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The map label for this gene is trkH [H]

Identifier: 189499081

GI number: 189499081

Start: 80701

End: 82158

Strand: Reverse

Name: trkH [H]

Synonym: Cphamn1_0087

Alternate gene names: 189499081

Gene position: 82158-80701 (Counterclockwise)

Preceding gene: 189499082

Following gene: 189499078

Centisome position: 3.0

GC content: 50.96

Gene sequence:

>1458_bases
ATGAATTTTCCAGCGATATCTCACGTTCTGGGCGCTCTTCTCATGTTTATCGGCAGCACCATGCTCCTGCCCCTTGCCTG
CGCCCTGATATACAATGACGGTGATGCTCTCTCTCTGTTGATATCAATGGGGGTAACGGTCTCCATAGGATTTCCCTTCT
GGTGGAGTTTTCGAAAATACCGTGACCTGACGCTGAAAGACGGCCTTTTCATTGTCACGTTCGGCTGGATCCTCGTCTCA
TCTGTTTCAGCGTTGCCGTTCATGCTACACGGTACCATACCATCGTTTACCGACGCTTTTTTTGAAATGATGTCCGGCTA
CACAACCACCGGTGCAACCATTCTCGACGACATCGAATCAGTCCCTCACGGCCTGCTTTTCTGGCGAAGCACGACCCACC
TCATCGGAGGCATGGGCTTTATCATGGTCACCATCATCATTCTCCCCCTCCTCGGTATAGGAGGGATGCAGCTCTACAAG
GCGGAAGCCGATCCCGGTCAGGTCATAACCGGCGAAAAGTTTCTCCCTCGCGTCAAGCAGACCGCCGTGTGGCTCTGGGG
AATCTACCTTGCCCTGATTCTCATCCAGTCACTCCTGCTCTGGATAGGAGGCATGCCTGTTTTCGACTCTCTCTGTCACG
CTTTCGGCACGGTTTCCACTTCCGGTTACTCGACAAAGAACAGCAGTATCGGCTATTACGACAGCGCATGGATCGACTGG
ATAACCATCATTTTCATGTTTCTCGGGGGCATGGCCTTCATGATGCATTACCATATCCTGAAAAAGGACTGGGAACCCGT
CCGTAACAACACGGAAATACGCTGGTACATCGGTTTTGTCGTGTTTATCAGCTTGCTTGCCACACTGATTCTCTGGGCTA
CCGGAAGCTATAGCGGATTCTTCGATTCCATACGCCATGCAACCTTCCAGGTTGTTTCAATCCTGACAACAACCGGATTT
ACCACCGCAGACTATGAGCTTTGGCCTCAGTCTGCACAGATGCTTCTCATGATCGCCTGCTTCATCGGTGCGTGTGCGGG
CTCGACCACCAGCGGCATCAAGGTGGTGCACTACGAAATCATCTGCAAATACCTCTACGCCAACGGCAGGAAGTTCCTGC
AGCCTTTAGCCGTAGTGCCGATAAAGATCAACCAGAAAAATGTAGCCTCTTCCGTCGTAACACTTGCAGTCAGTTACTTT
ATTCTCAACATCTTTATGATCTTTGTGGGCAGTGCGATCATGACCCTGATCGACGACATGGATTTCTTCAGCTCCATGAG
TGCGGTTATCTCTGCGCTTTTCAACATAGGGCCCGCCTTTGGAGAAGTTGGCCCGACGCACACCTTTTCCCATGTCTCAA
CCGCAGGCAAATGGTTTCTTTCCTTCAATATGCTTACCGGACGCCTTGAGATGTTCACCGTCATGGTGATGTTCTACCCG
TCCTTCTGGAAAAAGTAA

Upstream 100 bases:

>100_bases
ACCGAACGACCTTGCTGTCGTGGTTTCAGCGACCAAGAGCCTCAAGGACGCACGCGAGCTTTTCAATTAATACCATCACA
ATGAAACCCGTCTTCGCTCA

Downstream 100 bases:

>100_bases
TTCAGCACAAGTCAAAGGTCAAAAGGGAAAAGGCAAAAACAAGAAAGAGCTGTTATAGGCAGAATCGCTTTATTTCGAGT
GTTTCAAGGCTTCCTTGTCT

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNFPAISHVLGALLMFIGSTMLLPLACALIYNDGDALSLLISMGVTVSIGFPFWWSFRKYRDLTLKDGLFIVTFGWILVS
SVSALPFMLHGTIPSFTDAFFEMMSGYTTTGATILDDIESVPHGLLFWRSTTHLIGGMGFIMVTIIILPLLGIGGMQLYK
AEADPGQVITGEKFLPRVKQTAVWLWGIYLALILIQSLLLWIGGMPVFDSLCHAFGTVSTSGYSTKNSSIGYYDSAWIDW
ITIIFMFLGGMAFMMHYHILKKDWEPVRNNTEIRWYIGFVVFISLLATLILWATGSYSGFFDSIRHATFQVVSILTTTGF
TTADYELWPQSAQMLLMIACFIGACAGSTTSGIKVVHYEIICKYLYANGRKFLQPLAVVPIKINQKNVASSVVTLAVSYF
ILNIFMIFVGSAIMTLIDDMDFFSSMSAVISALFNIGPAFGEVGPTHTFSHVSTAGKWFLSFNMLTGRLEMFTVMVMFYP
SFWKK

