAVVDDSGVETKKYVLVLLDRAAALDDLEILKKIERLVIVLAGKQQVLMLLDP
HHHCCCCCEEECCCCCCHHHEEEEEEHHHHCCHHHHHHHHHHHHEEEEECCCEEEEEECH
EVAAVLKQHEMEPAFTMVSGVRVRPSTGYVELLRLVKDASFILTDSSAVQTESTVMKVPC
HHHHHHHHHCCCHHHHHHHCCEECCCCCHHHHHHHHHCCCEEEECCCHHCCCHHHEECCH
LTMLDETPSPATIEIGTNILVGDREEDILQSIDEAARGEIGKHARIPEKWDGTASQRIVD
HHHHCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
VLEKLLSV
HHHHHHCC
>Mature Secondary Structure
MKKILLAAGDRQGLLKVLPLYNALQEYNGFEPVLAAGVPLPEGEQSGENLADLFGIADKV
CCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHE
IPVETSGDTPVGRTASAMKAFESLLLAEQPDLAVVGGDDDVALAAALAAAKLSLPVATVG
EEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHC
AGMRDYNRRSPAEINRKLIDSVSDILFVSEHSGEYNLINEGFDEERVFFVGEVAIDSLAA
CCHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCEEEEEHHHHHHHHHH
VISRANDSAVVDDSGVETKKYVLVLLDRAAALDDLEILKKIERLVIVLAGKQQVLMLLDP
HHHCCCCCEEECCCCCCHHHEEEEEEHHHHCCHHHHHHHHHHHHEEEEECCCEEEEEECH
EVAAVLKQHEMEPAFTMVSGVRVRPSTGYVELLRLVKDASFILTDSSAVQTESTVMKVPC
HHHHHHHHHCCCHHHHHHHCCEECCCCCHHHHHHHHHCCCEEEECCCHHCCCHHHEECCH
LTMLDETPSPATIEIGTNILVGDREEDILQSIDEAARGEIGKHARIPEKWDGTASQRIVD
HHHHCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
VLEKLLSV
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]