Sequences:

>Translated_485_residues
MNFPAISHVLGALLMFIGSTMLLPLACALIYNDGDALSLLISMGVTVSIGFPFWWSFRKYRDLTLKDGLFIVTFGWILVS
SVSALPFMLHGTIPSFTDAFFEMMSGYTTTGATILDDIESVPHGLLFWRSTTHLIGGMGFIMVTIIILPLLGIGGMQLYK
AEADPGQVITGEKFLPRVKQTAVWLWGIYLALILIQSLLLWIGGMPVFDSLCHAFGTVSTSGYSTKNSSIGYYDSAWIDW
ITIIFMFLGGMAFMMHYHILKKDWEPVRNNTEIRWYIGFVVFISLLATLILWATGSYSGFFDSIRHATFQVVSILTTTGF
TTADYELWPQSAQMLLMIACFIGACAGSTTSGIKVVHYEIICKYLYANGRKFLQPLAVVPIKINQKNVASSVVTLAVSYF
ILNIFMIFVGSAIMTLIDDMDFFSSMSAVISALFNIGPAFGEVGPTHTFSHVSTAGKWFLSFNMLTGRLEMFTVMVMFYP
SFWKK
>Mature_485_residues
MNFPAISHVLGALLMFIGSTMLLPLACALIYNDGDALSLLISMGVTVSIGFPFWWSFRKYRDLTLKDGLFIVTFGWILVS
SVSALPFMLHGTIPSFTDAFFEMMSGYTTTGATILDDIESVPHGLLFWRSTTHLIGGMGFIMVTIIILPLLGIGGMQLYK
AEADPGQVITGEKFLPRVKQTAVWLWGIYLALILIQSLLLWIGGMPVFDSLCHAFGTVSTSGYSTKNSSIGYYDSAWIDW
ITIIFMFLGGMAFMMHYHILKKDWEPVRNNTEIRWYIGFVVFISLLATLILWATGSYSGFFDSIRHATFQVVSILTTTGF
TTADYELWPQSAQMLLMIACFIGACAGSTTSGIKVVHYEIICKYLYANGRKFLQPLAVVPIKINQKNVASSVVTLAVSYF
ILNIFMIFVGSAIMTLIDDMDFFSSMSAVISALFNIGPAFGEVGPTHTFSHVSTAGKWFLSFNMLTGRLEMFTVMVMFYP
SFWKK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=489, Percent_Identity=38.4458077709611, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1787626, Length=486, Percent_Identity=31.4814814814815, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53953; Mature: 53953

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFPAISHVLGALLMFIGSTMLLPLACALIYNDGDALSLLISMGVTVSIGFPFWWSFRKY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCHHHHHHHH
RDLTLKDGLFIVTFGWILVSSVSALPFMLHGTIPSFTDAFFEMMSGYTTTGATILDDIES
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
VPHGLLFWRSTTHLIGGMGFIMVTIIILPLLGIGGMQLYKAEADPGQVITGEKFLPRVKQ
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCHHHHHHHHH
TAVWLWGIYLALILIQSLLLWIGGMPVFDSLCHAFGTVSTSGYSTKNSSIGYYDSAWIDW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
ITIIFMFLGGMAFMMHYHILKKDWEPVRNNTEIRWYIGFVVFISLLATLILWATGSYSGF
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHH
FDSIRHATFQVVSILTTTGFTTADYELWPQSAQMLLMIACFIGACAGSTTSGIKVVHYEI
HHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
ICKYLYANGRKFLQPLAVVPIKINQKNVASSVVTLAVSYFILNIFMIFVGSAIMTLIDDM
HHHHHHHCCHHHHCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFFSSMSAVISALFNIGPAFGEVGPTHTFSHVSTAGKWFLSFNMLTGRLEMFTVMVMFYP
HHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHH
SFWKK
HHHCC
>Mature Secondary Structure
MNFPAISHVLGALLMFIGSTMLLPLACALIYNDGDALSLLISMGVTVSIGFPFWWSFRKY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCHHHHHHHH
RDLTLKDGLFIVTFGWILVSSVSALPFMLHGTIPSFTDAFFEMMSGYTTTGATILDDIES
CCCCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
VPHGLLFWRSTTHLIGGMGFIMVTIIILPLLGIGGMQLYKAEADPGQVITGEKFLPRVKQ
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEECCHHHHHHHHH
TAVWLWGIYLALILIQSLLLWIGGMPVFDSLCHAFGTVSTSGYSTKNSSIGYYDSAWIDW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
ITIIFMFLGGMAFMMHYHILKKDWEPVRNNTEIRWYIGFVVFISLLATLILWATGSYSGF
HHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCHHH
FDSIRHATFQVVSILTTTGFTTADYELWPQSAQMLLMIACFIGACAGSTTSGIKVVHYEI
HHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
ICKYLYANGRKFLQPLAVVPIKINQKNVASSVVTLAVSYFILNIFMIFVGSAIMTLIDDM
HHHHHHHCCHHHHCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFFSSMSAVISALFNIGPAFGEVGPTHTFSHVSTAGKWFLSFNMLTGRLEMFTVMVMFYP
HHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHH
SFWKK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]